50 Years of Solitude: The Genetic Basis of Adaptation of C. elegans to its Laboratory Environment 

Event Details
  • Date/Time:
    • Thursday September 7, 2017
      10:55 am
  • Location: Georgia Tech, EBB 1005
  • Phone:
  • URL:
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  • Fee(s):
    N/A
  • Extras:
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Summaries

Summary Sentence: A Biological Sciences Seminar by Patrick McGrath, Ph.D.

Full Summary: No summary paragraph submitted.

Abstract
Most biological traits have a strong genetic, or heritable, component.  Understanding how genetic variation influences these phenotypes will be important for understanding common, heritable diseases like autism. However, the genetic architecture controlling most biological traits is incredibly complex – hundreds of interacting genes and variants combine in unknown ways to create phenotype. The McGrath lab is interested in using fundamental mechanistic studies in C. elegans to identify, predict, and understand how genetic variation impacts phenotypes related to fitness. We are studying two strains strains of C. elegans that have grown in the lab since 1951 to understand how genetic changes affect development, reproduction, and lifespan. I this talk, I will describe our research combining quantitative genetics, CRISPR/Cas9, genomics, and computational approaches to address these questions.

More on Patrick McGrath

Additional Information

In Campus Calendar
Yes
Groups

College of Sciences, School of Biological Sciences

Invited Audience
Faculty/Staff, Public, Graduate students, Undergraduate students
Categories
Seminar/Lecture/Colloquium
Keywords
Patrick McGrath, School of Biological Sciences Seminar
Status
  • Created By: Jasmine Martin
  • Workflow Status: Published
  • Created On: Aug 16, 2017 - 11:22am
  • Last Updated: Aug 16, 2017 - 11:22am