New Surveillance Process for Detection of Liver Cancer Could Improve Survival Rate

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Barbara Christopher
Industrial and Systems Engineering
404.385.3102

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Summaries

Summary Sentence:

In collaboration with MD Anderson Cancer Center, ISyE’s Turgay Ayer and team are proposing a novel modeling framework to determine the most cost-effective practical policies from a societal perspective to detect liver cancer.

Full Summary:

Hepatocellular carcinoma, the most common type of liver cancer, is the fastest growing cause of cancer-related death in the United States. In collaboration with MD Anderson Cancer Center, ISyE’s Turgay Ayer and team are proposing a novel modeling framework to determine the most cost-effective practical policies from a societal perspective to detect liver cancer.

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  • Turgay Ayer Turgay Ayer
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Hepatocellular carcinoma (HCC), the most common type of liver cancer, is the fastest growing cause of cancer-related death in the United States.  While early detection of HCC through regular surveillance can improve survival, the optimal surveillance policies are unknown as of now.

In collaboration with MD Anderson Cancer Center, ISyE’s Turgay Ayer and team are proposing a novel modeling framework to determine the most cost-effective practical policies from a societal perspective to detect liver cancer.

In contrast to existing policies, the model considers surveillance policies that are stratified by patients' liver condition and age. The research team carefully calibrated the model parameters based on the best evidence from previously published observational studies. The results demonstrate that their proposed policies are more cost-effective than the recommended one-size-fits-all policies. Furthermore, unlike current surveillance policies, expanding surveillance to non-cirrhotic patients has great potential to improve survival outcomes and cost-effectiveness. 

Additional Information

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H. Milton Stewart School of Industrial and Systems Engineering (ISYE)

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Student and Faculty
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Keywords
health, health & humanitarian systems, HHL, hhs, isye, liver cancer, Turgay Ayer
Status
  • Created By: Lizzie Millman
  • Workflow Status: Published
  • Created On: Sep 11, 2014 - 6:43am
  • Last Updated: Oct 7, 2016 - 11:17pm