The paper, The Borderlands of Foldability: Lessons from Simplified Proteins, is a meta-analysis of six decades of protein research and reveals that ancient proteins may have been far more complicated and dynamic than previously thought. 

Recently published in the journal Trends in Chemistry, the study includes Georgia Tech researchers Lynn Kamerlin, professor in the School of Chemistry and Biochemistry and Georgia Research Alliance Vasser-Woolley Chair in Molecular Design, and Quantitative Biosciences Ph.D. candidate Alfie-Louise Brownless.

Co-authors also include Institute of Science Tokyo graduate student Koh Seya and Liam M. Longo, who serves as a specially appointed associate professor at Science Tokyo and as an affiliate research scientist at the Blue Marble Space Institute of Science.

The research has implications ranging from the origins of life and the search for life in the universe to cutting-edge medical innovation. “One of the biggest unanswered questions in science is how life first began,” says Kamerlin, who is a corresponding author of the study. “Understanding how the first protein-like molecules formed and what the earliest proteins may have been like is a key part of that puzzle.”

“Proteins power our bodies — and all life on Earth,” she adds. “Simply put, the evolution of proteins is the reason that we’re able to have this conversation at all.”

A Protein Folding Paradox

If proteins are the scaffolding of life, amino acids are the components that make up that scaffolding. “Today, an average protein is constructed from a chain of about 300 amino acids, involving 20 different types of amino acids,” Kamerlin shares. Proteins fold when these chains twist into a specific 3-dimensional shape, creating structures critical for biology.

However, while these folds are essential, exactly how a protein knows which way to fold remains a mystery. “We know that proteins didn’t just fold randomly,” Kamerlin shares, “because randomly trying all possible configurations would take a protein longer than the age of the universe.”

It’s a cornerstone problem in biological science called “Levinthal’s Paradox,” and highlights a fundamental mystery: Proteins fold incredibly quickly into very specific combinations — but like a sheet of paper spontaneously folding into an origami swan, researchers don’t know how proteins “choose” the folds they make.

“We can predict what a protein will look like, but can’t tell you how it got there,” Kamerlin adds. “That’s what we’re interested in exploring: how small early proteins developed into the complex proteins that support every living thing on today’s Earth.”

Simple Letters, Sophisticated Structures

Early proteins likely had access to just half of today’s amino acids. “About 10-12 amino acids were likely available on early Earth,” Kamerlin says. Like writing a story with just the letters “A” through “L,” researchers assumed that the ‘vocabulary’ proteins could build from such a limited amino acid alphabet would also be constrained.

“There is a language to protein folding,” Kamerlin explains. “That language is hidden in their structures. Our research is in trying to understand the rules — the grammar and vocabulary that dictate a protein fold.” 

The grammar they discovered was surprising: with a combination of creative techniques and environmental support, complex structures can arise from limited amino acid alphabets. 

“We found that it is possible to develop complex folds with very simple tools — and certain environments, like salty ones, can help support that,” Kamerlin shares. “Early proteins could also cross-link and associate, interacting like LEGO blocks to create more complex structures.”

Pioneering Proteins

Now, the team is conducting research in environments that could mimic conditions on early Earth — aiming to discover more about how these regions could have given rise to today’s complex proteins. “This aspect of our research also ties into the amazing space research happening at Georgia Tech,” Kamerlin says. “While we’re interested in understanding early life on Earth, our work could help inform where best to look for evidence of life beyond our planet.”

Kamerlin specializes in creating computer models that simulate possible scenarios – creating an opportunity to quickly and efficiently test many theories. The most compelling of these can then be tested by her collaborator and co-author at Science Tokyo, Liam Longo, in lab experiments. 

Protein folding is also at the forefront of medical innovation, ranging from diagnostic tools to cancer treatments and neurodegenerative diseases. “In the broader scope, we’re interested in discovering what we can design, what we can stress test, and what we can reconstruct with AI and other computational tools,” Kamerlin says. “Because if you can understand how proteins fold, you gain the ability to design them.”

Funding: NASA, the Human Frontier Science Program, and the Knut and Alice Wallenberg Foundation

DOI: https://doi.org/10.1016/j.trechm.2026.03.001

Georgia Tech's 11th annual Three Minute Thesis (3MT) competition took place on Tuesday, April 7th, where 12 scholars presented their innovative research in just three minutes to a non-specialist audience. After five preliminary rounds and Tuesday’s climactic competition, five graduate students were named winners and awarded research travel grants. 

“There is incredible power in alumni stories,” says Susan Lozier, dean of the College of Sciences and Betsy Middleton and John Clark Sutherland Chair. “It’s inspiring for students to speak with alumni in the workforce, hear how they landed their first jobs, and learn from their successes — and their setbacks.”

Claire Haskell (Mathematics 2025) recently obtained her first job with Deloitte and attended the dinner to offer perspective to current students.

“I want to reassure students still in school that, even in today’s uncertain times, getting a job is still really doable and not as out of reach as it seems. Meeting Tech alumni is a great first step.”

A Night of Networking

College of Sciences Career Educator Program Manager James Stringfellow and Director of Alumni Relations Leslie Roberts organized the annual signature career event.

“We put on events like this because we want all of our students ready for their next opportunity,” says Stringfellow.

Second-year psychology major Aleena Sange attended the event for the first time, and says she will be back next year. “The alumni were really helpful and reassuring,” says Sange. “I learned what employers look for in a resume and even received advice about contract negotiations and retirement.”

First-year astrophysics student Shannon Callahan agrees. “What struck me the most was hearing how well Georgia Tech prepares you for the workforce. It gave me a lot of confidence to hear that Tech alumni hit the ground running because they’re used to learning quickly.”

The evening included casual and more structured networking, with students rotating between tables on topics such as “Using AI in the Workplace,” “Handling Conflict,” and “How to Get Hired in the Real World.”

Janessa Rowland (Earth and Atmospheric Sciences 2014) works as an operations program manager for the Georgia Department of Natural Resources. She encouraged students to think beyond their major

“Sometimes an internship or class outside your major can open up the door for what you can do after Georgia Tech.”

Morgan Foreman (Psychology 2017), a technical product manager at IBM, offered encouraging insight: “People often tell you college is the best years of your life. Georgia Tech also sets you up for your dream life after college.”

2026 Internship Employer of the Year

During the festivities, Stringfellow announced Boehringer Ingelheim as the Internship Employer of the Year. The award honors a company that provides a high-quality learning environment for student interns. 

Arya Akbarshahi, a biochemistry major who spent a semester doing a co-op job at the company, presented the award, thanking the biopharmaceutical company active in both human and animal health for the learning experience provided.

“Co-oping at Boehringer Ingelheim was one of the most formative experiences in my training. From day one, I was trusted as a scientist, which allowed me to formulate hypotheses and execute experiments with direct implications for drug development strategy and decisions,”  says Akbarshahi. 

After presenting the award to Boehringer Ingelheim Senior Scientist Marc Sprouse, Akbarshahi also presented a surprise mentorship award to Sprouse.

“Marc was an exceptional mentor,” says Akbarshahi. “He challenged me to think critically about the biology, not just the assay, and consistently created space for me to take ownership and operate at a higher level.”

Sprouse accepted both awards and spoke of the benefits of working while still in school: “Getting real-world work experience while in school sets students up for success. I encourage all College of Science students to check out our website and apply for future co-ops and internships."

As during previous editions, this year’s conference featured more than two dozen scientists, engineers, policy experts, and thought leaders from Georgia Tech and beyond, illustrating how collaboration across fields – from science and engineering to public policy and international affairs – helps to advance strategic research priorities. 

“Frontiers is about discovery and connections across disciplines and generations,” says Susan Lozier, dean of the College of Sciences and Betsy Middleton and John Clark Sutherland Chair. “This edition provided an inspiring glimpse into the future of space exploration and the many ways Georgia Tech is contributing to research and missions seeking answers to what lies beyond our planet.” 

Commitment to Space

Space research is a key institutional priority at Georgia Tech, which is home to numerous academic and research programs in planetary sciences, robotics, mission design, space policy, and other areas. 

The recently established Space Research Institute (SRI) serves as the central hub connecting the broad range of space-related research across campus. Led by Jud Ready, who also serves as principal research engineer at the Georgia Tech Research Institute, SRI has expanded support for space research and commercialization through initiatives such as the CreationsVC Space Fellows Program and Centers, Programs, and Initiatives seed grant program.

SRI’s efforts are in line with Georgia Tech’s long-standing contribution to space exploration. Hundreds of Yellow Jacket alumni work in the space sector, including several graduates who are playing key roles in the Artemis program. To date, more than a dozen Georgia Tech alumni have traveled to space.

Exploring the Final Frontier

The conference featured a series of panels and discussions led by faculty and researchers from the Colleges of Sciences and Engineering as well as the Ivan Allen College of Liberal Arts. 

Sessions explored how researchers are studying the processes and conditions that support planetary habitability, seeking to answer one of humanity’s greatest questions: Does life exist beyond Earth? Speakers also examined how analog fieldwork in Earth’s extreme environments can inform space exploration, and how space research, in turn, can deepen our understanding of our own world.

Additional conversations centered on building better space missions through improved understanding of team and individual resilience, data collection, navigation, and the development of advanced technologies like the robots developed through the NASA LASSIE Project. 

Frontiers also highlighted Georgia Tech’s commitment to preparing the next generation of space scientists, engineers, and leaders. Student training and engagement were recurring themes throughout the day, with speakers emphasizing opportunities for student-led and student-run missions and research. A panel of Georgia Tech alumni shared their own STEM career journeys, challenging the idea of “one right path” to success — and acknowledging the resources and opportunities available at the Institute. 

A highlight of the conference was a fireside chat with Atlanta-native, retired U.S. Army Colonel and NASA Astronaut R. Shane Kimbrough (M.S. Operations Research 1998). Kimbrough, who spent a total of 388 days in space and performed nine spacewalks across three missions, reflected on his career and the evolution of spaceflight. He emphasized the expanding role of public-private and international partnerships in advancing ambitious goals, such as creating a permanent human outpost on the Moon. 

Policy and Public

The conference also explored how policy influences space discovery and innovation, with discussions touching on such issues as space security, access, governance, sustainability — and the influence of technology and science fiction on public perception and policy. 

Panelists described current policy frameworks governing outer space as struggling to keep pace with rapidly advancing technologies and expanding activities. According to these experts, increasing tensions among commercial, research, and recreational uses of space call for greater coordination among private and government entities to balance competing priorities while maximizing opportunities for innovation and exploration. 

The conference was punctuated by a networking lunch connecting attendees with Atlanta’s public astronomy community – including partners at several universities and the Georgia Tech Astronomy Club, which set up telescopes for attendees to safely observe the sun. Later that evening, the Georgia Tech Observatory hosted its Public Night, welcoming the broader Atlanta community to campus for telescope views of Jupiter, the Orion Nebula, and other celestial bodies. 

The Observatory Night was a fitting conclusion to a full day focused on Georgia Tech’s commitment and contributions to inspiring future generations of space explorers through research, education, and outreach. 

Experience the Frontiers conference in pictures on the College of Sciences’ Flickr account.

Released on April 7, the latest U.S. News report features the College's six schools, each of which earned top‑tier placements that reflect academic quality and peer reputation across disciplines.

Georgia Tech College of Sciences rankings

• Biological Sciences: No. 41 (tied)
  Tied with Mayo Clinic Graduate School of Biomedical Sciences; Northwestern University; Purdue University–West Lafayette; University of Arizona; University of California, Santa Barbara; and University of California, Santa Cruz.
   
• Chemistry: No. 20 (tied)
  Tied with University of California, San Diego.
   
• Earth Sciences: No. 29 (tied), up four spots
  Tied with Johns Hopkins University; Oregon State University; Texas A&M University–College Station; and Washington University in St. Louis.
   
• Mathematics: No. 26 (tied)
  Tied with Rice University; Rutgers University–New Brunswick; and the University of Washington.
   
• Physics: No. 22 (tied)
  Tied with Brown University; Duke University; Northwestern University; The Ohio State University; and the University of Wisconsin–Madison.
   
• Psychology: No. 39 (tied)*
  Tied with Michigan State University; Stony Brook University–SUNY; University of Arizona; University of California, Santa Barbara; University of Florida; and University of Iowa.

*Psychology rankings were carried forward from the most recent U.S. News social sciences rankings cycle.

These new rankings — based on peer perception surveys, as well as statistical indicators measuring faculty resources, research activity, and student outcomes — continue to highlight the College of Sciences’ breadth across core scientific disciplines and its role in advancing discovery, training future researchers, and supporting Georgia Tech’s research and mission.

Specialty Rankings: Chemistry and Mathematics

In addition to overall program rankings, Georgia Tech continues to earn national recognition in existing specialty graduate rankings within the College of Sciences, which carry forward from April 2023:

• Chemistry remains consistently ranked among the nation’s top programs, reflecting strength across sub‑disciplines and sustained research impact.
• Mathematics continues to earn recognition for both applied and theoretical strengths, supported by interdisciplinary connections across engineering, computing, and the sciences.

