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GaP Seminar Series

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Casey Holliday - Advisors, Hanjoong Jo and Bob Nerem

"Discovery of Shear- and Side-specific mRNAs and miRNAs in Human Aortic Valvular Endothelial Cells"

Endothelial cells’ (ECs) role in aortic valve (AV) disease remains relatively unknown; however, disease preferentially occurs in the fibrosa. We hypothesize that disturbed, oscillatory shear conditions (OS) present on the fibrosa stimulate ECs to modify mRNAs and miRNAs inducing disease. Our goal and the focus of this talk is the identification of mRNAs and miRNAs differentially regulated by OS and laminar shear (LS) in AVECs from the fibrosa (fHAVECs) and ventricularis (vHAVECs). 


Hassan Masoud
 - Advisor, Alexander Alexeev

"Controlled Release of Nanoparticles from Responsive Microgel Capsules"

Steady and burst-like release of encapsulated nanoparticles from responsive microgel capsules can be induced by capsule swelling and deswelling. Steady release is controlled by particle diffusion thought swollen gel network, whereas fast release is enabled by the flow of encapsulated solvent from shrinking microcapsules. The latter can be facilitated by micro-rods embedded inside micro-carriers that stretch the membrane and prevent pore sealing.


The Graduate and Post-Doc (GaP) Seminar Series is a weekly event of research presentations by two graduate students or post-docs conducting bio-related research.  The series is organized and sponsored by the Parker H. Petit Institute for Bioengineering and Bioscience (IBB) with additional support from the Wallace H. Coulter Department of Biomedical Engineering. It is held every Wednesday at 12:00pm in IBB 1128 and refreshments are provided. If your research group or department would like to present at future seminars, please contact Manu Platt, PhD at manu.platt@bme.gatech.edu.

Status

  • Workflow Status:Published
  • Created By:Colly Mitchell
  • Created:07/26/2011
  • Modified By:Fletcher Moore
  • Modified:10/07/2016