Title:

Some Challenges in the Design and Application of Simulator
Experiments to Biomechanics and Biomaterials Research

Abstract:

This talk will demonstrate how simulator experiments can be combined
with physical experiments to solve problems of Biomechanics and the tissue
engineering of Biomaterials. Biomechanics applies mechanical engineering
principles to understand the movements of living things. The use of statistical
methods to help devise treatments of anomalies in the movements of living
systems will be described. Three classes of problems will be introduced to
illustrate this interdisciplinary Biomechanics/Statistical approach. We will
consider (1) the design of prosthetic joints, (2) the identification of the root
causes of prosthetic joint failures, and (3) the development of replacement
meniscal tissue.

Bio:

Professor Santner has contributed to the design and analysis of Selection and Ranking experiments, to the analysis of Discrete Data and most recently to the design and analysis of experiments that use deterministic computer simulator as research platforms. He has been a visiting professor at Purdue, Duke University, the University of Washington, and the University of Munich. Santner is a Fellow of the American Statistical Association, the Institute of Mathematical Statistics, and the American Association for the Advancement of Science.  Today's talk will describe several interdisciplinary problems which are at the confluence of Biomechanical Engineering and the Statistical analysis of finite element model data.