Chemistry specialty graduate programs

• Analytical Chemistry – No. 11
• Inorganic Chemistry – No. 20
• Physical Chemistry — No. 14
• Theoretical Chemistry — No. 18 

 Mathematics specialty graduate programs

• Analysis — No. 20 (tie)
• Applied Math — No. 16 (tie)
• Discrete Mathematics and Combinatorics — No. 5 (tie)

Full rankings: gatech.edu/about/rankings

This Thursday, April 2, the College of Sciences is hosting an inspiring look at the future of space exploration and life beyond Earth. Frontiers in Science: Advancing Space Exploration will convene leading scientists, engineers, policy experts, and thought leaders from across Georgia Tech and beyond to share research that’s guiding discovery and innovation. 

Published today in the journal Nature Communications, the paper “Trivalent Titanium in High-Titanium Lunar Ilmenite” confirms titanium in a reduced, trivalent state in a black, metal-rich lunar mineral called ilmenite. It’s a state only possible in low-oxygen environments, conditions researchers refer to as “reducing.”

“Models have suggested that these reducing conditions may have varied at different locations and times across the surface of the Moon,” says lead author Advik Vira, a graduate student in the School of Physics who recently earned his doctoral degree. “We hope our microscopy technique can be a valuable step in mapping and understanding the Moon’s 4.5-billion-year history.”

The team anticipates that their technique could be used on many of the lunar samples collected more than 50 years ago by the Apollo missions in addition to the Apollo Next Generation Samples — a group of lunar samples that have been stored under pristine conditions — and new samples from the planned Artemis missions, with Artemis II slated for launch this spring. The technique might also be applicable to samples collected from the far side of the Moon and returned in 2024 by the Chang’e-6 mission.

“The Moon holds clues not only to its own past, but also to the earliest eras of Earth’s evolution — history that has long since been erased from our planet,” Vira says. “This study is a step toward understanding the history of both and a reminder that there is still so much left to learn from the lunar rocks we’ve brought back to Earth.”

The School of Physics research team included corresponding authors Vira and Professor Phillip First; in addition to graduate student Roshan Trivedi; undergraduate students Gabriella Dotson, Keyes Eames, Dean Kim, and Emma Livernois; and Professor Zhigang Jiang, along with Institute for Matter and Systems Materials Characterization Facility Senior Research Scientist Mengkun Tian; School of Chemistry and Biochemistry Senior Research Scientist Brant Jones and Thom Orlando, Regents' Professor in the School of Chemistry and Biochemistry with a joint appointment in the School of Physics. 

The Georgia Tech team was joined by Addis Energy Senior Geochemist Katherine Burgess; Macalester College Assistant Professor of Geology Emily First; along with Lawrence Berkeley National Laboratory Research Scientist Harrison Lisabeth, Senior Scientist Nobumichi Tamura, and Postdoctoral Fellow Tyler Farr, who recently earned a Ph.D. from Georgia Tech’s George W. Woodruff School of Mechanical Engineering.

CLEVER research

The investigation began with a dark gray rock called a lunar basalt. Formed when ancient magma erupted on the Moon’s surface, minerals crystallized as it cooled — preserving key information in their structures. Billions of years later, the rock was brought to Earth by the 1972 Apollo 17 mission, where a small piece is now stored at Georgia Tech’s Center for Lunar Environment and Volatile Exploration Research (CLEVER), a NASA Solar System Exploration Research Virtual Institute (SSERVI) center led by Orlando.

As a NASA virtual institute, CLEVER supports researchers exploring lunar conditions and developing tools for the upcoming crewed Artemis missions, and provided the lunar samples for this research. The SSERVI also plays a critical role in training the next generation of planetary researchers: both Vira and Farr earned their Ph.D.s while on the CLEVER team.

“At CLEVER, we are very interested in understanding the impacts of space weathering,” Vira says. “We implemented modern sample preparation and advanced microscopy techniques to image samples at the atomic level, and were curious to apply it more broadly to the collection of Apollo rocks in the Orlando Lab. This sample caught our attention.”

“When we imaged an ilmenite crystal from the lunar basalt, what struck us first was how uniform and perfect the crystal structure was,” he recalls. “We found no defects from space weathering and instead saw an undamaged, pristine crystal — undisturbed for 3.8 billion years.”

To investigate further, the team analyzed small chips of the rock with Burgess, a member of the RISE2 SSERVI team and then a geologist at the U.S. Naval Research Laboratory. Using state-of-the-art electron microscopy and spectroscopy techniques, Vira determined the oxidation state of the elements in the ilmenite present. 

In spectroscopy measurements, each element leaves a distinct ‘signature,’ Vira explains. “When we brought our results back to Georgia Tech’s Materials Characterization Facility, Mengkun (Tian) noticed something unusual: the signature showed titanium might be present in the trivalent state.”

The presence of trivalent titanium had long been suspected in this lunar mineral. The team was intrigued. 

A new window into old rocks

With funding from Georgia Tech’s Center for Space Technology and Research (CSTAR), Vira returned to the U.S. Naval Research Laboratory to analyze additional samples. The results confirmed that more titanium was present than the mineral’s formula (FeTiO₃) predicts — indicating a portion of the titanium present was trivalent.

“That led me to place our measurements in terms of the broader geological context,” Vira shares. Working with First, Vira explored how ilmenite with trivalent titanium could help reconstruct the nature of ancient magmas from the Moon, especially the chemical availability of oxygen.

“Because its location on the Moon was noted during the Apollo mission, we know exactly where this rock is from, and we can determine how old the rock is,” he explains. “When coupled with our trivalent titanium measurements, we can use that information to estimate the reducing conditions for this specific region at the specific time our rock formed.”

If the upcoming Artemis missions return samples suitable for the team’s technique, these rocks could provide a new window into ancient lunar geology. The research also highlights that many lunar samples already on Earth could be reexamined to look for trivalent titanium.

“There is still so much to learn from the lunar samples we have already brought to Earth,” Vira says. “It’s a testament to the long-term value of each sample return mission. As technology continues to advance, this type of work will continue to give us critical insights into our planet and our place in the universe for years to come.”

DOI: 10.1038/s41467-026-69770-w

Funding: This work was directly supported by the NASA SSERVI under CLEVER. Researchers were also supported by the NASA RISE2 SSERVI and the Heising-Simons Foundation. Funding for collaborations between the U.S. Naval Research Laboratory and Georgia Tech for the investigation of lunar minerals was provided by the Georgia Tech Center for Space Technology and Research. Sample preparation was performed at the Georgia Tech Institute for Matter and Systems, which is supported by the National Science Foundation. This work utilized the resources of the Advanced Light Source, a user facility supported by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences, and was supported in part by previous breakthroughs obtained through the Laboratory Direct.

Amino acids also play a critical role commercially where they are manufactured and added to pharmaceuticals, dietary supplements, cosmetics, animal feeds, and industrial chemicals — an energy-intensive process leading to greenhouse gas emissions, resource consumption, and pollution.

A landmark new system developed at Georgia Tech could lead to an alternative: a commercially scalable, environmentally sustainable method for amino acid production that is carbon negative, using more carbon than it emits.

The breakthrough builds on a method that the team pioneered in 2024 and solves a key issue – increasing efficiency to an unprecedented 97% and reducing the bioprocess cost by over 40%. It’s the highest reported conversion of CO2 equivalents into amino acids using any synthetic biology system to date.

Published in the journal ACS Synthetic Biology, the study, “Cell-Free-Based Thermophilic Biocatalyst for the Synthesis of Amino Acids From One-Carbon Feedstocks,” was led by Bioengineering Ph.D. student Ray Westenberg and Professor Pamela Peralta-Yahya, who holds joint appointments in the School of Chemistry and Biochemistry and School of Chemical and Biomolecular Engineering. The team also included Shaafique Chowdhury (Ph.D. ChBE 25) and Kimberly Wennerholm (ChBE 23); alongside University of Washington collaborators Ryan Cardiff, then a Ph.D. student and now a Chain Reaction Innovations Fellow at Argonne National Laboratory, and Charles W. H. Matthaei Endowed Professor in Chemical Engineering James M. Carothers; in addition to Pacific Northwest National Laboratory Synthetic Biology Team Leader Alexander S. Beliaev.

"This work shifts the narrative from simply reducing carbon emissions to actually consuming them to create value,” says Peralta-Yahya. “We are taking low-cost carbon sources and building essential ingredients in a truly carbon-negative process that is efficient, effective, and scalable.”

Heat-Loving Organisms

The work builds on the cell-free technology the team used in their earlier study. “Previously, we discovered that a system that uses the machinery of cells, without using actual living cells, could be used to create amino acids from carbon dioxide,” Peralta-Yahya explains. “But to create a commercially viable system, we needed to increase the system’s efficiency and reduce the cost.”

The team discovered that bits of leftover cells were consuming starting materials, and — like a machine with unnecessary gears or parts — this limited the system’s efficiency. To optimize their “machine,” the team would need to remove the extra background machinery.

"Leftover cell parts were using key resources without helping produce the amino acids we were looking for,” says Peralta-Yahya. “We knew that heating the system could be one way to purify it because heat can denature these components.”

The challenge was in how to protect the essential system components from the high temperatures, she adds. “We wondered if introducing enzymes produced by a heat-loving bacterium, Moorella thermoacetica, might protect our system, while still allowing us to denature and remove that inefficient background machinery.”

The results were astounding: after introducing the enzymes, heating and “cleaning” the system, and letting it cool to room temperature, synthesis of the amino acids serine and glycine leaped to 97% yield — nearly three times that of the team’s previous system.

Scaling for Sustainability

To make the system viable for large-scale use, the team also needed to reduce costs. “One of the most costly components in this system is the cofactor tetrahydrofolate (THF),” Peralta-Yahya shares. “Reducing the amount of THF needed to start the process was one way to make the system more inexpensive and ultimately more commercially viable.”

By linking reaction steps so waste from one step fueled the next, the team devised a method to recycle THF within the system that reduces the amount of THF needed by five-fold — lowering bioprocessing costs by 42%.

“This decrease in cost and increase in yield is a critical step forward in creating a method with real potential for use in industry and manufacturing,” Peralta-Yahya says. “This system could pave the way for moving this carbon-negative technology out of the lab and onto the continuous, industrial scale."

Funding: The Advanced Research Project Agency-Energy (ARPA-E); U.S. Department of Energy; and the U.S. Department of Energy, Office of Science, Biological and Environmental Research Program.

DOI: https://doi.org/10.1021/acssynbio.5c00352

“I’m thrilled to see Professor Sherrill tackle this role for the coming 5 years. He understands the rapidly evolving opportunities to apply AI and data science approaches to the diversity of research conducted by Georgia Tech faculty and students, and has a strong agenda to help our researchers make the most of this explosive change in the research landscape.” Said V.P. of Interdisciplinary Research, Julia Kubanek. “He also has deep experience with team building and management which will position IDEaS favorably.”

As executive director, Sherrill will guide IDEaS’ current initiatives, which include the Microsoft CloudHub program that supports innovative applications in Generative Artificial Intelligence, and provide oversight and support for the joint College of Computing / IDEaS Center for Artificial Intelligence in Science and Engineering (ARTISAN), which provides  Georgia Tech faculty and research engineers expert support staff, needed cyberinfrastructure, software resources, and advice to assist faculty with projects using large data sets or using AI and machine learning to drive discovery.

Sherrill will also the lead the launch of a new strategic vision, emphasizing the Georgia Tech research community’s expertise in the development of AI and ML techniques and their application to problems in science and engineering, high performance computing, and academic software. Sherrill will focus on internal and external partnerships at IDEaS, creating new collaborative efforts in areas such as economics, policy, and the arts and humanities. He will also work to strengthen current connections across Georgia Tech’s Colleges, Interdisciplinary Research Institutes (IRIs), and the Georgia Tech Research Institute (GTRI).

“It’s a great honor to be named the next executive director of IDEaS,” said Sherrill.  “Georgia Tech has world-class faculty and students, and an unparalleled spirit of collaboration.  By bringing together faculty from across campus and working together with some of the amazing student groups, we can leverage the power of AI to accelerate our research and maximize our impact.  IDEaS will continue to run upskilling workshops to help our campus keep pace with the rapid changes in AI.”

Sherrill is an active promoter of education in computational quantum chemistry, as well as a strong voice for the benefits of open-source software for research acceleration. He was named Outreach Volunteer of the Year by the Georgia Section of the American Chemical Society in 2017, and he is the lead principal investigator of the Psi open-source quantum chemistry program.

Sherrill earned a B.S. in chemistry from MIT in 1992 and a Ph.D. in chemistry from the University of Georgia in 1996. From 1996-1999 Sherril was an NSF Postdoctoral Fellow at the University of California, Berkeley.

