'Y' a Protein Might Matter in Glaucoma

Petit Institute lab of Raquel Lieberman makes groundbreaking discovery

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Petit Institute lab of Raquel Lieberman makes groundbreaking discovery

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Petit Institute lab of Raquel Lieberman makes groundbreaking discovery

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  • Raquel Lieberman Raquel Lieberman
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The lab of Petit Institute researcher Raquel Lieberman has made an important new discovery in a protein associated with glaucoma: a Y-shape.

This extreme oddity is significant to science, and possibly someday to medicine, particularly in the treatment of certain types of blindness.

“A protein like this one has never been reported before. There are extremely few Y-shapes in proteins at all,” said Lieberman, who led a two-year study, running the protein through a gauntlet of lab tests. The research has been published in the journal, Structure.

Lieberman, a structural biologist and associate professor in the School of Chemistry and Biochemistry, is an expert on myocilin, a protein sometimes implicated in a form of hereditary glaucoma, which is just one category of glaucoma – the second most common cause of blindness globally. Genetic mutations in myocilin are a major cause of hereditary glaucoma, which can strike at a particularly young age, including in childhood.

Read the entire story of this groundbreaking research here.

 

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Parker H. Petit Institute for Bioengineering and Bioscience (IBB)

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  • Created By: Jerry Grillo
  • Workflow Status: Published
  • Created On: Oct 20, 2017 - 10:41am
  • Last Updated: Oct 20, 2017 - 10:41am