Molecular simulations of protein binding and switching

Event Details
  • Date/Time:
    • Thursday May 5, 2011
      4:00 pm - 5:00 pm
  • Location: MoSE 3201A
  • Phone:
  • URL:
  • Email:
  • Fee(s):
    N/A
  • Extras:
Contact

Shirley Tomes

404-894-0591

Summaries

Summary Sentence: Lillian Chong, PhD - University of Pittsburgh

Full Summary: Physical Chemistry Seminar Series "Molecular simulations of protein binding and switching"Lillian Chong, PhD - University of Pittsburgh

Physical Chemistry Seminar Series

Lillian Chong, PhD - University of Pittsburgh
Abstract:

A major challenge in the field of biomolecular simulations is to access the long-timescale dynamics of biologically relevant protein motions such as the relative motions of protein domains and allosteric transitions. My group uses a variety of approaches for providing detailed views of such motions that might aid the design of molecular sensors or therapeutics. In this talk, I will present recent applications to the simulation of large-scale conformational changes in bi-functional, two-domain protein switches, molecular association kinetics, and how nature might correct for “mistakes” in binding geometry for a model protein-peptide complex.

Related Links

Additional Information

In Campus Calendar
No
Groups

Parker H. Petit Institute for Bioengineering and Bioscience (IBB)

Invited Audience
No audiences were selected.
Categories
Seminar/Lecture/Colloquium
Keywords
Molecular simulations of protein binding and switching
Status
  • Created By: Colly Mitchell
  • Workflow Status: Published
  • Created On: Apr 27, 2011 - 5:39am
  • Last Updated: Oct 7, 2016 - 9:54pm