The AI4Science Center has announced the first recipients of its semiannual seed grant competition. Supported by the Schools of Chemistry and Biochemistry, Physics, and Psychology, the seed grant aims to support the development of research projects centered on innovation and collaboration. 

“The selection committee received more than a dozen proposals that push the boundaries of AI-enabled science and encourage collaboration across units. I look forward to seeing the great science, strong results, and successful future external funding enabled by these seed grants,” says Dimitrios Psaltis, professor in the School of Physics and director of the AI4Science Center. 

Launched earlier this semester, the center promotes cross-disciplinary research on AI tools that address scientific challenges. The following three proposals were selected by the center based on their scientific goals, extent of interdisciplinary collaboration, and potential for outside funding: 

Spring 2026 AI4Science Center Seed Grant Recipients  

Graph Foundation Models for Protein Conformational Dynamics | School of Chemistry and Biochemistry 

• PIs: Professor Peter Kasson, School of Chemistry and Biochemistry; Professor JC Gumbard, School of Physics; Assistant Professor Amirali Aghazadeh, School of Electrical and Computer Engineering
• Graduate student: Jeffy Jeffy
• Team statement: “The AI4Science Center’s seed funding will allow us to complete and test a prototype of our new deep learning architecture for protein dynamics. We're super excited about the project and happy that this gives us support to pursue our new idea.”

Combinations of Verified AI and Domain Knowledge for New Insights in Theoretical Physics | School of Physics

• PIs: Assistant Professor Aishik Ghosh, School of Physics; Professor Vijay Ganesh, School of Computer Science
• Graduate student: Piyush Jha
• Team statement: “This seed funding gives us an opportunity to connect two fields in a way that could transform our approach to certain problems in theoretical physics.”

Harnessing the Manifold Geometry of Neural Representations for Robust LLM Safety | School of Psychology 

• PIs: Assistant Professor Audrey Sederberg, School of Psychology; Assistant Professor Pan Li, School of Electrical and Computer Engineering
• Graduate student: Ruixuan Deng
• Team statement: “Our project injects insights from human neuroscience directly into AI safety algorithm design, allowing us to move beyond black-box approaches toward more interpretable and principled safety mechanisms. By closing the loop, these computational models will also provide new feedback and insights for neuroscience.”