Integrated Cancer Research Center Seminar Series

Event Details
  • Date/Time:
    • Thursday November 30, 2017
      1:00 pm - 2:00 pm
  • Location: Atlanta, Petit Biotechnology Building, Room 1128 - Atlanta, GA
  • Phone:
  • URL:
  • Email:
  • Fee(s):
    N/A
Contact

Yuhong Fan - faculty host

Summaries

Summary Sentence: “Roles of Neural Stem and Progenitor Cells in the Development of Benign and Malignant Brain Tumors” - Yuan Zhu, Ph.D. - Children's National Medical Center

Full Summary: No summary paragraph submitted.


“Roles of Neural Stem and Progenitor Cells in the Development of Benign and Malignant Brain Tumors”

Yuan Zhu, Ph.D.
Professor
Scientific Director, Gilbert Family Neurofibromatosis Institute
Children’s National Medical Center

This presentation will focus on using genetically engineered mouse (GEM) models to study the role of neural stem and progenitor cells in the development of benign Grade I glioma and Grade IV malignant glioma, also known as glioblastoma (GBM), the most common primary brain in children and adults, respectively. Our study identifies a critical therapeutic window for targeting glial precursor cells during development in the context of neurofibromatosis type 1 (NF1)-associated Grade I glioma. Furthermore, we also reveal a less proliferative precursor population for highly aggressive GBMs, but surprisingly, these two GBM populations are anatomically located in the different regions of the brain.

Related Links

Additional Information

In Campus Calendar
Yes
Groups

Parker H. Petit Institute for Bioengineering and Bioscience (IBB)

Invited Audience
Faculty/Staff, Graduate students
Categories
Seminar/Lecture/Colloquium
Keywords
go-PetitInstitute, ICRC Seminar, go-icrc-events, go-icrc
Status
  • Created By: Floyd Wood
  • Workflow Status: Published
  • Created On: Nov 21, 2017 - 1:00pm
  • Last Updated: Nov 26, 2017 - 2:05pm