GT Neuro Seminar Series

Event Details
  • Date/Time:
    • Monday April 2, 2018
      11:15 am - 12:15 pm
  • Location: Krone Engineered Biosystems Building, Room 1005 - Atlanta, GA
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Chris Rozell - faculty host


Summary Sentence: “Genetic Dissection of Spinal Circuits Processing Mechanical Itch” - Bo Duan, Ph.D. - University of Michigan

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“Genetic Dissection of Spinal Circuits Processing Mechanical Itch”

Bo Duan, Ph.D.
Assistant Professor
Department of Molecular, Cellular and Developmental Biology
University of Michigan 

We have all experienced an itch. It is a modality of somatic sensation defined as an unpleasant sensation associated with the desire to scratch. Itch can be evoked in the skin directly by physical stimuli, such as gentle touch, referred as mechanical itch, or by chemical mediators, such as histamine, referred as chemical itch.  Mechanical itch was first described in healthy human subjects by Edward Titchener in 1909 that itch points were found in the skin by punctate stimulation with a fine hair. Under pathological conditions, mechanical itch is one of the common symptoms of most patients with chronic itch. In last decades, the neural circuits that transmit chemical itch have been well studied. The neural circuits processing mechanical itch, however, remain still unknown. My lab uses a combination of intersectional genetic manipulations, electrophysiology and behavior analyses to identify the key components of the spinal circuitry for mechanical itch in mice.

This presentation can be seen via videoconference on the Emory Campus HSRB E260

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Additional Information

In Campus Calendar

Parker H. Petit Institute for Bioengineering and Bioscience (IBB)

Invited Audience
Faculty/Staff, Graduate students
go-PetitInstitute, go-neuro, gtneuro
  • Created By: Floyd Wood
  • Workflow Status: Published
  • Created On: Mar 19, 2018 - 12:34pm
  • Last Updated: Mar 19, 2018 - 12:34pm