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(08-1016) Prof. Scott Silverman, U of Illinois
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Prof. Scott Silverman, University of Illinois, Urbana-Champaign
DNA as a Catalyst for Bioorganic Chemistry
The Silverman laboratory studies fundamental and applied aspects of the nucleic acids, DNA and RNA. This presentation focuses on the development and application of DNA as a catalyst (deoxyribozyme). Our initial studies of DNA catalysts have focused on issues of chemical selectivity, especially regioselectivity and site-selectivity during ligation of two RNA substrates. More recently, our efforts are expanding to study deoxyribozymes that catalyze reactions of non-oligonucleotide substrates, including substrates that are small-molecule compounds and peptides, with an eye towards applications in vitro and in vivo.
For more information contact Dr. Yomi Oyelere (404-894-4047).
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- Workflow Status:Published
- Created By:Shirley Tomes
- Created:01/17/2008
- Modified By:Fletcher Moore
- Modified:10/07/2016
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