Integrated Cancer Research Center Seminar Series

Event Details
  • Date/Time:
    • Tuesday February 6, 2018 - Wednesday February 7, 2018
      4:00 pm - 4:59 pm
  • Location: Petit Biotechnology Building, Room 1128 - Atlanta, GA
  • Phone:
  • URL:
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  • Fee(s):
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John McDonald - faculty host


Summary Sentence: "Next-generation Sequencing (NGS) for Research and Clinical Applications: What’s Behind the Curtain?" - Viany Mittal, Ph.D. - ThermoFisher

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"Next-generation Sequencing (NGS) for Research and Clinical Applications: What’s Behind the Curtain?"

Vinay Mittal, Ph.D.
Bioinformatic Scientist

Massively parallel NGS technologies are increasingly used to characterize the mutational landscape of cancer in research and clinical settings. Relative to single gene molecular assays, NGS can efficiently interrogate thousands of relevant variants simultaneously. Research applications use whole exome or genome approaches to enable discovery of novel variants. In contrast, clinical applications use targeted approaches to monitor known cancer genes relevant to diagnosis, prognosis, and therapy selection. NGS requires robust bioinformatics and software workflows to accurately detect, annotate, and report the thousands of potential variants in each analysis. I will discuss how we analyze cancer genomic data to define the genetic drivers of cancer and the technology challenges inherent in the development of sample to answer solutions for precision oncology.

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Additional Information

In Campus Calendar

Parker H. Petit Institute for Bioengineering and Bioscience (IBB)

Invited Audience
Faculty/Staff, Graduate students
go-PetitInstitute, go-icrc-events, ICRC Seminar, go-icrc
  • Created By: Floyd Wood
  • Workflow Status: Published
  • Created On: Jan 11, 2018 - 10:48am
  • Last Updated: Jan 11, 2018 - 10:48am