Sherrill is Fellow of the American Association for the Advancement of Science (AAAS), the American Chemical Society, and the American Physical Society, and he has been Associate Editor of the Journal of Chemical Physics since 2009. Sherrill has received a Camille and Henry Dreyfus New Faculty Award, the International Journal of Quantum Chemistry Young Investigator Award, an NSF CAREER Award, and Georgia Tech's W. Howard Ector Outstanding Teacher Award. In 2023, he received the Herty Medal from the Georgia Section of the American Chemical Society, and in 2024, he was elected to the International Academy of Quantum Molecular Science.

- Christa M. Ernst

Georgia’s forest industry has long been a pillar of the state’s rural economy. But in recent years, mill closures and shifting markets have put pressure on landowners, workers, and entire communities, particularly in south Georgia. A recently approved $8.9 million Georgia Forestry Innovation Initiative will help chart a new path forward, creating more value from Georgia’s abundant forest resources and expanding opportunities for the people and regions depending on them. 

“This year’s class is a truly impressive cohort,” said Paul R. Sanberg, FNAI, president of NAI. “I commend them on their incredible pursuits, and I’m honored to welcome them to the Academy.”

Recognizing NAI Senior Member Chandra S. Raman

Raman is a physicist, inventor, and technology entrepreneur whose work is helping shape the future of quantum sensing. As the Dunn Family Professor of Physics, he studies how atoms behave at extremely low temperatures and uses that knowledge to build new kinds of ultra-precise measurement devices.

Best known for the co-invention of chip‑scale atomic beam technology — a breakthrough that makes it possible to build tiny quantum sensors for navigation and timing — Raman and his team’s patented devices can operate where GPS fails. These inventions form the foundation for a new generation of manufactured quantum hardware, offering new capabilities for autonomous vehicles, aerospace systems, and national security.

To bring these technologies from the lab to real-world use, he founded 8Seven8, Inc.:

“By launching 8Seven8 as the first quantum hardware company in Georgia, we are creating high-tech jobs, building a skilled workforce pipeline, and seeding a quantum ecosystem in the Southeast that will see lasting economic benefits,” explains Raman. “We seek to establish the region as a player in the rapidly expanding quantum technology economy.”

He is the principal investigator for the Raman Lab, a Fellow of the American Physical Society, a frequent invited speaker at international conferences, and an advisor to national and space-based quantum initiatives. Raman holds six patents, including three issued U.S. patents and two licensed patents. Through his research, mentorship, and entrepreneurial leadership, he is working to advance scientific discovery and the development of practical technologies with lasting impact.

“This award is the culmination of years of effort in developing innovative approaches to bringing quantum sensing out of the lab,” says Raman. “The NAI is chock-full of wonderful inventors, and I am privileged to be among them. Through this award, I hope to bring useful inventions out of the lab and promote Georgia as a great place to be an entrepreneur.”

Recognizing NAI Senior Member Jason Azoulay

Azoulay is the Georgia Research Alliance Vasser-Woolley Distinguished Investigator in Optoelectronics and the principal investigator for the Azoulay Group. His research has pioneered the development of new classes of functional materials and made field-leading advancements in core areas spanning:

· Homogeneous catalysis applied to polymer synthesis

· Electronic, photonic, spin, magnetic, and quantum materials

· Device fabrication and engineering

· Chemical sensing for environmental monitoring

· Synthesis, application, and engineering of high-performance polymers across multiple technology platforms.

Azoulay has demonstrated new classes of organic semiconductors with infrared functionality by exploiting new light-matter interactions, analyzing emergent transport phenomena, and understanding device physics, functionality, and engineering considerations. His work has resulted in nine issued patents and many additional applications.

Additionally, he is the principal investigator for two multi-million-dollar National Science Foundation (NSF) grants. The first grant harnesses an underused part of the electromagnetic spectrum for energy sensing, manufacturing, and more. His team creates organic polymers that can efficiently convert infrared radiation into electrical signals and develop the materials into functional devices. The initiative is the NSF’s principal vehicle to continue the momentum of the decade-long Materials Genome Initiative and takes advantage of the power of machine learning and chemical synthesis to develop new functional materials.

The second NSF-funded program develops CP-based optical and electrical sensing platforms that operate in complex aqueous environments and enable the detection and discrimination of challenging analytes known to negatively impact human, biota, and ecosystem health.

Azoulay holds a joint appointment in the School of Materials Science and Engineering and leads Georgia Tech’s Center for Organic Photonics and Electronics (COPE). COPE-affiliated faculty create flexible organic photonic and electronic materials and devices that serve the information technology, telecommunications, energy, and defense sectors.

"The IOP has a long and distinguished history as the primary learned society and professional body for physicists in the U.K., Ireland, and beyond,” says Kamerlin, who completed both a Master of Natural Sciences and a Ph.D. in Theoretical Organic Chemistry from the University of Birmingham in the United Kingdom. “As a society, it plays an important role in building community, promoting science, advancing advocacy for our discipline, and supporting the next generation of physicists.”

Kamerlin joins a list of distinguished Fellows that includes legendary physicists such as Dame Jocelyn Bell Burnell, a preeminent astrophysicist responsible for the discovery of pulsars (a previously unknown type of star) and the first female president of the IOP.

“It is a great honor to be awarded Fellowship of the IOP, particularly as women more broadly remain vastly underrepresented in physics,” Kamerlin says. “I look forward to giving back to the physics community, supporting the mission of the society, and working to remind the next generation that physics is for everyone."

About Lynn Kamerlin

Kamerlin’s research in computational biophysics is at the intersection of chemistry and biology, where she focuses on investigating fundamental physical chemistry and using computational tools to understand complex biomolecular problems. Currently, she is interested in leveraging machine learning tools to design new enzymes and in predicting protein structures and behaviors using large language models.

In addition to her roles at Georgia Tech, Kamerlin is a senior editor of Protein Science, the editor-in-chief of Electronic Structure, and was named a 2025-27 visiting professor at Lund University. She was also named a Fellow of the Royal Society of Chemistry, received the 2026 Inspiration and Resilience Award from the Biochemical Society, and was the 2023 Biophysical Society Theory & Computation Subgroup Mid-Career Award Winner.

“Support from the RCSA is much appreciated right now to maintain our research productivity and pedagogic service to our student body,” says Agarwal. “The focus of RCSA extends beyond scientific research to include student success, which is in excellent concert with Georgia Tech’s mission.”

Agarwal, who joined Georgia Tech in 2017, holds joint appointments in the Schools of Chemistry and Biochemistry and Biological Sciences. His research group studies natural products — small molecules created by living organisms — to understand how they are made and explore potential uses. In 2021, Agarwal was named an RCSA Cottrell Scholar in recognition of his study of natural products found in oceans and his efforts to develop new curricula for undergraduates related to this research.

His additional professional recognitions include the NSF CAREER Award, the American Society of Pharmacognosy Matt Suffness Young Investigator Award, the Camille Dreyfus Teacher-Scholar Award, and the Sloan Research Fellowship.

The new initiative was sparked by ongoing research at Georgia Tech — and a Yellow Jacket connection: when Postdoctoral Research Fellow Hannah Youngblood’s work on exfoliation glaucoma (XFG) was featured by the BrightFocus Foundation, it caught the attention of Jennifer Rucker, an Alabama resident who was diagnosed with XFG several years ago.

Excited that the research could change outcomes for people like her — and proud that it’s happening at her husband Philip Rucker’s, EE 72, alma mater — Jennifer Rucker reached out to Youngblood and her advisor, School of Chemistry and Biochemistry Professor and Kelly Sepcic Pfeil, Ph.D. Chair Raquel Lieberman. 

“As the wife of a Georgia Tech graduate and an individual with pseudoexfoliation glaucoma, I was inspired to support the scientists whose efforts may help me and others,” Jennifer Rucker says. What followed was a meaningful dialogue and a shared sense of purpose — and the creation of the Georgia Tech Glaucoma Research Fund (Wreck Glaucoma! Fund). 

“It meant so much that Jennifer took the initiative to reach out to learn more about our research,” says Lieberman. “Moments like this remind me how deeply meaningful it is to connect with people in the broader community who are navigating glaucoma. Opportunities for such personal connections are rare, but they inspire and further motivate us to achieve our lab’s mission to improve the lives of individuals suffering from blindness diseases.”

A Personal Connection

Youngblood’s interest in glaucoma research also stems from a personal connection: her father was diagnosed with glaucoma as a young adult. Now, Youngblood studies the genetic and molecular factors behind XFG in the Lieberman research lab. 

“XFG is an aggressive form of the disease with no known cure,” Youngblood says. While scientists know that XFG is the result of abnormal accumulation of proteins in the eye, current treatments only address symptoms rather than treating the root cause of the disease.

“We know XFG is driven by protein buildup, but we still don’t know why it happens,” she explains. “My work studying specific genetic variants aims to uncover this.” 

The Genetics of Glaucoma

In particular, Youngblood is researching the role of LOXL1, a protein that plays a role in soft tissue throughout the body, including the eyes.

“Research has shown that people with variants in the genes responsible for this protein are more likely to have XFG,” she says. “That made me curious to see if the variants might be impacting the structure of the LOXL1 protein itself and how those variants might lead to disease.”

Youngblood is currently testing her theory in the lab. “My hope is that new insight into proteins like LOXL1 will bring us closer to treatments that address XFG at its source,” she says. “The new Georgia Tech Glaucoma Research Fund is a tremendous step forward in making that hope a reality.”

Support the Georgia Tech Glaucoma Research Fund

Please visit the Glaucoma Research Fund support page to give to this specific program. To discuss additional philanthropic opportunities, please contact the College of Sciences Development Team: development@cos.gatech.edu

Your investment ensures that these scholars and researchers have world-class resources, facilities, and mentors to excel in this critical work. Thank you for helping us shape the future.

The project, inspired by an Atlanta Science Festival event hosted by School of Chemistry and Biochemistry Assistant Professor Andrew McShan, develops an innovative outreach and teaching module around nuclear magnetic resonance (NMR) techniques, and is designed for easy adoption in introductory chemistry and biochemistry courses. 

Published earlier this year in the Journal of Chemical Education, the study, “Automated Chemical Profiling of Wine by Solution NMR Spectroscopy: A Demonstration for Outreach and Education” was led by a team from the School of Chemistry and Biochemistry including lead author McShan, Ph.D. students Lily Capeci, Elizabeth A. Corbin, Ruoqing Jia, Miriam K. Simma, and F. N. U. Vidya, Academic Professional Mary E. Peek, and Georgia Tech NMR Center Co-Directors Johannes E. Leisen and Hongwei Wu.

“NMR is one of the most widely used analytical tools in chemistry and the life sciences, and Georgia Tech hosts one of the most cutting-edge NMR centers in the world,” McShan says. “Our study shows that you don’t need advanced training to appreciate how powerful tools like NMR work and how those tools are used in research.”

All materials, tutorials, and data are freely available via online tutorials and a YouTube video, enabling educators to replicate or adapt the activity even in settings with limited access to NMR facilities.

Wine sleuthing at the Atlanta Science Festival

From families with K-12 students to undergraduates to adults with no prior chemistry experience, nearly 130 visitors explored wine chemistry at the Georgia Tech NMR Center during the Atlanta Science Festival event. With McShan’s guidance, they identified and quantified more than 70 chemical components that influence wine taste, aroma, and quality by analyzing the chemical composition, structure, and dynamics of molecules.

Taking on the role of wine investigators (a real-world application of NMR), the group investigated examples of wine fraud, learning to identify harmful additives like methanol, antifreeze, and lead acetate – additives that played roles in both historical and modern wine scandals.

“By connecting the science to something familiar like wine, we were able to spark curiosity and excitement across age groups,” says McShan. “This a framework for how complex analytical techniques can be made inclusive, interactive, and inspiring whether in the classroom or at a science festival.”

Science for all

The study underscores the potential of NMR and other powerful technologies as outreach opportunities – from engaging the public to better teaching undergraduate students.

“After the event, adults said they learned how chemical composition affects wine characteristics and how NMR is used in research and industry,” McShan says. “Younger participants learned key concepts about wine composition and found benefits from the sensory elements, like watching the spectrometer in action.”

They aim to use these takeaways to continue developing outreach tools. “My end goal is to develop NMR into a practical teaching tool by grounding the technique in real-world examples,” adds McShan. “Using this approach is a clear avenue to introducing the general public to the world-class instruments used by researchers at Georgia Tech and exposing undergraduate students to the powerful analytical techniques they are likely to encounter throughout their careers.”

Funding: National Science Foundation

“It’s literally life or death sometimes,” says Brandon Brigner, a fall 2025 biochemistry graduate now pursuing a master’s in chemistry.

Four Georgia Tech students share their experiences on the front lines of medicine as EMTs, including Brigner; Lianna Homrich, a fourth-year biology major; Daeun “Esther” Lee, a third-year biomedical engineering major; and Krishna Monroe, a third-year neuroscience major. Brigner, Homrich, and Monroe work as EMTs on ambulances while Lee serves as a technician at Emory University Hospital Midtown. Each plans a career in medicine and serves on the leadership team for EMS at Tech, a student organization dedicated to expanding access to and knowledge of emergency medical services on campus.

Why become an EMT?

All four agree that EMT work offers unmatched medical experience.

