The CRISPR Craze: Origins and Applications of CRISPR-Cas Immune Systems

Event Details
  • Date/Time:
    • Thursday April 20, 2017 - Friday April 21, 2017
      11:00 am - 11:59 am
  • Location: Georgia Tech, MoSE G011
  • Phone: 404-894-3700
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Summary Sentence: Rodolphe Barrangou, North Carolina State University

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Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), together with associated sequences (cas) constitute the CRISPR-Cas system, which provides adaptive immunity against invasive elements in many bacteria and most archaea. In prokaryotes, CRISPR-Cas systems afford DNA-encoded, RNA mediated, nucleic acid targeting, using a diverse set of Cas nucleases that yield various cleavage outcomes. Recently, the CRISPR machinery has been repurposed to fuel the Cas9-enabled genome editing craze. Actually, the democratization of CRISPR-based technologies in the past three years hinges on the portability and functionalities of these molecular machines, and has revolutionized biology. I will look back on the historical milestones that have paved the way for the CRISPR era, and discuss the diverse applications that have impacted and continue to shape the field of Medicine, Ag, Food and Biotechnology. I will also discuss efforts underway to repurpose CRISPR-Cas systems as programmable antimicrobials. Lastly, I will consider the impacts this transformative field has had on science and society, and discuss business implications of this disruptive technology. 

Additional Information

In Campus Calendar

School of Biological Sciences, College of Sciences

Invited Audience
Faculty/Staff, Public, Undergraduate students, Graduate students
School of Biological Sciences Seminar, Rodolphe Barrangou, Joshua Weitz
  • Created By: Jasmine Martin
  • Workflow Status: Published
  • Created On: Mar 7, 2017 - 1:25pm
  • Last Updated: Apr 13, 2017 - 5:12pm