Functional Molecular Imaging in the Brain

Event Details
  • Date/Time:
    • Thursday February 24, 2011 - Friday February 25, 2011
      10:00 am - 10:59 am
  • Location: IBB 1128
  • Phone: (404) 894-6228
  • URL:
  • Email:
  • Fee(s):
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Faculty Host: Xiaoping Hu (404) 712-2730


Summary Sentence: Alan Jasanoff, PhD - Massachusetts Institute of Technology

Full Summary: Bioengineering Seminar SeriesAlan Jasanoff, PhD  - Massachusetts Institute of Technology  Functional Molecular Imaging in the Brain

Functional magnetic resonance imaging (fMRI) with contrast agents sensitive to neural activity could have great impact in neuroscience by combining noninvasive whole-brain coverage with molecular-level specificity for neuronal events. My laboratory is developing molecular fMRI approaches based on molecular sensors we have designed to detect intra- and extracellular signalling events in the nervous system.  Our sensors are built on a variety of chemical platforms, ranging from small molecules to nanoparticles.  Protein-based contrast agents are of particular interest to us because of the possibility of gene-based brain delivery strategies and the availability of powerful protein engineering techniques.  Here we describe molecular engineering of several MRI sensors for neural activity, as well as the first efforts in our laboratory to perform functional neuroimaging with molecular specificity in living brains.

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In Campus Calendar

Parker H. Petit Institute for Bioengineering and Bioscience (IBB)

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BioE Seminar
  • Created By: Colly Mitchell
  • Workflow Status: Published
  • Created On: Feb 11, 2011 - 6:00am
  • Last Updated: Oct 7, 2016 - 9:54pm