The Right Recipe

Contact
Floyd Wood
IBB
Contact Floyd Wood
Sidebar Content
No sidebar content submitted.
Summaries

Summary Sentence:

A new microparticle-drug combination may be key to reducing infl

Full Summary:

Researchers believe that a number of anti-inflammatory drugs, if delivered directly into the heart following heart attack, could prevent permanent damage and prolong heart function. The challenge, however, is finding an effective way to deliver the drugs. Some drugs require such large doses that toxicity becomes a risk. Others must be injected daily. Certain drug delivery methods themselves can cause inflammation.

Media
  • Pulse Pulse
    (image/jpeg)

An Emory research team believes it has found the right recipe of ingredients to one day make safe, effective drug-laden microparticles for heart attack patients.

The team, led by biomedical engineer Michael E. Davis, found that injecting animal hearts with microparticles formulated with the polymer PCADK—poly(cyclohexane-1,4-diylacetone dimethylene ketone)—improved cardiac function after simulated heart attack. Unlike other “carrier” molecules, PCADK degrades into two benign substances: 1,4-cyclohexanedimethanol, an FDA-approved food additive, and acetone, an endogenous compound.

Read more

Additional Information

Groups

Parker H. Petit Institute for Bioengineering and Bioscience (IBB)

Categories
Institute and Campus, Student and Faculty, Engineering, Research
Related Core Research Areas
No core research areas were selected.
Newsroom Topics
No newsroom topics were selected.
Keywords
Biomedical Engineering, gtech, Heart Disease, IBB
Status
  • Created By: Floyd Wood
  • Workflow Status: Published
  • Created On: Jul 27, 2009 - 8:00pm
  • Last Updated: Oct 7, 2016 - 11:06pm