Bioengineering Seminar Series

Event Details
  • Date/Time:
    • Thursday October 5, 2017
      11:00 am - 12:00 pm
  • Location: Parker H. Petit Institute for Bioengineering and Bioscience, Room 1128
  • Phone: (404) 894-6228
  • URL: Petit Institute website
  • Email:
  • Fee(s):
    N/A
  • Extras:
Contact

Wilbur Lam, M.D., Ph.D. - faculty host

Summaries

Summary Sentence: "Rubber vs. Silly Putty: Extracellular Matrix Viscoelasticity and its Impact on Cells" - Ovijit Chaudhuri, Ph.D. - Stanford University

Full Summary: No summary paragraph submitted.

Media
  • Parker H. Petit Institute for Bioengineering & Bioscience Parker H. Petit Institute for Bioengineering & Bioscience
    (image/jpeg)

"Rubber vs. Silly Putty: Extracellular Matrix Viscoelasticity and its Impact on Cells"

Ovijit Chaudhuri, Ph.D.
Assistant Professor
Department of Mechanical Engineering
Stanford University


The extracellular matrix is a complex assembly of structural proteins that provides physical support and biochemical signaling to cells in tissues. Over the last two decades, studies have revealed the important role that extracellular matrix elasticity plays in regulating a variety of biological processes in cells, including stem cell differentiation and cancer progression. However, tissues and matrix are often viscoelastic, exhibiting stress relaxation over time in response to a deformation. This talk will focus on our recent efforts to elucidate the viscoelastic properties of extracellular matrices, and then engineer new biomaterials for 3D culture in which the stress relaxation properties can be modulated independent of initial elasticity and cell adhesion ligand density. Using these materials, we find that the rate of stress relaxation regulates stem cell differentiation, cartilage matrix deposition by chondrocytes, cell division, and breast cancer cell invasion.

The Bioengineering Seminar Series is co-hosted by the Parker H. Petit Institute for Bioengineering and Bioscience, and the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University.

Related Links

Additional Information

In Campus Calendar
Yes
Groups

BBUGS, Bioengineering Graduate Program, Parker H. Petit Institute for Bioengineering and Bioscience (IBB), Wallace H. Coulter Dept. of Biomedical Engineering

Invited Audience
Faculty/Staff, Public, Graduate students, Undergraduate students
Categories
Seminar/Lecture/Colloquium
Keywords
IBB, BioE Seminar
Status
  • Created By: Colly Mitchell
  • Workflow Status: Published
  • Created On: Aug 8, 2017 - 11:01am
  • Last Updated: Aug 8, 2017 - 11:16am