99351 news 1246492800 1653584976 The Scientist , Jun 8 - You've unpacked your next-generation sequencing system and popped in some DNA or RNA. Five days later, you've sequenced 50 million tiny strings of nucleotides. Then what? Tolerating Mismatches USER: Nicholas Bergman, assistant professor of biology, Georgia Institute of Technology, Project: Mapping the transcriptome of anthrax-causing bacteria (Bacillus anthracis) and measuring gene expression levels Bergman's group uses Applied Biosystems' SOLiD gene sequencer, because it produces more data than do other new platforms... "It would take [an inaccuracy] and say this read is unmappable," Bergman says. The group needed a new algorithm that would tolerate these errors and move through vast amounts of data. (Full Story)

]]> 2009-07-02T00:00:00-04:00 The Scientist , Jun 8 - You've unpacked your next-generation sequencing system and popped in some DNA or RNA. Five days later, you've sequenced 50 million tiny strings of nucleotides. Then what? Tolerating Mismatches USER: Nicholas Bergman, assistant professor of biology, Georgia Institute of Technology, Project: Mapping the transcriptome of anthrax-causing bacteria (Bacillus anthracis) and measuring gene expression levels Bergman's group uses Applied Biosystems' SOLiD gene sequencer, because it produces more data than do other new platforms... "It would take [an inaccuracy] and say this read is unmappable," Bergman says. The group needed a new algorithm that would tolerate these errors and move through vast amounts of data.]]> 99361 image School of Biology - Biology

]]> 1275 http://www.the-scientist.com/article/display/55716/ http://www.biology.gatech.edu/faculty/nicholas-bergman/ http://www.biology.gatech.edu/ 1275