Biofluids Seminar

Event Details
  • Date/Time:
    • Tuesday March 1, 2016
      12:30 pm - 1:30 pm
  • Location: Molecular Science 1222
  • Phone:
  • URL:
  • Email:
  • Fee(s):
    N/A
  • Extras:
Contact

David Ku, M.D., Ph.D. - faculty host

Summaries

Summary Sentence: "A Novel Simulation Method for the Computation of Coronary Hemodynamics and its Clinical Validation" - Eun Bo Shim, Ph.D. - National Research Laboratory of Biosystems Engineering, Kangwon National University

Full Summary: No summary paragraph submitted.

"A Novel Simulation Method for the Computation of Coronary Hemodynamics and its Clinical Validation"

Eun Bo Shim, Ph.D.
Professor
National Research Laboratory of Biosystems Engineering
Kangwon National University


In this seminar I introduce a vessel-length based simulation method to compute coronary fractional flow reserve. This method used the miscrovascular resistance values calculated from coronary vessel lengths. To validate the scheme for the computation of fractional flow reserve (FFR) based on coronary computed tomographic angiography (CCTA) data, we compared them with invasively measured FFR, and evaluated its diagnostic performance with that of CCTA. One hundred seventeen patients from 4 medical insti! tutions who had clinically indicated invasive coronary angiography for suspected coronary artery disease (CAD) were enrolled. Invasive FFR measurement was performed in 218 vessels (87 of which had an FFR ≤0.80); these measurements were regarded as the reference standard. The diagnostic characteristics of CCTA-derived computational FFR (CT-FFR) and CCTA were evaluated against those of invasively measured FFR. With a novel method of vessel-length based CFD scheme, CT-FFR can be easily performed at a personal computer enhancing its applicability in clinical situation. The diagnostic accuracy of CT-FFR for the detection of functionally significant CAD was good and was superior to that of CCTA within a population with a high prevalence of CAD. 

 

Related Links

Additional Information

In Campus Calendar
Yes
Groups

Parker H. Petit Institute for Bioengineering and Bioscience (IBB)

Invited Audience
Undergraduate students, Faculty/Staff, Graduate students
Categories
Seminar/Lecture/Colloquium
Keywords
graduate students
Status
  • Created By: Colly Mitchell
  • Workflow Status: Published
  • Created On: Feb 24, 2016 - 5:41am
  • Last Updated: Apr 13, 2017 - 5:16pm