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Multiplex bioimaging of human biopsy

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Multiplex bioimaging of human biopsy samples with 35-marker at a time. Distinct tissue architectures reveal the difference between health and disease in an immune tonsil organ. In this example, spatial distributions of different cell types and tissue structure were visualized by different colors: B-cells (CD20), Extracellular matrix (Collagen), T-cells (CD3), Cytotoxic protein (Granzyme-B), Cell proliferation (Ki67).