“You can show up on someone’s worst day and immediately make a difference,” says Lee.

Homrich started exploring EMT work after realizing she needed clinical hours for the pre-health track. “The adrenaline and lifesaving aspect appealed to me. I knew I’d learn so much from living the hands-on side of medicine.”

Brigner began working as an EMT in high school. “I wanted to get started on my pre-med journey,” he explains. “Becoming an EMT is one of the most powerful medical experiences you can have — and it’s definitely solidified my decision to pursue medicine as a career.”

What’s the job like?

Monroe first joined an ambulance crew with American Medical Response in DeKalb County and now works for Grady Health System. “At a basic level, our job is to stabilize patients and get them to the hospital safely,” says Monroe.

Brigner explains that most ambulance EMTs split time between emergency calls, special events, and transfers. “It can be intense,” he says. “When everything goes well, you can seriously change someone’s life trajectory.”

Monroe adds that there is no typical shift on an ambulance. “We’ve had anything from people shot in the chest to someone struggling to breathe to someone experiencing abdominal pain because they are hungry. You respond where the public needs you.”

What do you like best about being an EMT?

Homrich appreciates the people. “You’re on a truck for 12 hours with career paramedics who spend their lives saving others. Many are former military; I learn something new every shift. They’re heroes.”

Lee values the teamwork she finds at the hospital. “Usually when something very high acuity comes in, like a cardiac arrest, you have everyone in the emergency room acting as a team. We’re doing chest compressions, checking in with each other, and switching out when needed. Everyone is there in this very stressful time, working together to save someone’s life.”

How does EMT work prepare you for careers in medicine?

EMT work offers solid medical experience and critical soft skills. “You’re making decisions about real patients,” says Monroe. “You have your own patient, sometimes with no help for 30-45 minutes, depending on how long it takes to get to the hospital. It’s the best clinical experience you can get.”

Lee adds, “It teaches creativity, problem solving, and composure under pressure — skills you can’t learn from a textbook. You learn to stay composed in chaos.”

How do you balance school and work?

All four agree that it takes a lot of organization and discipline. “Having a good calendar system is key, and strategically scheduling classes really helps,” says Homrich. “I’ve definitely fallen into traps where I get really into EMS — picking up cool events or overnight shifts for bonuses — but I’ve learned to make schoolwork a priority. Academics come first.”

Lee primarily works weekends to accommodate her school schedule. “I work 7 a.m. to 7 p.m. on Saturdays and Sundays,” she says. “I get most of my studying done during the week.”

What kind of training does it take to become an EMT?

Monroe is an Advanced EMT while Brigner, Homrich, and Lee hold the EMT Basic designation. Training includes coursework, skills testing, and clinical ride-alongs. To become an EMT, students must complete training, earn National Registry EMT certification, and apply for a state license.

“The real learning happens during clinicals or ‘third rides,’ where you ride along as the third person on the truck,” says Homrich.

Monroe estimates that he has spent more than 600 hours studying and training to earn both certifications.

Can you describe a meaningful moment in your EMT career?

Beyond the life-saving thrills, these students encounter moments that stay with them forever.

Brigdon remembers an incident from his very first day as an EMT:

“We were transporting a patient up from the depths of the D.C. subway. After putting him on the gurney, we took the escalator instead of the elevator. The fire crew saw us and immediately let us know that wasn’t the right move. Listening to their angry feedback put into perspective how serious this job is and the life-changing implications of doing it right. That moment taught me that every decision matters.”

Homrich remembers leading an “honor walk,” a ceremony to honor organ donors and support their families, for a deceased teenage patient being transferred for organ donation:
“At 19 years old, I wheeled a son away from his mother for the last time, knowing she’d never see him again. It was heavy but also meaningful because his sacrifice would create so much life. That moment reminded me how much trust people place in us — and the importance of what we do.”

What is Emergency Medical Services at Tech (EMS at Tech)?

A student organization dedicated to improving emergency medical care on campus, the club partners with Grady EMS and the Georgia Tech Police Department to respond to medical emergencies, lead CPR and first aid classes, and provide clinical opportunities for members.

“EMS at Tech is a community where you can nerd out and share your passion for emergency medicine,” says Homrich, the club’s vice president. “When you’re with friends at lunch, no one wants to hear about applying a tourniquet for an arterial bleed. But at EMS at Tech, everyone is an emergency medicine enthusiast who wants to share experiences.”

Last semester, the group trained more than 160 students, faculty, and staff in CPR/AED and supported campus events like Homecoming and Halloween. EMS at Tech also guides students pursuing EMS certifications and helps administer the Todd Family Fund EMS Scholarship, which covers tuition for Grady EMS Academy classes.

“The selection committee received more than a dozen proposals that push the boundaries of AI-enabled science and encourage collaboration across units. I look forward to seeing the great science, strong results, and successful future external funding enabled by these seed grants,” says Dimitrios Psaltis, professor in the School of Physics and director of the AI4Science Center. 

Launched earlier this semester, the center promotes cross-disciplinary research on AI tools that address scientific challenges. The following three proposals were selected by the center based on their scientific goals, extent of interdisciplinary collaboration, and potential for outside funding: 

Spring 2026 AI4Science Center Seed Grant Recipients  

Graph Foundation Models for Protein Conformational Dynamics | School of Chemistry and Biochemistry 

• PIs: Professor Peter Kasson, School of Chemistry and Biochemistry; Professor JC Gumbart, School of Physics; Assistant Professor Amirali Aghazadeh, School of Electrical and Computer Engineering
• Graduate student: Jeffy Jeffy
• Team statement: “The AI4Science Center’s seed funding will allow us to complete and test a prototype of our new deep learning architecture for protein dynamics. We're super excited about the project and happy that this gives us support to pursue our new idea.”

Combinations of Verified AI and Domain Knowledge for New Insights in Theoretical Physics | School of Physics

• PIs: Assistant Professor Aishik Ghosh, School of Physics; Professor Vijay Ganesh, School of Computer Science
• Graduate student: Piyush Jha
• Team statement: “This seed funding gives us an opportunity to connect two fields in a way that could transform our approach to certain problems in theoretical physics.”

Harnessing the Manifold Geometry of Neural Representations for Robust LLM Safety | School of Psychology 

• PIs: Assistant Professor Audrey Sederberg, School of Psychology; Assistant Professor Pan Li, School of Electrical and Computer Engineering
• Graduate student: Ruixuan Deng
• Team statement: “Our project injects insights from human neuroscience directly into AI safety algorithm design, allowing us to move beyond black-box approaches toward more interpretable and principled safety mechanisms. By closing the loop, these computational models will also provide new feedback and insights for neuroscience.”

“The School of Chemistry and Biochemistry is thrilled to see that Neha Garg is included in the current WCC Rising Star cohort,” says School of Chemistry and Biochemistry Chair and Professor Vicki Wysocki. “She is richly deserving of this award, given her excellent work on the interactions between eukaryotes (e.g., humans) and the microbiome.”

Garg obtained her Ph.D. from the University of Illinois Urbana-Champaign and conducted postdoctoral research at UC San Diego (UCSD)'s Skaggs School of Pharmacy and Pharmaceutical Sciences. She has been at Georgia Tech since 2017.

“This award is a tremendous source of personal pride as it acknowledges my lab’s hard work in the field of microbial chemistry,” says Garg. “It’s especially meaningful that it's a WCC award because it serves as a powerful platform for me to inspire young women.”

She adds that visibility remains essential for advancing women in STEM.

“Imposter syndrome is real, so awards like this are important for women in science,” explains Garg. “I’m grateful this recognition exists, and I’m proud and happy to be honored.”

As part of the Rising Star Award, Garg will be honored at a WCC luncheon and deliver a scientific talk highlighting her career path and current research at the ACS Spring 2026 Meeting in March.

Chemical communication and connection

Garg’s lab studies the chemistry that underlies crosstalk between the human microbiome and its host. The microbiome includes vast communities of bacteria living on and inside the body — from the skin and mouth to the gut, reproductive system, and lungs. Her group examines how these microbes and human tissues exchange information through small molecules.

“Our work aims to understand the chemistry of collaboration between the microbiome and its host,” says Garg. “We focus on the lungs and airways, studying how epithelial cells and microbial communities interact through nutrients and microbial compounds. These molecules form a chemical dialogue, and my lab builds models to decode and investigate it.”

By mapping this communication network, Garg hopes to shape future therapeutic strategies.

“Understanding collaboration between the microbiome and the host will help develop microbiome-targeted therapies,” she explains. “These therapeutics could prevent respiratory infections, promote the growth of beneficial bacteria, limit harmful bacteria, or influence host tissues in ways that improve health.”

Her work also extends to marine systems. Garg’s team studies similar chemical interactions between microbes and corals, offering insight into ecosystem resilience and ocean health.

Garg was co-nominated by Pieter Dorrestein, professor at UCSD’s Skaggs School of Pharmacy and Pharmaceutical Sciences, and Bradley Moore, distinguished professor of marine chemical biology and director of the Center for Marine Biotechnology and Biomedicine at UCSD’s Scripps Institution of Oceanography. Moore also serves as a distinguished professor at the UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences.

“She’s a multidisciplinary wizard leading a revolution in functional metabolomics,” says Moore. “Neha gives me great hope for a better tomorrow in science.”

“Neha is a remarkable scientist taking on deeply compelling questions in metabolic communication,” adds Dorrestein. “Her leadership, integrity, and commitment to mentorship make her a true role model for emerging scientists.”

Awards and accolades

Garg has earned numerous honors throughout her career, including the Royal Society of Chemistry's 2024 Natural Product Reports Emerging Investigator Lectureship Award, the 2023 ACS Academic Young Investigator Award from the Division of Organic Chemistry, Georgia Tech’s 2022 Junior Faculty Teaching Excellence Award, and a 2021 NSF CAREER Award. While working on her Ph.D. at the University of Illinois Urbana-Champaign, she received the Anne A. Johnson Work Award for Excellence in Biochemistry, which recognizes one female student per year for excellence in Ph.D. thesis research.

Culture and community at Georgia Tech

Garg credits her experience at Georgia Tech — and the Institute’s strong support of women in STEM — for shaping her path as a scientist and mentor. She praises the collaborative environment, helpful colleagues, and the number of women in leadership roles. Garg also appreciates the work of Georgia Tech organizations such as Women+ in Chemistry and the Center for the Study of Women, Science, and Technology.

“Georgia Tech provides a supportive, collegial, and respectful environment where women in STEM can thrive and truly make a difference,” says Garg.

“We are thrilled to have an official Ambassador Program featuring a group of students ready to help with special events and recruiting activities,” says Academic Program Manager Ashley Edwards, who created the program. “Events become much more meaningful when alumni and prospective students can speak with actual students who provide a real-world perspective about life at Georgia Tech.”

The ambassadors will be busy, says Edwards. They will play a key role in recruitment activities, including the bi-weekly It’s All About Science and Math event where prospective students visit campus for an overview of the College, enjoy lunch with faculty and students, and even sit in on a class. Ambassadors will also help host admitted student events, such as the Explore Science and Math Open House, participate in alumni engagement events, and assist with career education programs. 

“Being an ambassador is a chance to share my experiences and help others find their place here,” says Meghan Hamrick, a third-year chemistry major on the pre-health track. “I want to give back to the Institute that has given so much to me.”

Ambassadors will serve as a direct link for prospective students seeking personalized insight.

“Talking with a current student who participates in things they are interested in, like marching band, intramural soccer, or living in our Explore Living Learning Community, makes it real for prospective students. It’s a powerful connection,” explains Edwards.

“I hope I can be a useful resource. I think my experiences with neuroscience, study abroad, and working in the Housley Lab will resonate with future students,” says Inara Sheeraz, a third-year neuroscience major.  

Anja Govednik, a second-year physics major, looks forward to talking up her major. “I’d love to answer questions about physics — there’s so much more than most people realize!”

Representing the College

The ambassadors were selected based on GPA, short essay questions, campus involvement, and, for the finalists, a one-minute video introduction.

“We had more than 85 amazing students apply, so choosing was hard,” says Edwards. “We wanted a broad array of students, including transfer students, undergraduate researchers, student leaders, athletes, work-study students, and students from each major.”

She adds, “Most importantly, we looked for students who want to help, are passionate about science and math, really love Georgia Tech and the College of Sciences, and are excited to get other people to love the Institute as much as they do.”

Edwards is pleased to have the program up and running. “It’s a win-win. Not only will it showcase our strengths and the human side of the College of Sciences, but it will also help our student ambassadors. They’ll gain resume-worthy experience, connect with alumni, and engage with prospective students and parents. Plus, ambassadors will have opportunities to work closely with our deans and learn more about the College beyond academics.”

