Spring 2020 NANOFANS Webinar Series - “Nanotechnology in Infectious Diseases (Diagnostics/Therapeutics)”: Session 3 - “Point-of-Care Diagnostics via DNA-Based Isothermal Amplification and Paper Test”

Primary tabs

May 13, 2020 | 11AM-12PM | Spring 2020 NANOFANS Webinar Series - “Nanotechnology in Infectious Diseases (Diagnostics/Therapeutics)”: Session 3 - “Point-of-Care Diagnostics via DNA-Based Isothermal Amplification and Paper Test”

Gabe Kwong, Professor of Biomedical Engineering; Georgia Institute of Technology

"Spring 2020 NanoFANS (Focusing on Advanced Nanobio- Systems) program will be offered in a weekly webinar format during the month of May. The focus of this event will be “Nanotechnology in Infectious Diseases (Diagnostics/Therapeutics).”

In the current global pandemic situation, infectious diseases are the leading cause of mortality worldwide, with viruses such as, ebola, SARS-Cov, SARS-Cov-2 in particular, making global impact on healthcare and socio-economic development. The rapid development of drug resistance to currently available therapies and associated side effects leads to serious public health concern; hence, devising novel treatment strategies is of paramount importance. The application of nanotechnology in infectious diseases is fast-revolutionizing the biomedical field and the healthcare sector and has a potential to diagnose, treat and prevent diseases."

Abstract: The current SARS-CoV-2 pandemic has highlighted the importance for rapid testing to track and contain the outbreak of infectious diseases. Current tests rely on RT-qPCR which requires a thermocycler and limits point-of-care (POC) use. POC tests that can amplify signals without specialized instrumentation could be deployed for rapid screening
and reach a broader segment of the population. Here we will highlight strategies for isothermal amplification to allow major classes of biomarkers – including nucleic acids, proteins, and cells – to be detected with minimal sample processing. Central to our strategy is taking advantage of enzymatic turnover, such as with proteases or Cas12a, to amplify detection signals. We aim to adapt these methods with paper-based assays to allow visualization of test results by eye. These strategies are generalization to a broad range of diseases to increase access to POC testing.

Bio: Dr. Kwong is an Associate Professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory. His lab pioneers transformative biotechnologies to address frontier clinical challenges in cancer, organ transplant rejection, and infectious diseases. His work has published in leading scientific journals and featured by the media including The Economist, NPR, BBC, and WGBH-2, Boston’s PBS station. Dr. Kwong earned his B.S. with Highest Honors from UC Berkeley, his Ph.D. from Caltech with Professor James R. Heath, and conducted postdoctoral studies at MIT with Professor Sangeeta N. Bhatia. In recognition of his work, Dr. Kwong has been honored with selective distinctions including the Burroughs Wellcome Fund Career Award and the NIH Director’s New Innovator Award. Dr. Kwong co-founded Glympse Bio in 2015, and holds 20+ issued or pending patents in biomedical technology.

Registration Link: https://tinyurl.com/nanofanswebinar

Event Address: Webinar link will be sent to all those registered prior to the event


  • Workflow Status:Published
  • Created By:kkarunakaran3
  • Created:04/24/2020
  • Modified By:kkarunakaran3
  • Modified:04/24/2020