{"89811":{"#nid":"89811","#data":{"type":"event","title":"(11-1020) Prof. Tae-Hee Lee, Pennsylvania State University","body":[{"value":"\u003Cp\u003EProf. Tae-Hee Lee, Pennsylvania State University\n\u003C\/p\u003E\n\u003Cp\u003ESingle molecule studies on biological macromolecular assemblies\n\u003C\/p\u003E\n\u003Cp\u003ESchool Colloquia\n\u003C\/p\u003E\n\u003Cp\u003EBiological processes involving macromolecules and macromolecular assemblies often entail complex structural and positional dynamics of the molecules as important functional elements. These dynamics on the microsecond or longer time scale can be efficiently monitored with single molecule methods. Based on single molecule fluorescence and force measurements, we study tRNA selection by the ribosome, DNA clamp loading, and changes in nucleosome structure and dynamics induced upon DNA methylation and histone acetylation. I will present our findings in the three systems which demonstrate the stochastic nature of slow biological processes engaging macromolecular assemblies.\n\u003C\/p\u003E\n\u003Cp\u003EFor more information contact \u003Ca href=\u0022mailto:robert.dickson@chemistry.gatech.edu\u0022\u003EProf. Rob Dickson\u003C\/a\u003E (404-894-4007).\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"Prof. Tae-Hee Lee, Pennsylvania State University\n\nSingle molecule studies on biological macromolecular assemblies\n\nSchool Colloquia","format":"limited_html"}],"field_summary_sentence":[{"value":"Prof. Tae-Hee Lee, Pennsylvania State University"}],"uid":"27275","created_gmt":"2011-01-24 01:00:00","changed_gmt":"2016-10-08 01:50:45","author":"Shirley Tomes","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-10-20T17:00:00-04:00","event_time_end":"2011-10-20T18:00:00-04:00","event_time_end_last":"2011-10-20T18:00:00-04:00","gmt_time_start":"2011-10-20 21:00:00","gmt_time_end":"2011-10-20 22:00:00","gmt_time_end_last":"2011-10-20 22:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/www.chem.psu.edu\/directory\/txl18","title":"Prof. Tae-Hee Lee, Pennsylvania State University"}],"groups":[{"id":"85951","name":"School of Chemistry and Biochemistry"}],"categories":[],"keywords":[{"id":"6886","name":"women in chemistry"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cstrong\u003EShirley Tomes\u003C\/strong\u003E\u003Cbr \/\u003EChemistry \u0026amp; Biochemistry\u003Cbr \/\u003E\u003Ca href=\u0022http:\/\/www.gatech.edu\/contact\/index.html?id=st81\u0022\u003EContact Shirley Tomes\u003C\/a\u003E\u003Cbr \/\u003E\u003Cstrong\u003E404-894-0591\u003C\/strong\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}