Meet the 2025 College of Sciences ambassadors: 

Ameera Alam, Psychology; Agastya Arora, Mathematics; Walker Bailey, Mathematics/Economics; Jayanna Baptiste, Biology; Alison Bolaños, Neuroscience; Laurel Bourg, Physics; Giuli Capparelli Sanabria, Biology; Pallavi Dokka, Neuroscience; Anjali Ganapathiraju, Biology; Anja Govednik, Physics; Meghan Hamrick, Chemistry; Britney Huynh, Biology; Ava-Elizabeth Jacoby, Psychology; Meghana Kesari, Neuroscience; Melody Lee, Computer Science/Mathematics; Larissa Martin, Astrophysics; Andrea Ninh, Biology; Malavika Niverthi, Neuroscience; Lea Setton, Psychology; Inara Sheeraz, Neuroscience; Nidhi Shenoy; Biochemistry; Deandra Smith, Neuroscience; J’Avani Stinson, Biology; Ishita Sukul, Biology; and Ria Vittal, Biochemistry.

Chirality, a property where structures have a distinct left- or right- “handedness,” allows natural semiconductors to move charge and convert energy with high efficiency by controlling electron spin and the angular momentum of light. A new study has revealed that many conjugated polymers, long considered structurally neutral, can spontaneously twist into chiral shapes. This surprising behavior, overlooked for decades, could pave the way for development of a new class of energy-efficient electronics inspired by nature.

The research, a collaborative project that included researchers from the University of Illinois Urbana-Champaign, Georgia Institute of Technology, University of North Carolina, and Purdue University was recently published in the Journal of the American Chemical Society.

“Many molecules essential to life are chiral,” said Ying Diao, professor of chemical and biomolecular engineering at Illinois, who led the project. “The question that has remained a really a big fascination across the field is how chiral symmetry breaking happens in the first place: that is how life selects one handedness over the other. Our work mainly focuses on the origin of chirality: why chirality spontaneously emerges in absence of any chiral sources.” 

To answer this question, the team tested 34 different conjugated polymers. Each polymer was dissolved in a solvent, then the researchers gradually increased the polymer concentration to observe whether liquid–liquid phase separation (LLPS) occurred. When LLPS was detected, they used circular dichroism spectroscopy to analyze the samples, revealing a strong correlation between phase separation and the emergence of chirality. The researchers refer to this phenomenon as spontaneous chiral symmetry breaking.

They found that approximately two-thirds of the polymers spontaneously formed chiral structures when their concentration in the solution increased.

“That took our community by surprise, because conjugated polymers have been studied for half a century,” Diao said. “These new chiral helical states of matter have basically been hiding in plain sight.”

To understand why some of the polymers developed chirality while others did not, Illinois chemistry professor and senior co-author Nicholas E. Jackson applied machine learning to analyze molecular features across the polymer library. The analysis, later backed up by additional testing, revealed that polymers with longer molecular chains were more likely to form chiral assemblies. Unexpectedly, the researchers also found that the presence of oxygen atoms in the side chains was a strong predictor of chiral behavior.

“Machine learning uncovered hidden patterns across dozens of conjugated polymers, relating subtle chemical details to chiral phase formation,” Jackson said. “Such insights would have been very difficult to derive by human intuition alone.”

Diao noted that the discovery not only deepens our fundamental understanding of chiral emergence but also holds significant technological promise. In nature, chiral systems – such as those involved in photosynthesis – enable highly efficient electron transport. Looking ahead, Diao said that mimicking this behavior could lead to major performance gains in electronic devices and innovation of new device types.

“We are thinking about using chirality to control conductivity – for example, in transparent conductors for phones or in solar cells that could be more stable and efficient,” she said. “In our computers, electrons bounce around and heat is a big problem. But if we make chiral versions, we think charge transfer could be extremely efficient, just like in nature.”

“What’s nice about this is, this is not the end of the story,” said Georgia Institute of Technology chemistry professor John Reynolds, a senior co-author on the study. “This work provides guidance to polymer scientists in the field for studying the many, many conjugated polymers that have been synthesized over the years, and for designing new polymers with enhanced properties.”

This study was supported by the U.S. Office of Naval Research, the Air Force Office of Scientific Research, the Molecule Maker Lab Institute, and the National Science Foundation. Polymers for the study were provided by Reynolds, University of North Carolina chemistry professor Wei You, University of Illinois chemistry professor Jeff Moore, and Purdue University chemistry professor Jianguo Mei.

In addition to her appointment in Chemical & Biomolecular Engineering, Diao is a full-time faculty member at the Beckman Institute for Advanced Science and Technology, holds a faculty appointment with Chemistry in the College of Liberal Arts & Sciences, and is affiliated with Materials Science & Engineering in The Grainger College of Engineering. In addition to his appointment in Chemistry, Jackson is a group leader at the Beckman Institute and affiliate faculty member in the departments of Chemical & Biomolecular Engineering and Materials Science & Engineering.

The paper, "Ubiquitous Chiral Symmetry Breaking of Conjugated Polymers via Liquid Liquid Phase Separation," is available online at https://pubs.acs.org/doi/abs/10.1021/jacs.5c07995

With this collaboration, eligible students who graduate with a bachelor’s degree from Georgia Tech will be able to enroll in the School of Nursing’s Master of Nursing (MN) program.  

Emory’s MN program is an entry-to-practice, pre-licensure degree program designed for students with bachelor’s degrees in other disciplines. Students who complete the 15-month program are eligible to sit for the National Council Licensure Examination and begin practice as a registered nurse. 

“We are excited to participate in a program that will develop future leaders in nursing,” said Steven Girardot, vice provost for Undergraduate Education and Student Success at Georgia Tech. “This direct pathway opens doors for our graduates to launch careers in nursing, living out our motto of Progress and Service in the most meaningful way.” 

The five-year partnership exemplifies the School of Nursing’s ongoing collaboration with metro Atlanta colleges and universities to prepare and empower high-caliber nurses. It represents another milestone in the school’s efforts to address workforce needs and advance nursing education.  

“Partnering with Georgia Tech represents another exciting step forward for nursing education,” said Linda McCauley, dean of the Nell Hodgson Woodruff School of Nursing. “Together, we’re expanding opportunities for future nurses and ensuring that our communities and health systems have the skilled professionals they need to thrive.”

Georgia Tech is the fourth local institution to partner with the School of Nursing, joining Spelman College, Agnes Scott College, and Oglethorpe University.  

The course, BIOS 4590, is a research project lab for senior biology majors that provides an opportunity for professors to share their expertise with students in a hands-on environment. In his class, Associate Professor Vinayak (Vinny) Agarwal, who holds joint appointments in the School of Chemistry and Biochemistry and School of Biological Sciences, aimed to introduce undergraduates to advanced bioinformatics tools through applied research using new-to-science raw data. 

The resulting paper, “Phylogenomic Identification of a Highly Conserved Copper-Binding RiPP Biosynthetic Gene Cluster in Marine Microbulbifer Bacteria,” which was recently published in ACS Chemical Biology, involves the historically understudied genus of Microbulbifer, a type of bacteria often associated with sponges and corals. These microbial communities are rich sources of natural products, small biological molecules often associated with medicine and drug discovery. 

"This class, and the resulting research, is a testament to the transformative power of hands-on learning,” says Susan Lozier, dean of the College of Sciences, Betsy Middleton and John Clark Sutherland Chair, and professor in the School of Earth and Atmospheric Sciences. “The success of this course — and the students’ remarkable achievement — reflects Georgia Tech's commitment to fostering curiosity, collaboration, and scientific rigor and to empowering the next generation of scientists and leaders."

Funded by Agarwal’s 2023 National Science Foundation CAREER grant and Camille and Henry Dreyfus Foundation Teacher-Scholar award, the class also received support from leadership in the College of Sciences, School of Biological Sciences, and School Chemistry and Biochemistry. The study’s lead author, graduate student Yifan (Grace) Tang, served as the class teaching assistant, and was funded in part by a Biochemistry and Biophysics Graduate Assistance in Areas of National Need fellowship. 

“The students in this class are working on important, novel work — this cohort worked with real genomic data that had never been sequenced before,” she says. “Typically, researchers might work with one or two genome sequences, but we provided students with 42 — this might be the first time anyone has looked at Microbulbifer at such a wide scope.” 

From classroom to publication

To prepare for the class, Tang worked alongside Laboratory Manager Alison Onstine, who manages the School of Biological Sciences teaching laboratory spaces, to sequence the Key West bacterial genomes.

“Our work in the Agarwal Lab is in natural product discovery. We focus on finding new pharmaceutical drugs through marine bacteria — but with a bioinformatics spin,” Tang explains. “We wanted to bring this type of experience to undergraduates, so we gave fully sequenced genomes to students and asked them to look for potential properties.” 

Throughout the class, students learned different techniques for analyzing bacterial genome sequences and extracting data with various tools — gaining both lab and computational skills through hands-on experiences, live demos, and troubleshooting sessions. 

“The highlight was showing students just how much we can learn about a bacterial genus, especially one that hasn’t been studied at this scale before,” Tang shares. “This is a growing field, so there are so many opportunities for students to make meaningful contributions while learning new skills.”

Empowering future students

For many students, it was their first time using these types of tools, but Agarwal says that it’s something they'll likely encounter in both industry and research. He sees this type of research experience as especially helpful for seniors, who are often deciding between entering the workforce or continuing their education.

“Bioinformatics is increasingly important for analyzing big data. Students need the ability to manipulate and understand data using computational tools, and this class plays an important role in familiarizing them with this process,” he shares. “Our goal is to demystify research and give students the confidence and tools for both graduate school and for the workforce after graduation.”

The class will be offered for a third time in Fall 2026. While the exact course of research hasn’t yet been decided, “we always aim for something new that can produce publication-quality research — students don’t repeat past year’s work,” Agarwal says. This recent cohort of students built on the success of 18 undergraduates who took the class in 2023, who also published a paper. “This course truly underscores Georgia Tech’s commitment to pioneering meaningful undergraduate experiences — no other peer institution I know of is exposing undergraduates to bioinformatics at this level.”

Funding: NSF CAREER and the Dreyfus Foundation

“A university’s success is measured and reflected in the achievements of its alumni,” notes Cabrera. “It is a great source of pride for Georgia Tech to recognize these College of Sciences alumni and their impressive accomplishments — across the world and at Georgia Tech.”

Six alumni — one from each School — received the Distinguished Alumni Award:

School of Biological Sciences

Jack McCallum, Applied Biology 1966, a surgeon-turned-entrepreneur and educator, was honored for his contributions to medicine, business, and philanthropy. He joked that medical school was easier than Georgia Tech.

School of Chemistry and Biochemistry

Kelly Sepcic Pfeil, M.S. Chemistry 1992, Ph.D. Chemistry 2003, a scientific leader in flavor and sweetener technology, was recognized for her global career and support of women in chemistry. She thanked Tech for supporting her as a young working mother who traveled globally for business while earning her graduate degrees.

School of Earth and Atmospheric Sciences

Rutt Bridges, Physics 1973, M.S. Geophysical Sciences 1975, a pioneer in seismic software and climate solutions, author, and venture fund owner, was celebrated for his entrepreneurial success and philanthropy. His introduction revealed that he worked for $3.50 a day as a roustabout and well digger before Georgia Tech.

School of Mathematics

Frank Cullen, Math 1973, M.S. Industrial and Systems Engineering 1976,
Ph.D. Industrial and Systems Engineering 1984, a serial entrepreneur and longtime supporter of faculty research, was honored for his business leadership and philanthropic impact. He entered Georgia Tech at just 16 years old — and didn’t leave for 14 more years!

School of Physics

Nathan Meehan, Physics 1975, a globally recognized petroleum engineer, business leader, and educator, was celebrated for his technical leadership and commitment to early-career scientists. His introduction showcased his many professional accolades as well as his self-proclaimed status as the “best BBQ cook of his generation.”

School of Psychology

Margaret Beier, M.S. Psychology 1999, Ph.D. Psychology 2004, now chair of Psychological Sciences at Rice University, was honored for her research on lifelong learning and academic leadership. She thanked the faculty and researchers who inspired and supported her, enabling her to realize her dreams.

The evening also included two special honors:

The Young Scientist Award 

Kristel Bayani Topping, Ph.D. Physiology 2021, a principal researcher at The Home Depot, dedicated her win to her two young daughters and thanked her mentor School of Biological Sciences Professor Lewis Wheaton for helping her become a “better scientist and leader.”

The Impact Award 

John Clark Sutherland, Physics 1962, M.S. Physics 1964, Ph.D. Physics 1967, currently the dean of Science and Mathematics at Augusta University, was recognized for being an exceptional graduate whose sustained engagement, visionary leadership, and strategic support significantly advanced the College’s mission. Sutherland spoke about how far Georgia Tech has come since he was a student and the importance of continuing to invest in the Institute’s future through student support.

“This celebration marks a significant milestone for our College,” says Susan Lozier, dean of the College of Sciences and Betsy Middleton and John Clark Sutherland Chair. “Our alumni are not just a part of our history; they are central to our future. Their leadership, generosity, and engagement support our faculty and inspire our students.”

In her closing remarks, Lozier thanked alumni Paul Goggin, Physics 1991, and Charlie Crawford, Applied Mathematics 1971, for their help in creating the celebration as well as Leslie Roberts, director of Alumni Relations, for “her vision, persistence, and championship of an alumni recognition event.”

