Emergent Behaviors of Integrated Cellular Systems (EBICS) Distinguished Lecturer

Event Details
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Lakeita Servance

Summaries

Summary Sentence: "The Costs and Consequences of Biological Control" - Arthur Lander, MD, PhD, University of California, Irvine

Full Summary: Emergent Behaviors of Integrated Cellular Systems (EBICS) Distinguished Lecturer - "The Costs and Consequences of Biological Control" - Arthur Lander, MD, PhD, University of California, Irvine

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  • Arthur D. Lander, MD, PhD - University of California, Irvine Arthur D. Lander, MD, PhD - University of California, Irvine
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"The Costs and Consequences of Biological Control"

Arthur D. Lander, MD, PhD
Center for Complex Biological Systems
Departments of Developmental & Cell Biology and Biomedical Engineering
University of California, Irvine


After a century of great strides in identifying the components and mechanisms out of which living things are constructed, biologists are increasingly turning (or returning) to questions of biological organization:  Why are biological systems built the way they are?  What explains the presence of the detailed mechanisms and patterns we observe?  How much is chance, and how much is necessity?  A defining feature of the recent Systems Biology movement is the tendency to explain biological organization in terms of design principles, i.e. strategies for achieving ends dictated by natural selection.  Following this approach I will discuss two examples of how selection for the ability to perform diverse tasks imposes constraints on biology, constraints that justify the need for complex patterns of organization that might otherwise seem arbitrary.  In one case I will talk about systems that implement robust pattern formation during animal development. In the other I will talk about stem cell systems, which underlie the development and/or maintenance of most tissues and organs, and which provide the context within which cancers arise.  In both cases, I will argue that approaching biology as a set of solutions to control problems provides more satisfying answers than are obtained by treating it as merely a complicated example of physics.  

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Additional Information

In Campus Calendar
Yes
Groups

Parker H. Petit Institute for Bioengineering and Bioscience (IBB), Bioengineering Graduate Program

Invited Audience
Undergraduate students, Faculty/Staff, Public, Graduate students
Categories
Seminar/Lecture/Colloquium
Keywords
IBB
Status
  • Created By: Colly Mitchell
  • Workflow Status: Published
  • Created On: Feb 4, 2014 - 10:31am
  • Last Updated: Apr 13, 2017 - 5:23pm