{"93631":{"#nid":"93631","#data":{"type":"event","title":"(08-0304) Prof. Tim Warren, Georgetown University","body":[{"value":"\u003Cp\u003EProf. Tim Warren, Georgetown University\n\u003C\/p\u003E\n\u003Cp\u003EDiscrete Late Metal Nitrenes in Catalytic C-H Amination\n\u003C\/p\u003E\n\u003Cp\u003ECatalytic C-H amination offers the opportunity to directly convert C-H bonds into amine functionalities without the need for prior chemical modification of these normally unreactive C-H bonds.  Electrophilic, late transition metal-nitrene complexes [M]=NR are believed to be the active intermediates in this challenging transformation, providing greater chemoselectivity than free nitrenes themselves. Using well-defined \u0026#61538;-diketiminato complexes of Co, Ni, and Cu, we demonstrate the synthesis of discrete metal-nitrene complexes which enables a detailed examination of their electronic structure as well as reactivity towards a variety of substrates.  These fundamental inorganic synthetic studies allow for the rational development of a catalytic system for the efficient amination of a wide variety of sp3-hybridized C-H bonds with organoazides.\n\u003C\/p\u003E\n\u003Cp\u003ELeading References:\n\u003C\/p\u003E\n\u003Cp\u003E(1) \u0022Transient Terminal Cu-Nitrene Intermediates from Discrete Dicopper Nitrenes\u0022 Badiei, Y. M.; Krishnaswamy, A.; Melzer, M.; Warren, T. H.  J. Am. Chem. Soc. 2006, 128, 15056-15057.\n\u003C\/p\u003E\n\u003Cp\u003E(2) \u0022A Terminal Ni(III)-Imide with Diverse Reactvity Pathways\u0022 Kogut, E.; Wiencko, H. L.; Zhang, L.; Cordeau, D. C.; Warren, T. H.* J. Am. Chem. Soc. 2005, 127, 11248-11249.\n\u003C\/p\u003E\n\u003Cp\u003E(3) \u0022[Me2NN]Co(\u0026#61544;6-toluene): O=O, O=N, and N=N Bond Cleavage Provides \u0026#61538;-Diketiminato \u0026#61549;-Oxo and Imido Complexes\u0022 Dai, X.; Kapoor, P.; Warren, T. H.   J. Am. Chem. Soc. 2004, 126, 4798-4799.\n\u003C\/p\u003E\n\u003Cp\u003EFor more information contact Dr. Jean-Luc Bredas (404-385-4986).\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Prof. Tim Warren, Georgetown University\n\nDiscrete Late Metal Nitrenes in Catalytic C-H Amination","format":"limited_html"}],"field_summary_sentence":[{"value":"Prof. Tim Warren, Georgetown University"}],"uid":"27275","created_gmt":"2007-10-18 00:00:00","changed_gmt":"2016-10-08 01:57:24","author":"Shirley Tomes","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2008-03-04T14:00:00-05:00","event_time_end":"2008-03-04T15:00:00-05:00","event_time_end_last":"2008-03-04T15:00:00-05:00","gmt_time_start":"2008-03-04 19:00:00","gmt_time_end":"2008-03-04 20:00:00","gmt_time_end_last":"2008-03-04 20:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/www8.georgetown.edu\/departments\/chemistry\/people\/warren.html","title":"Prof. Tim Warren, Georgetown University"}],"groups":[{"id":"85951","name":"School of Chemistry and Biochemistry"}],"categories":[],"keywords":[{"id":"89","name":"chemistry"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EShirley Tomes\u003C\/strong\u003E\u003Cbr \/\u003EChemistry \u0026amp; Biochemistry\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=st81\u0022\u003EContact Shirley Tomes\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-0591\u003C\/strong\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}