The awards presentation concluded with a rousing performance by the Georgia Tech Glee Club and a reception to celebrate the award winners.

“It was an amazing night recognizing eight incredible alumni who have made such a difference in the world,” says Roberts. “What struck me the most about this night was the humility of our honorees. In their speeches, they thanked Georgia Tech for launching their careers and recognized others for their efforts. They are truly an inspiration to the Yellow Jacket community.”

“Achieving this milestone reflects the generosity and deep commitment of our alumni, donors, and friends to advancing science education and research,” says Susan Lozier, dean of the College of Sciences and Betsy Middleton and John Clark Sutherland Chair. “We are energized by this momentum and grateful to everyone who has supported us through investment in our success as we continue to fundraise for key priorities such as endowed faculty positions, graduate fellowships, undergraduate scholarships, and innovative teaching and experiential learning.”

Sciences is the first Georgia Tech College to reach its goal. 

“This early success highlights the foundational and essential role of the sciences,” adds College of Sciences Director of Development Dan Warren. “The enthusiastic support from alumni, foundations, and corporate partners speaks volumes — reaching this milestone is a tribute to the transformative power of philanthropy and community.”

Philanthropy in action

The funds raised are already making a meaningful impact across the College, supporting students, faculty, and research. Campaign contributions are being invested in important initiatives such as:

• faculty endowments with an emphasis to support those in early and mid-career and in interdisciplinary areas;
• graduate student top-up fellowships to support recruitment of the best and brightest to our programs;
• need-based undergraduate scholarships to ensure an affordable education;
• research-based undergraduate scholarships to provide co-curricular opportunities; and
• direct support for faculty research to accelerate discovery and solutions.

New programs made possible in the College by Transforming Tomorrow include the Student Transfer Enrichment Program (STEP), which helps transfer students thrive through academic support, social engagement, and leadership development, as well as the Rising Tide program, which helps recruit and mentor early-career scientists. Also noteworthy is the enhanced Career Education Program, which connects students with alumni and career opportunities. 

A vision for the future

The College’s success contributes to the broader campaign, which has raised more than $1.6 billion toward its $2 billion goal. Fiscal year 2025 was the most successful fundraising year in Georgia Tech’s history, with nearly $300 million raised in new philanthropic support. Earlier this month, the Institute announced a historic $100 million bequest — the largest single gift in Tech’s history.

What’s next

As the campaign continues, the College of Sciences will remain focused on expanding student opportunities, accelerating scientific discovery, and supporting faculty excellence. The top priority for the Dean is creating opportunities for students to have access to a Georgia Tech education through need-based scholarships and graduate fellowships which provide a competitive advantage in recruiting the best and brightest students to our programs. 

“We are extremely grateful for the alumni, friends, students, faculty, staff, and corporations who have supported us so far,” says Warren. “Thanks to you, we’re heading into the final stretch of the campaign with wind in our sails. Now is the perfect moment to invest in the students, educators, and researchers driving tomorrow’s breakthroughs.” 

To learn more or make a gift to the College of Sciences, contact Dan Warren, director of Development for the College of Sciences, at dan.warren@cos.gatech.edu.

“Georgia Tech has emerged as a unique case in American higher education — an institution that delivers some of the best student outcomes in the nation while growing at a record pace in terms of enrollment, degrees granted, and research,” said Georgia Tech President Ángel Cabrera. “I am delighted to see rankings like these recognize Georgia Tech among the best public universities in the nation, and I invite families, students, employers, and corporate partners to reach out and learn more about what we’re doing here.”

Academic Distinctions

Georgia Tech also distinguished itself in areas that reflect the quality of the student experience and support for undergraduates. The Institute ranked No. 16 for Best Colleges for Veterans, maintaining its position from last year, and placed No. 3 nationally for internships and co-ops, underscoring Tech’s emphasis on hands-on learning opportunities. The senior capstone experience held steady at No. 12, highlighting the Institute’s commitment to preparing students for real-world problem-solving.

In addition, Georgia Tech ranked No. 21 in Best Undergraduate Teaching, rising 10 places from last year, and No. 3 in Most Innovative Universities, continuing a streak of top-five placements. 

Science and Math Excellence

Among  universities offering undergraduate, master’s, and doctoral programs, Georgia Tech ranks No. 32 nationally. U.S. News & World Report formally ranks only a handful of undergraduate programs in math and science. This year, the College of Sciences' undergraduate program in psychology entered the top 40 for the first time, moving up 30 places to No. 33. 

College of Sciences graduate programs are consistently ranked in the top 10% of accredited programs. The latest U.S. News & World Report Best Graduate School Rankings, published in April 2023, features all six College of Sciences schools among its best science schools for graduate studies. Several specialties also received high marks.

See ranking updates for other Georgia Tech programs here.

*Please note that this summary includes the latest rankings issued by U.S. News & World Report. Not all Georgia Tech Colleges, Schools, and subjects are ranked every year by this organization.

Purpose Built for AI Discovery

Nexus is Georgia Tech’s next-generation supercomputer, replacing the HIVE. Most operational high-performance computing systems utilized for research were designed before the explosion in Machine Learning and AI. This revolution has already shown successes for scientific research and data analysis in many domains, but the compute power, complex connectivity, and data storage needs for these systems have limited their access to the academic research community. The Nexus supercomputer design process retained a robust HPC system as a base while integrating artificial intelligence, machine learning and large-scale data science analysis from the ground up.

Expert Support for Faculty and Researchers 

The Institute for Data Engineering and Science (IDEaS) and the College of Computing house the Center for Artificial Intelligence in Science and Engineering (ARTISAN) group. This team has collective experience in working with national computational, cloud, commercial and institutional resources for computational activities, and decades of experience in scientific tools that aid in assisting both teaching and research faculty. Nexus is the next logical step, bringing together everything they’ve learned to build a national resource optimized for the future of AI-driven science.

Principal Research Scientist for the ARTISAN team, Suresh Marru, highlighted the need for this new resource, “AI is a core part of the Nexus vision. Today, researchers often spend more time setting up experiments, managing data, or figuring out how to run jobs on remote clusters than doing science. With Nexus, we’re flipping that script. By embedding AI into the platform, we help automate routine tasks, suggest optimal ways to run simulations, and even assist in generating input or analyzing results. This means researchers can move faster from question to insight. Instead of wrestling with infrastructure, they can focus on discovery.”

An Accessible AI Resource for GT & US Scientific Research

90% of Nexus capacity will be made available to the national research community through the NSF Advanced Computing Systems & Services (ACSS) program. Researchers from across the country, at universities, labs, and institutions of all sizes, will have access to this next-generation AI-ready supercomputer. For Georgia Tech research faculty and staff, the new system has multiple benefits:

• 10% of the time on the machine will be available for use by Georgia Tech researchers
• Nexus will allow GT researchers a chance to try out the latest hardware for AI computing
• Thanks to cyberinfrastructure tools from the ARTISAN group, Nexus will be easier to access than previous NSF supercomputers

Interim Executive Director of IDEaS and Regents' Professor David Sherrill notes, "Nexus brings Georgia Tech's leadership in research computing to a whole new level. It will be the first NSF Category I Supercomputer hosted on Georgia Tech's campus. The Nexus hardware and software will boost research in the foundations of AI, and applications of AI in science and engineering."

In our work as evolutionary biochemists and protein historians, these core questions form the foundation of our research programs. To study life’s history billions of years ago, we often use clues called molecular “fossils” – ancient structures shared by all living organisms.

Recently, we discovered that an important molecular fossil found in an ancient protein family may not be what it seems. The dilemma centers, in part, on a simple question: What does it mean if a simple molecular structure – the fossil – is found in every single organism on Earth? Do molecular fossils point to the seeds that gave rise to modern biological complexity, or are they simply the stubborn pieces that have resisted erosion over time? The answers have far-reaching implications for how scientists understand the origins of biology.

Follow the Phosphorus to Follow Life

Life is made of many different building blocks, one of the most important of which is the chemical element phosphorus. Phosphorus makes up part of your genetic material, powers complex metabolic reactions and acts as a molecular switch to control enzymes.

Phosphorus compounds – specifically a charged form called phosphate – have a number of unique chemical properties that other biological compounds cannot match. In the words of the pioneering organic chemist F.H. Westheimer, they are chemically able to “do almost everything.”

Their unique combination of stability, versatility and adaptability is why many researchers argue that following phosphorus is key to finding life. The presence of phosphorus both close to home – in the ocean or on one of Saturn’s moons – and in the farthest reaches of our galaxy is strong evidence for the potential for life beyond Earth.

Phosphate is part of many essential biological molecules, including the building blocks of DNA. Charles Molnar and Jane Gair, CC BY-SA

If phosphorus is so critical to life, how did early biology predating cells first use it?

Today, biological organisms are able to make use of phosphates through proteins – molecular machines that regulate all aspects of life. By binding to proteins, phosphates regulate metabolism and cellular communication, and they serve as a source of cellular energy.

Further, the process of phosphorylation, or adding a phosphate group to a protein, is ubiquitous in biology and allows proteins to perform functions their individual building blocks cannot. Without proteins, the existence of organisms such as bacteria and humans may not be possible.

Given how essential phosphorus is to life, scientists hypothesize that phosphate binding was among the first biological functions to emerge on Earth. In fact, current evidence suggests that the first phosphate-binding proteins are truly ancient – even older than the last universal common ancestor, the hypothetical mother cell to all life on Earth that existed around 4 billion years ago.

A Mysterious Phosphate-Binding Fossil

One family of phosphate-binding proteins, called P-loop NTPases, regulates everything from the communication between cells to the storage of energy and are found across the tree of life. Because P-loop NTPases are among the most ancient protein families, analyzing their properties can provide key insights into both the emergence of proteins and how primitive life used phosphates.

Although P-loop NTPases are diverse in structure, they share a common motif called a P-loop. This component binds to phosphate by wrapping a nest of amino acids – the building blocks that make up proteins – around the molecule. Every known organism has multiple families of P-loop NTPase, which makes the P-loop an excellent example of a molecular fossil that can provide clues about the evolution of life. Our crude analysis of the human genome estimates that humans have about 5,000 copies of P-loops.

When part of a larger protein structure, the P-loop folds like origami into a shape that is ideal for hugging a phosphate molecule. These nests are extremely similar to each other, even when the surrounding proteins are only distantly related in function. A landmark study in 2012 argued that even if the P-loop nest is extracted from a protein, it can still bind to phosphate. In other words, the ability of a P-loop to form a nest is determined by its interactions with phosphate, not its protein scaffold.

This study provided the first evidence that some forms of the P-loop sequence could have functioned billions of years ago, even before the emergence of large, complex proteins. If true, this implies that P-loop nests may have seeded the emergence and evolution of many of the phosphate-binding proteins seen today.

Interrogating the History of the P-loop

The pioneer of bioinformatics, Margaret Oakley Dayhoff, hypothesized in 1966 that the large collection of big proteins seen today arose from small peptides that were duplicated and fused over long periods of time. Although P-loops may have evolved in a different way, Dayhoff’s realization was the first to clarify how complex forms could have arisen from much simpler ones.

Inspired by Dayhoff’s hypothesis, we sought to interrogate the role that simple P-loops may have played in the evolution of the complex proteins key to life. Our findings challenge what’s currently known about these molecular fossils.

The Dayhoff hypothesis proposed that large, complex proteins arose from the duplication and merging of smaller, simpler peptides over time. Merski et al./Biomolecules, CC BY-SA

Using computer models, we compared a range of P-loops from the P-loop NTPase family to a control group made of the same amino acids but in a different order. While these control loops are also found in proteins, they do not form nests.

Although the P-loops and the control loops are very different in their nest-forming ability, we found that they both are able to form transient nests when embedded in proteins. This meant that, contrary to popular belief, the amino acid sequence of P-loops aren’t special in their ability to form nests – as would be expected if they alone were the seeds for many modern proteins.

A Fossil Eroded Over Time

Our work strongly suggests that while the P-loop is a molecular fossil, the true nature of its form billions of years ago may have been eroded by the sands of time.

For example, when we repeated our simulations in a different solvent – specifically methanol – we found that P-loops situated in their parent proteins were able to regain some of their ability to form nests. This doesn’t mean that being in methanol drove the first proteins with P-loops to form the nests critical for life. But it does emphasize the importance of considering the surrounding environment when studying peptides and proteins.

Just as archaeologists know to be careful in how they interpret physical fossils, historians of protein evolution could take similar care in their interpretation of molecular fossils. Our results complicate the current understanding of early protein evolution and, consequently, some aspects of the origins of life.

In resetting the field’s broader understanding of how these crucial proteins emerged, scientists are poised to start rewriting our own evolutionary history on this planet.

This article is republished from The Conversation under a Creative Commons license. Read the original article.

IMS focuses on transformational technological and societal systems that arise where innovative materials, devices, and processes converge.

“Interdisciplinary research often struggles to find a home,” said Michael Filler, IMS deputy director. “IMS aims to fill that gap—through programs like the CPI, we provide a place where unconventional collaborations from across Georgia Tech and beyond can take root, grow, and ultimately redefine what’s possible.

