GaP Seminar Series

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Karl Pendergrass - Advisor, Mike Davis, PhD

"H2O2 Acutely Upregulates Glutathione Peroxidase and Catalase mRNA levels in Cardiac Progenitor Cells"

Hydrogen peroxide (H2O2) is increased in the heart after myocardial infarction and inhibits cardiac regeneration. Cardiac progenitor cells (CPC) may form new cardiomyocytes. We sought to determine how H2O2 would affect regulation of angiotensin receptors. Since the balance between positive and negative angiotensin signaling plays a role in regulating migration, higher H2O2 concentrations may prevent CPC replacement of damaged cells

Sarah Griffiths - Advisor, Bob Nerem, PhD

"Human Platelet Lysate as an Alternative to Fetal Bovine Serum for the Expansion of Therapeutic Mesenchymal Stem Cells"

Mesenchymal stem cells (MSCs) are a promising source for cellular therapies. One of the current approaches to scale up MSC production includes the use of human platelet lysate (hPL) as an alternative media supplementation to fetal bovine serum (FBS). The effects of hPL on MSC growth, senescence and chemokine receptor profiles in comparison to FBS culture were investigated to determine the suitability of hPL for MSC expansion.

The Graduate and Post-Doc (GaP) Seminar Series is a weekly event of research presentations by two graduate students or post-docs conducting bio-related research.  The series is organized and sponsored by the Parker H. Petit Institute for Bioengineering and Bioscience (IBB) with additional support from the Wallace H. Coulter Department of Biomedical Engineering. It is held every Wednesday at 12:00pm in IBB 1128 and refreshments are provided. If your research group or department would like to present at future seminars, please contact Manu Platt, PhD at manu.platt@bme.gatech.edu.


  • Workflow Status:Published
  • Created By:Colly Mitchell
  • Created:07/26/2011
  • Modified By:Fletcher Moore
  • Modified:10/07/2016