Immune System Key: New Study Questions Earlier Conclusions

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Immune System Key: New Study Questions Earlier Conclusions

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Immune System Key: New Study Questions Earlier Conclusions about the Kinetics of T Cell Receptors

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  • Researchers from Georgia Tech and Emory University Researchers from Georgia Tech and Emory University
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T cell receptors are among the most important molecules in the immune system because of their role in recognizing the antigens that signal such threats as viruses and cancer. The receptors must also distinguish these threats from the body’s own cells to avoid triggering an unwanted immune system response.

Recognition requires direct physical contact between the receptor and the antigen. Researchers attempting to understand this critical mechanism, therefore, have been studying such factors as the affinity for interaction between antigens and T cell receptors, how long those interactions last and how rapidly they occur. Information about these interactions has come mostly from studying receptor molecules removed from the outer membranes of T cells – the location where they normally operate.

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Zhu Lab

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Parker H. Petit Institute for Bioengineering and Bioscience (IBB)

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Institute and Campus, Cancer Research, Institute Leadership, Chemistry and Chemical Engineering, Student and Faculty, Engineering, Life Sciences and Biology, Research, Physics and Physical Sciences
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Keywords
Cheng Zhu, Georgia Tech, IBB, Immune System Key: New Study Questions Earlier Conclusions about the Kinetics of T Cell Receptors
Status
  • Created By: Colly Mitchell
  • Workflow Status: Published
  • Created On: Jun 20, 2010 - 8:00pm
  • Last Updated: Oct 7, 2016 - 11:06pm