Chemical Biology Seminar

Event Details
  • Date/Time:
    • Monday March 10, 2014
      11:00 am - 12:00 pm
  • Location: MoSE Building, Room 3201A
  • Phone:
  • URL:
  • Email:
  • Fee(s):
    N/A
  • Extras:
Contact

M.G. Finn, PhD - faculty host

Summaries

Summary Sentence: "AApeptides: From Structure to Function" - Jianfeng Cai, PhD - University of South Florida

Full Summary: Chemical Biology Seminar - "AApeptides: From Structure to Function" - Jianfeng Cai, PhD - University of South Florida

"AApeptides: From Structure to Function"

Jianfeng Cai, PhD

Assistant Professor
Department of Chemistry
University of South Florida

The identification and development of sequence-specific peptidomimetics is of significance in bioorganic chemistry and chemical biology. A new class of peptidomimetics termed "AApeptides" was recently developed by our group. The synthesis of AApeptides can be conveniently achieved on the solid phase. Similar to other peptidomimetics, AApeptides are resistant to proteolytic degradation, and possess limitless potential to introduce chemically diverse functional groups. Moreover, they are able to fold into well-defined helical structures. The functions of AApeptides have also been recently explored. These include the rational design of AApeptides for the mimicry of the primary and secondary structure of bioactive peptides, as well as the development of one-bead-one-compound AApeptide combinatorial library for the identification of unnatural biomarkers or potential drug candidates.

Faculty host:  M.G. Finn, PhD

Related Links

Additional Information

In Campus Calendar
Yes
Groups

Parker H. Petit Institute for Bioengineering and Bioscience (IBB), Bioengineering Graduate Program

Invited Audience
Undergraduate students, Faculty/Staff, Graduate students
Categories
Seminar/Lecture/Colloquium
Keywords
No keywords were submitted.
Status
  • Created By: Colly Mitchell
  • Workflow Status: Published
  • Created On: Jan 31, 2014 - 6:11am
  • Last Updated: Apr 13, 2017 - 5:23pm