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Graduate and Postdoc (GaP) Seminar Series

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Shereka Banton - Advisor, Gilda Barabino, PhD

"Exosomal Release of K562-derived MicroRNA: Implications for Sickle Cell Anemia"

Cells have been shown to “communicate” via their exosomal microRNA secretions in vitro. Sickle reticulocyte microRNA expression and possibly function differ compared to RBCs. We are currently investigating whether exosomes secreted by the K562 erythroid progenitor cell line contain microRNAs, and aim to provide a first insight into a possible mechanism of reticulocyte egress from the bone marrow that may be relevant to sickle cell anemia.

Luke Timmins - Advisor, Don Giddens, PhD

"Development of Computational Modeling Techniques to Examine the Association Between Wall Shear Stress and Coronary Allograft Vasculopathy Lesion Formation in Cardiac Transplant Patients"

Coronary allograft vasculopathy (CAV) is the most significant cause of morbidity and mortality for cardiac transplant patients (HTx) after the first year of survival. Furthermore, CAV represents one of the most accelerated forms of occlusive coronary artery disease. We report on the development of patient-specific computational modeling techniques to examine the co-localization of near wall blood flow patterns and CAV lesion formation.




Status

  • Workflow Status:Published
  • Created By:Colly Mitchell
  • Created:05/31/2012
  • Modified By:Fletcher Moore
  • Modified:10/07/2016