The funded initiatives come from four colleges and 11 schools across the Institute, and from GTRI. These research projects were selected based on their innovative approaches, potential impact, and alignment with IMS’ mission to push the boundaries of science and technology. They will receive funding, access to state-of-the-art facilities, and other support from IMS to bring their projects to life.

IMS supports interdisciplinary research both in nationally recognized areas of need and those just emerging. It scaffolds research from the ground up, from seed funding for new initiatives to infrastructure support for research programs and embedded support for research centers. The four newly announced initiatives are funded at the lowest level of IMS’ three-tiered model.

The two new research programs were previous IMS research initiatives that have been elevated to the program level. The successful elevation to research program highlights the funding pipeline and its design to support novel interdisciplinary research. As initiatives, these researchers were given seed funding and support for workshops, visioning and team nucleation, they demonstrated dedication to their research and team building. As IMS research programs, these projects will have the opportunity to expand their operations including with support for team expansions, proposals, and some staff support. 

“The IMS funding pipeline is about giving researchers a ladder where none exists—support to take the first step with a new idea, and the structure to keep climbing as their work matures,” said Filler. “By providing that scaffold, we enable bold, interdisciplinary teams to turn early sparks of discovery into thriving research programs with real-world impact.”

The new research initiatives and programs:

Research Initiatives

Multifunctional Materials for Efficient Buildings | Akanksha Menon, George W. Woodruff School of Mechanical Engineering

Adaptive Biomacromolecular and Cellular Networks | Anant Paravastu, School of Chemical and Biomolecular Engineering; Vinayak Agarwal, School of Chemistry and Biochemistry; Andrew McShan, School of Chemistry and Biochemistry; and Itamar Kolvin, School of Physics

Precision Agriculture in Controlled Environments | Antonio Facchetti, School of Materials Science and Engineering; Yongsheng Cheng, School of Civil and Environmental Engineering; Anju Toor, School of Materials Science and Engineering

Electrochemical Manufacturing of Materials and Resource Recovery | Hailong Chen, George W. Woodruff School of Mechanical Engineering

Research Programs

Autonomous Research for Materials | Mark Losego, School of Materials Science and Engineering; Shreyas Kousik, George W. Woodruff School of Mechanical Engineering; Animesh Garg, School of Interactive Computing

Magnetometry and Spectrum-Based Quantum Sensing Platforms| Zhigang Jiang, School of Physics; Martin Mourigal, School of Physics; Yan Wang, George W. Woodruff School of Mechanical Engineering

Learn more about IMS’s research focuses and see a full list of its centers, programs, and initiatives.

This interdisciplinary program is designed for humanities students interested in careers in health and science, media, technical communication, or public relations, as well as STEM majors seeking to develop their human-centered communication skills.

Students must take LMC 3310 – The Rhetoric of Scientific Inquiry and PUBP 4410 – Science, Technology, and Public Policy and also choose three electives from a list of courses that includes LMC 3412 – Communicating Science and Technology to the Public, LMC 3318 – Biomedicine and Culture, and LMC 4406 – Contemporary Issues in Professional Communication.

A unique feature of this minor is the optional study-abroad experience in Dublin, Ireland, on storytelling and AI in journalism, offered in partnership with CNN.

“This is an exciting opportunity for Georgia Tech students to learn how policy shapes and is shaped by how we talk about science and to learn how scientific advances are communicated by professionals to different public audiences,” said LMC Chair Kelly Ritter.

The Minor in Science Communication and Policy is one of three new minors offered by the Ivan Allen College this fall.

“We are incredibly proud to see four outstanding alumni from the College of Sciences recognized in this year’s 40 Under 40,” says Leslie Roberts, director of Alumni Relations for the College of Sciences. “Their achievements are a testament to the power of scientific curiosity and innovation to shape a better future.”

Meet the inspirational honorees from the College of Sciences:

Brandi Brown, BIO 2013

Founder/CEO | Gulf Spore 

Brandi Brown is making waves in the mushroom industry. Upon graduating from Georgia Tech, she commissioned as an officer in the United States Air Force. After serving her country, she earned a Ph.D. in bioengineering, focusing on the development of bioplastics from microbes. Recognizing the beauty and potential of fungi, she founded Gulf Spore, a mushroom biotech company dedicated to solving many of humanity’s greatest challenges, such as food waste. Gulf Spore was awarded a Small Business Innovation Research grant by the National Science Foundation. 

Favorite Tech Memory: One of my favorite memories was getting to perform Honor Guard at the GT football game as a rifle bearer!

Victoria Fritz, BIO 2017

Founder/CEO | BabyBumps 

Dr. Victoria Fritz is a physician turned entrepreneur. After graduating from Georgia Tech, Fritz went to medical school at the University of North Carolina–Chapel Hill and matched into cardiothoracic surgery (heart and lung surgery) for residency. After a major medical diagnosis forced her to leave her career in heart surgery, she launched BabyBumps, a company focused on the fertility space with a mission to elevate the value of women in surrogacy.  

Favorite Tech Memory: I met my husband when we were students at Tech! He is now my most important business partner.

Mitchell Hanson, NEURO 2020 

MD/MPH Student | Medical College of Georgia 

Mitchell Hanson is a Doctor of Medicine and Master of Public Health candidate at the Medical College of Georgia with interests in public health, dermatology, and fitness. He has presented at national and international conferences, published in high-impact journals including the Journal of the American Academy of Dermatology and the Alzheimer’s Association, and appeared on TEDx and AMA national platforms. He has managed nearly $50,000 in grant funding for community health initiatives and completed his MPH internship in Vietnam researching vascular anomalies and laser technologies. As the current president of his institution’s Gold Humanism Honor Society chapter, Hanson aims to reshape medicine through medical media, artistic expression, and a reimagined identity of physicianship. He was inducted into the AMA Leadership Development Institute 2025-26 Health Administration and Management Cohort. 

Favorite Tech Memory: The Biomolecular Engineering, Science, and Technology (BEST) Study Abroad Program in Lyon. I made lifelong friends there, including one whose wedding I just officiated for!

Anthony Rojas, CHEM 2014 

Senior Academic Professional | Georgia Tech 

Anthony J. Rojas is a senior academic professional in chemistry at Georgia Tech. He earned his Ph.D. from MIT and his bachelor’s from Georgia Tech, both in chemistry. His research spans peptide therapeutics, transition metal catalysis, and inclusive chemistry education, with over a dozen peer-reviewed publications. A passionate educator, he has received multiple teaching awards and led funded projects from NIH, NSF, and ACS. Rojas is committed to mentorship and outreach. He integrates light-board technology and active learning to enhance student engagement and success in the chemistry classroom. 

Favorite Tech Memory: Meeting my people, including my future wife!

Learn more about the 2025 class on the Georgia Tech Alumni Association’s website or by exploring the interactive honoree dashboard.

The Center for Teaching and Learning (CTL) and the Office of Academic Effectiveness (OAE) have announced the Spring 2025 Course Instructor Opinion Survey (CIOS) Honor Roll. 

Georgia Tech faculty members who made the Spring 2025 Honor Roll have been celebrated by their students for outstanding teaching and educational impact. Students overwhelmingly praised these educators for their excellent teaching methods and dedication to student success. Each Honor Roll recipient receives a certificate from the Center for Teaching and Learning recognizing their accomplishment as well as an invitation to the next Celebrating Teaching Day held in March 2026.

The College of Sciences congratulates the following faculty members who have been named to the Spring 2025 CIOS Honor Roll:

College of Sciences – Small Classes

• Benjamin McKenna, recognized for MATH 3235: Probability Theory
• Colin Harrison, recognized for BIOS 4803: Special Topics: Sexual Differentiation Humans
• Katharine McCann, recognized for NEUR 4803: Special Topics: Neuroscience of Addiction
• Liana Boop, recognized for EAS 1600: Intro-Environmental Sci
• Mark Hay, recognized for BIOS 4417: Marine Ecology
• Mark Himmelstein, recognized for PSYC 2020: Psychological Statistics
• Sven Simon, recognized for PHYS 4803: Special Topics: Space Plasma Physics
• Will Gutekunst, recognized for CHEM 6750: Prep&Reactions-Polymers

College of Sciences – Large Classes

• Adam Decker, recognized for BIOS 3753: Human Anatomy
• Anjuli Datta, recognized for BIOS 4570: Immunology
• Anthony Rojas, recognized for CHEM 3111: Inorganic Chemistry
• Christopher Haines, recognized for CHEM 2312: Organic Chemistry II
• Emily Weigel, recognized for BIOS 4401: Exper Dgn &Statis Methods
• Hannah Smith, recognized for BIOS 3380: Microbiology
• Mioy Huynh, recognized for CHEM 1310: Prin of Gen Chem for Engr
• Pamela Pollet, recognized for CHEM 2311: Organic Chemistry I
• Robert Richards, recognized for BIOS 4401: Exper Dgn &Statis Methods
• William Stern, recognized for PSYC 2210: Social Psychology

The full Spring 2025 CIOS Honor Roll can be found on CTL’s website.

“Malaria kills over 500,000 annually with the mortality rate substantially higher in Africa,” says Frooman. “Our research explores how specific peptides bind to proteins that trigger immune responses.”

Frooman originally hoped the research would help her learn how to think like a scientist and gain basic lab knowledge.

She gained those skills and more, quickly becoming recognized as an exceptional researcher.

“Marielle is one of the most passionate and talented undergraduate researchers I have ever worked with,” says Andrew McShan, McShan Lab principal investigator and associate professor in the School of Chemistry and Biochemistry. “She is also a caring mentor and motivated future leader who wants to change the world. Her malaria research has the potential to provide real therapeutic outcomes, including better designs for vaccines and immunotherapy.” 

From curiosity to contribution

Frooman’s journey into undergraduate research began with persistence. After a year and a half of searching for lab opportunities, she attended a School of Chemistry and Biochemistry research showcase. She approached several graduate students and professors with no success, until she met McShan.

“Our first meeting was so relaxed and friendly that I didn’t even realize Professor McShan was the principal investigator,” admits Frooman. “That’s how it all started.”

Once she officially joined the lab, Frooman contributed to every stage of the research, including designing experiments, performing computational and wet lab work, analyzing data, and writing and presenting the paper.

Lessons in resilience

The team faced several challenges.

“The research was delayed by failure after failure,” says Frooman. “But each setback taught us something valuable.”

The team’s biggest challenge involved trying to grow crystals of the peptide/HLA (protein) complexes to determine how they fit together. They spent two years attempting various methods, but nothing worked.

Guided by McShan, Frooman and the team then came up with the idea of using computational modeling to enable a deeper understanding of how the peptides and proteins interact at both biophysical and structural levels.

“Utilizing the computational modeling enabled us to see the best bindings and turned into a game-changing insight for our research, potentially leading to the design of more effective malaria treatments and vaccines,” explains Frooman.

She is quick to credit Georgia Tech and McShan for providing her with such a valuable learning experience.

“At many universities, undergraduates rarely do meaningful research, but at Tech, it’s a priority,” explains Frooman. “I’m extremely grateful for the opportunity to grow in such a supportive environment, and to learn from mentors like Professor McShan who lead by example and make time for every student.”

Her advice to other undergraduates entering research?

“Embrace your failures. They make the successes even more rewarding,” shares Frooman.

Outside the lab

On campus, Frooman is president of the Student Affiliates of the American Chemical Society and Cleanup Crew at GT, a member of Alpha Phi International Fraternity, and a campus tour guide who serves on their executive board. 

She especially loves being a tour guide as it allows her to share her love of Georgia Tech and its people:

“Everyone is unapologetically themselves and fully invested in their major or interests. As someone who loves chemistry, I enjoy being surrounded by people who are just as dedicated to their passions.”

Frooman is a recipient of the Chance Family Scholarship, presented to two School of Chemistry and Biochemistry upperclassmen, recognizing their academic excellence, research contributions, and potential for career success in the field.

Recently, she shifted her research focus to organic synthetic chemistry and now works in the Gutekunst Lab. Her career goals include earning a Ph.D. in Chemistry with an emphasis on natural product synthesis, the lab-based creation of complex chemical compounds found in nature.

“I’ve seen what university labs can do,” says Frooman. “I hope to one day lead my own lab, advancing impactful research and mentoring the next generation of scientists.”

Read the article here »

“When I was 14, I dreamed about being in space one day,” recalls Chen, 22, a native of Hong Kong and a Ph.D. student in aerospace engineering. “I think the industry has been making space more accessible to everyone. Commercialization is a big part of enabling this.”

Gantt, an engineer and former U.S. Army veteran graduating with an MBA from the Scheller College of Business this spring, remembered seeing the space shuttle retire and companies begin privatizing space as he entered young adulthood. 

“I’ve always been interested in space, and a lot of it comes from the challenge of going to space,” he observes. “Seeing how hard it is to get to space and seeing it become achievable — that to me was the most attractive thing about it.”

