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(10-0329) Prof. Kwaku Dayie, University of Maryland
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Prof. Kwaku Dayie, University of Maryland
Dynamics of RNA catalysts and ribo-regulators: Structure alone is
not an adequate descriptor of function
Special Seminar
The unexpected discovery that RNAs can function as enzymes or ribozymes suggested that RNA might serve as a catalyst in the removal of introns via splicing in eukaryotic genes. The group II intron ribozymes can splice via a two-step mechanism similar to the spliceosome but without the need for protein cofactors. We will discuss our current understanding of group II intron function based on X-ray structures and our own NMR dynamics studies.
For more information contact Prof. Nick Hud (404-385-1162).
Status
- Workflow status: Published
- Created by: Shirley Tomes
- Created: 02/10/2010
- Modified By: Fletcher Moore
- Modified: 10/07/2016
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