(0425) Dr. Angelo Bongiorno, GIT

Event Details
  • Date/Time:
    • Tuesday April 25, 2006
      4:00 pm - 5:00 pm
  • Location: Boggs B6A
  • Phone:
  • URL:
  • Email:
  • Fee(s):
    N/A
  • Extras:
Contact
Shirley Tomes
Chemistry & Biochemistry
Contact Shirley Tomes
404-894-0591
Summaries

Summary Sentence: Dr. Angelo Bongiorno, Georgia Tech

Full Summary: Dr. Angelo Bongiorno, Georgia Tech, School of Physics

Dr. Angelo Bongiorno, Georgia Tech, School of Physics

Oxidative damage to DNA: role of sequence and strand direction

ABSTRACT

Spontaneous oxidation of guanine residues in DNA generates 8-oxoguanine, a lesion related to carcinogenesis and aging. In this lecture, I presenta quantum mechanics/molecular mechanics (QM/MM) investigation of the oxidative damage caused by the reaction of water with ionized DNA. The results of the atomistic simulations elucidate the puzzling experimental evidence of an oxidative damage rate depending on the DNA sequence and strand direction.

For more information contact Dr. Rig Hernandez (404-894-0594).

Additional Information

In Campus Calendar
No
Groups

School of Chemistry and Biochemistry

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Categories
Seminar/Lecture/Colloquium
Keywords
chemistry, organic chemistry
Status
  • Created By: Shirley Tomes
  • Workflow Status: Published
  • Created On: Apr 20, 2006 - 8:00pm
  • Last Updated: Oct 7, 2016 - 9:57pm