For Gantt, the feeling always brings to mind John F. Kennedy’s famous line that spelled out America’s space ambitions: “We choose to go to the moon in this decade and do the other things, not because they are easy, but because they are hard.”

Recognizing Georgia Tech’s aerospace strengths, Gantt didn’t waste time building bridges within Scheller and in other parts of Georgia Tech. He founded the Scheller MBA Space Club, a first at the College, to track the industry as it grows and develops. 

“I came from a military background, so I had my eye on the defense industry going into the MBA program. Georgia Tech, being the No. 2 aerospace engineering undergraduate school in the nation, I knew they already had strong industry connections. Making connections was a big goal coming into this program.”

Assessing Early-Stage Space Tech 

He took part in the Entrepreneurship Assistants Program (EAP), which pairs a Scheller MBA student with a faculty or student inventor to evaluate early-stage technology for potential commercialization. He evaluated two space-related technologies, one with Chen’s support. 

“The EAs conduct technology commercialization assessments and develop a business model canvas. By applying an entrepreneurial strategy compass, they predict potential go-to-market strategies for new technology,” says Paul Joseph, principal in the Office of Commercialization’s Quadrant-i unit, who created the EAP.

 (See sidebar to read more about the EAP and the specific technologies assessed.)

Tapping Into a Nearly $2T Industry

According to McKinsey & Co., the space technology market, fueled by advancements in satellite technology, commercial space travel, and 5G networks, is projected to reach $1.8 trillion by 2035.

“We're seeing an industry shifting from a multibillion-dollar market cap to a multitrillion-dollar market cap in less than a decade. If you look at this from a business perspective, this is a massive addressable market for entrepreneurs," says Gantt.

From its Center for Space Technology and Research to the new Center for Space Policy and International Relations and labs like the Space Systems Design Lab, which focuses on areas such as CubeSat propulsion, lunar research, and hypersonic flight, Georgia Tech excels in space research across disciplines. In July, Georgia Tech will launch the Space Research Institute (SRI), one of its newest Interdisciplinary Research Institutes (IRI), to foster additional collaboration in this growing field.

“At Georgia Tech, there are competencies across every single College that will help to augment our understanding of space,” says Alex Oettl, professor of strategy and innovation in Scheller College, whose interest in the new space economy spans the last 20 years. “When you look at the technologies coming from Georgia Tech, they can impact this future trillion-dollar industry.”

 An economist by training, Oettl led Georgia Tech’s involvement in the Creative Destruction Lab-Atlanta, a multi-university program that helped commercialize early-stage scientific technologies.

Leveraging Affordable Launch

The emergence of affordable launch, spurred by SpaceX’s introduction of the Falcon 9 rocket using reusable rocket technology, has made space much more accessible, from biomedical companies to academic institutions.

“Because there has been a drop in the cost of accessing space, it allows experimentation to flourish,” says Oettl. 

He recalls Mark Costello, former chair of the Daniel Guggenheim School of Aerospace Engineering, explaining how he could launch a CubeSat into Low Earth Orbit out of his research budget, whereas before it would have been cost-prohibitive.

Today, Georgia Tech students and researchers are poised to capitalize on the new space economy stack — from new launch capabilities to new development in propellants and in-space operations and maintenance to more powerful sensors on Earth-observation satellites.

“I’ve seen firsthand the traction occurring on the commercial side. There are a lot of social scientists waking up to the opportunity that exists and thinking about business dynamics that will emerge as a result of this great opportunity,” he says.

Georgia Tech, an interdisciplinary, tech-focused university, brings significant capabilities across its Colleges to drive new and emerging technologies that have implications for space. 

“Space hits on all the strengths that exist at the various Colleges,” Oettl explains. “Faculty at Georgia Tech are pushing the boundary and showing our students innovations that will emerge in the space economy that are not immediately obvious — such as in adjacent industries.”

Oettl calls these first-order and spillover impacts of new technology. By first-order impacts, he means businesses can take advantage of these opportunities and create new products on top of the original innovation. By spillovers, he cites as an example an Earth-observation satellite enabling other industries to take advantage of data from the ground. For instance, insurance companies are one of the largest users of space technology by way of satellite imagery.

Bringing Capabilities Together Through New Space IRI

The SRI will bring together the best in engineering, computer science, policy, and business research across Georgia Tech. Along the way, it could help engineers and computer scientists think with a more business-minded approach to pitch their innovations to the commercial space sector. 

“You don’t see a lot of engineers having that inherent ability,” notes Gantt. “The Space IRI can shine by fostering collaboration between business students and engineers, enabling them to develop innovative go-to-market strategies and clearly define the unique value propositions these technologies offer to end users. You can bring these people together and create some forward momentum in the space industry.”

This story by Janette Neuwahl Tannen is shared jointly with the University of Miami newsroom. 

Today, most of us carry a fairly powerful computer in our hand — a smartphone.

But computers weren’t always so portable. Since the 1980s, they have become smaller, lighter, and better equipped to store and process vast troves of data.

Yet the silicon chips that power computers can only get so small.

“Over the past 50 years, the number of transistors we can put on a chip has doubled every two years,” says Kun Wang, assistant professor of physics at the University of Miami College of Arts and Sciences. “But we are rapidly reaching the physical limits for silicon-based electronics, and it’s more challenging to miniaturize electronic components using the technologies we have been using for half a century.”

It’s a problem that Wang and many in his field of molecular electronics are hoping to solve. Specifically, they are looking for a way to conduct electricity without using silicon or metal, which are used to create computer chips today. Using tiny molecular materials for functional components, like transistors, sensors, and interconnects in electronic chips offers several advantages, especially as traditional silicon-based technologies approach their physical and performance limits.

But finding the ideal chemical makeup for this molecule has stumped scientists. Recently, Wang, along with his graduate students, Mehrdad Shiri and Shaocheng Shen, and collaborators Jason Azoulay, associate professor at Georgia Institute of Technology and Georgia Research Alliance Vasser-Woolley Distinguished Investigator; and Ignacio Franco, professor at the University of Rochester, uncovered a promising solution.

This week, the team shared what they believe is the world’s most electrically conductive organic molecule. Their discovery, published in the Journal of the American Chemical Society, opens up new possibilities for constructing smaller, more powerful computing devices at the molecular scale. Even better, the molecule is composed of chemical elements found in nature — mostly carbon, sulfur, and nitrogen.

“So far, there is no molecular material that allows electrons to go across it without significant loss of conductivity,” Wang says. “This work is the first demonstration that organic molecules can allow electrons to migrate across it without any energy loss over several tens of nanometers.”

The testing and validation of their unique new molecule took more than two years.

However, the work of this team reveals that their molecules are stable under everyday ambient conditions and offer the highest possible electrical conductance at unparalleled lengths. Therefore, it could pave the way for classical computing devices to become smaller, more energy-efficient, as well as cost-efficient, Wang adds.

Currently, the ability of a molecule to conduct electrons decreases exponentially as the molecular size increases. These newly developed molecular “wires” are needed highways for information to be transferred, processed, and stored in future computing, Wang says.

“What’s unique in our molecular system is that electrons travel across the molecule like a bullet without energy loss, so it is theoretically the most efficient way of electron transport in any material system,” Wang notes. “Not only can it downsize future electronic devices, but its structure could also enable functions that were not even possible with silicon-based materials.”

Wang means that the molecule’s abilities might create new opportunities to revolutionize molecule-based quantum information science.

“The ultra-high electrical conductance observed in our molecules is a result of an intriguing interaction of electron spins at the two ends of the molecule,” he adds. “In the future, one could use this molecular system as a qubit, which is a fundamental unit for quantum computing.”

The team was able to notice these abilities by studying their new molecule under a scanning tunneling microscope (STM). Using a technique called STM break-junction, the team was able to capture a single molecule and measure its conductance.

Shiri, the graduate student, adds: “In terms of application, this molecule is a big leap toward real-world applications. Since it is chemically robust and air-stable, it could even be integrated with existing nanoelectronic components in a chip and work as an electronic wire or interconnects between chips.”

Beyond that, the materials needed to compose the molecule are inexpensive, and it can be created in a lab.

“This molecular system functions in a way that is not possible with current, conventional materials,” Wang says. “These are new properties that would not add to the cost but could make (computing devices) more powerful and energy efficient.” 

DOI: https://doi.org/10.1021/jacs.4c18150

Funding: U.S. Department of Energy, Office of Science, Basic Energy
Sciences; National Science Foundation (NSF); Air Force Office of Scientific Research (AFOSR) under support provided by the Organic Materials
Chemistry Program; Georgia Tech Research Institute (GTRI) Graduate
Student Researcher Fellowship Program (GSFP). Computational resources were provided by the Center for Integrated Research Computing (CIRC) at the
University of Rochester.

Along with Jason Azoulay, Georgia Tech co-authors also include Paramasivam Mahalingam, Tyler Bills, Alexander J. Bushnell, and Tanya A. Balandin.

“Academic CVs rarely, if ever, carry the human stories underlying professional accomplishments,” Kamerlin says. “I have chosen to be open about my battles with infertility and my experiences as a rare disease patient to help others feel less alone. Because of that decision, receiving this award, which recognizes those experiences and their role in shaping my career beyond my visible professional accomplishments, really means a lot to me.”

She hopes that her story and the visibility of this award will encourage and inspire other scientists who are navigating their career paths and facing their own challenges. 

Kamerlin, who joined the Institute in 2022, has also served as a Lise Meitner Guest Professor of Molecular Design at Lund University in Sweden since 2025. She obtained a Ph.D. in Theoretical Organic Chemistry from the University of Birmingham and completed her postdoctoral research at the University of Vienna and University of Southern California. 

Her research lab focuses on understanding the role of conformational dynamics — changes in the  three-dimensional shape of a protein — in protein evolution, and how these dynamics can be exploited to engineer novel proteins with tailored biocatalytic properties. 

Kamerlin has been extensively involved in high-level science policy, particularly relating to open science and researcher careers. She served as chair of the Young Academy of Europe and as a member of the executive council of the Protein Society. Kamerlin has also been deeply engaged in efforts to support women in science, broaden European participation in research, and promote the careers of young scientists.

McShan, an assistant professor in the School of Chemistry and Biochemistry, has been awarded a $1.4 million CAREER grant from the National Science Foundation (NSF) to support this research.

“Protein-lipid assemblies carry out all sorts of biological functions, and harnessing their interactions could lead to powerful tools and treatments — but historically, they’ve been difficult to study,” McShan says. “Building resources for researchers and making this information accessible are critical steps in developing this field. This CAREER grant will enable me to expand the current knowledge base, while also allowing me to develop a class that will train the next generation of researchers, which is hugely important to me.”

The NSF Faculty Early Career Development Program is a five-year grant designed to help promising researchers establish a foundation for a lifetime of leadership in their field. Known as CAREER awards, the grants are NSF’s most prestigious funding for early-career faculty.

Expanding access

Crucial for nearly all biological processes, lipid-protein interactions play a key role in everything from immune responses to energy storage — but what drives their interactions has historically been difficult to map and understand.

McShan will use the CAREER grant to expand that knowledge base, experimenting in the lab to characterize protein-lipid interactions, and developing computational tools that can predict those interactions. The work will include an in-depth study of how lipids interact with different families of proteins that are important for immune system function.

“Right now, understanding protein-lipid assemblies is expensive in both time and lab materials,” McShan says. “My goal is to create computer models that can predict how these biomolecular interactions occur, what they look like, and how they contribute to cellular functions.”

The new model would allow researchers to quickly and inexpensively ‘experiment’ with molecules on a computer, vastly expanding the amount of research that could be conducted. 

The project builds on McShan’s recent publication in the Nature-family journal Communications Chemistry, which showcased BioDolphin — a first-of-its-kind, comprehensive, and annotated database of protein-lipid interactions that are all integrated into a user-friendly web server and freely accessible to all. 

It’s also adjacent to research funded by a Curci Grant from the Shurl and Kay Curci Foundation, which McShan was previously awarded for research on cutting-edge cancer treatments that involved identifying new cancer lipid signatures in tumor cells, and characterizing known cancer lipid antigens.

Pioneering the future of research

Additionally, the CAREER grant will support McShan’s initiatives to train the next generation of researchers through a new class centered around hands-on laboratory research and peer mentorship. Students will have the opportunity to pick a protein-lipid assembly, study it using computational and experimental biophysical methods, develop testable hypotheses, and — if successful — publish their results in peer reviewed journals.

The class will also pair undergraduate and graduate students into research teams. “I’m excited to see how a peer mentoring approach will add depth to the class,” McShan shares, explaining that graduate students will gain valuable mentoring experience in a collaborative research environment. “This is very different from typical mentoring experiences many graduate students have, which tend to be more along the lines of a TA experience rather than collaborating on hands-on research.”

“This type of class, to my knowledge, hasn’t been offered before, and there’s a lot of research that I’m doing to lay the groundwork for it,” McShan adds. “Hopefully, it can not only introduce students to lipid-based research — something typically lacking in many biochemistry curricula — but also to the type of collaborative mentorship we want to foster in research.”