Micro-Physiological Systems Seminar Series

Event Details
  • Date/Time:
    • Monday February 10, 2020 - Tuesday February 11, 2020
      1:00 pm - 1:59 pm
  • Location: Krone Engineered Biosystems Building, Room 1005 - Atlanta, GA
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Shuichi Takayama, faculty host


Summary Sentence: "3D Human Brain models in Microfluidics for the Study of Neurological Disorders" - Hansang Cho, Ph.D. - Sungkyunkwan University & UNC at Charlotte

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Hansang Cho, Ph.D.
Assistant Professor
Department of Mechanical Engineering
Sungkyunkwan University & University of North Carolina at Charlotte

“3D Human Brain models in Microfluidics for the Study of Neurological Disorders”

With hundreds of billions of neurons and thousands of trillions of synaptic connections between them, the human brain is the most complex system on earth. However, there are no well-developed human brain models to study the brain activities in either laboratory environments or in animal bodies. Here, I present micro-scaled 3D environments that reconstruct a 3D human brain in Alzheimer’s disease (AD) by recapitulating AD signature of elevated levels of amyloid-beta (A-beta), tau proteins, activation of microglia, immune cells resident in a central nervous system (CNS), and consequent neuronal damage. In particular, the model mirrored microglial neurotoxic activities such as axonal cleavage and neurotoxic release.

Lunch will be provided at the beginning of the seminar.

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Additional Information

In Campus Calendar

Parker H. Petit Institute for Bioengineering and Bioscience (IBB)

Invited Audience
Faculty/Staff, Postdoc, Graduate students
IBB, go-PetitInstitute
  • Created By: Floyd Wood
  • Workflow Status: Published
  • Created On: Jan 22, 2020 - 2:08pm
  • Last Updated: Jan 22, 2020 - 2:08pm