event
(11-0127) Prof. Indraneel Ghosh, University of Arizona
Primary tabs
Prof. Indraneel Ghosh, University of Arizona
When it Takes Three to Tango: Ternary Design Paradigms for Sensors and Inhibitors
The central motivation of our research program is to develop methodologies that have the potential for illuminating chemistry in a biological context. Towards his goal, I will describe new paradigms for designing supramolecular protein and peptide architectures that can serve as:
I)Turn-on split-protein sensors that are designed to respond to a variety of macromolecular targets. Our current targets include DNA, RNA, and proteins/enzymes.
II) Bivalent Inhibitors for selectively targeting protein surfaces, particularly protein kinases.
For more information contact Prof. Seth Marder (404-385-6048).
Status
- Workflow status: Published
- Created by: Shirley Tomes
- Created: 08/15/2010
- Modified By: Fletcher Moore
- Modified: 10/07/2016
Categories
Keywords