BioE PhD Proposal presentation- Joshua Hooks

Event Details
  • Date/Time:
    • Friday September 9, 2016 - Saturday September 10, 2016
      1:00 pm - 2:59 pm
  • Location: CHOA Seminar room EBB 1005
  • Phone:
  • URL:
  • Email:
  • Fee(s):
    N/A
  • Extras:
Contact

Laura Paige

404.385.6655

Summaries

Summary Sentence: "Role of Mechanical Microenvironment on the Regulation of Lymphatic Function and Health"

Full Summary: BioE PhD Proposal Presentation- "Role of Mechanical Microenvironment on the Regulation of Lymphatic Function and Health"- Joshua Hooks

Advisor: 

J. Brandon Dixon, Ph.D. (ME/Georgia Institute of Technology)

 

Committee:

Andrés J. García, PhD (Georgia Institute of Technology)

C. Ross Ethier, PhD (BME/(Georgia Institute of Technology)

Michael Davis, PhD (BME/Georgia Institute of Technology & Emory University)

Mariappan Muthuchamy (Medical Physiology/Texas A&M)

 

Role of Mechanical Microenvironment on the Regulation of Lymphatic Function and Health

 

Failure of lymph fluid transport plays an important role in pathologies, such as lymphedema and lymphacele after organ donation. The lymphatic system plays a critical role in maintaining fluid homeostasis in all of the soft tissue of the body. Its ability to transport interstitial fluid is partially dependent on the intrinsic pumping capacity of lymphatic smooth muscle cells. Recently, our lab has shown that lymphatic collecting vessels near an injury never return to pre-injury levels of pumping and lymph transport, but factors that impact collecting vessel phenotype are poorly understood. The central hypothesis of this work is that the components of the extracellular matrix (ECM) and mechanics of the lymphatic microenvironment play a central role in the contractile phenotype of lymphatic muscle cells (LMCs). 

Additional Information

In Campus Calendar
No
Groups

Bioengineering Graduate Program

Invited Audience
Undergraduate students, Faculty/Staff, Graduate students
Categories
Other/Miscellaneous
Keywords
No keywords were submitted.
Status
  • Created By: Laura Paige
  • Workflow Status: Published
  • Created On: Aug 26, 2016 - 3:59am
  • Last Updated: Apr 13, 2017 - 5:14pm