{"71651":{"#nid":"71651","#data":{"type":"event","title":"Quantitative Redox Biology Working Group Discussion","body":[{"value":"\u003Cp\u003ERedox\nprocesses are at the foundation of nearly all aspects of biology.\u0026nbsp; In addition to free radicals, related\noxidants, and antioxidants, thiol\/disulfide redox regulation is central to the\nbasic functioning of cells and tissues.\u0026nbsp; All\nthese set the cellular redox environment and therefore are key to regulation of\nbiochemical pathways and networks, influencing organism health.\u0026nbsp; To understand better how cellular redox\nprocesses connect to the metabolome, proteome, lipidome, and genome we need\nabsolute, quantitative information on all redox active compounds as well as\nthermodynamic and kinetic information on their reactions, \u003Cem\u003Ei.e.\u003C\/em\u003E knowledge of the complete redoxome. Quantitative information\nis essential to establish the dynamic mathematical models needed to reveal the\ntemporal evolution of biochemical pathways and networks.\u0026nbsp; This new field of \u003Cem\u003EQuantitative Redox\nBiology\u003C\/em\u003E will allow researchers to identify new targets for intervention to\nadvance our efforts to achieve optimal human health. \u003C\/p\u003E\n\n\u003Cp\u003EThe goal of this\nworking group meeting is to initiate discussion on how we can help each other\nand the community as a whole advance research in \u003Cem\u003EQuantitative Redox Biology\u003C\/em\u003E.\u0026nbsp; \u003C\/p\u003E\n\n\u003Cp\u003EPlease note that this event is not sanctioned by SFRBM,\nalthough the society has kindly provided meeting space for us. \u0026nbsp;We will be convening primarily during the\nbreak between the SFRBM pre-meeting workshop and the President\u2019s Welcome. The\nformat of this working group meeting will be informal with very short\npresentations followed by discussion on the following topic areas:\u0026nbsp; \u003C\/p\u003E\n\n\u003Cul\u003E\u003Cli\u003EWhat is \u003Cem\u003EQuantitative Redox Biology\u003C\/em\u003E (QRB)?\u0026nbsp; \u003C\/li\u003E\u003Cli\u003EWhat types of data are needed for QRB?\u0026nbsp; \u003C\/li\u003E\u003Cli\u003EHow do we as a\ncommunity organize curation of data (\u003Cem\u003Ei.e\u003C\/em\u003E.\n\u0027redoxome\u0027 database)? \u0026nbsp;\u003C\/li\u003E\u003Cli\u003EShould there be\nstandardization of data reporting?\u0026nbsp; \u003C\/li\u003E\u003Cli\u003EWhat modeling tools are\nneeded to advance the field?\u0026nbsp; \u003C\/li\u003E\u003Cli\u003EHow can this group\nadvance kinetic analyses of one-electron and two-electron processes? \u2013 \u003Cem\u003Ee.g\u003C\/em\u003E. from superoxide\/metal reactions\nand\/or H\u003Csub\u003E2\u003C\/sub\u003EO\u003Csub\u003E2\u003C\/sub\u003E\/protein-cys\nmodifications to gene expression and metabolism.\u0026nbsp; \u003C\/li\u003E\u003Cli\u003EHow can we\ncollectively improve NIH funding opportunities in QRB?\u0026nbsp;.\u003C\/li\u003E\u003C\/ul\u003E\u003Cp\u003EComplimentary registration required, visit website below.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003E\u003Cstrong\u003E\u003C\/strong\u003EThe goal of this working group meeting\nis to initiate discussion on how we can help each other and the community as a\nwhole advance research in \u003Cem\u003EQuantitative Redox Biology\u003C\/em\u003E.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"The goal of this working group meeting is to initiate discussion on how we can help each other and the community as a whole advance research in Quantitative Redox Biology."}],"uid":"27349","created_gmt":"2011-10-20 11:23:00","changed_gmt":"2016-10-08 01:56:24","author":"Floyd Wood","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-11-16T14:30:00-05:00","event_time_end":"2011-11-16T16:30:00-05:00","event_time_end_last":"2011-11-16T16:30:00-05:00","gmt_time_start":"2011-11-16 19:30:00","gmt_time_end":"2011-11-16 21:30:00","gmt_time_end_last":"2011-11-16 21:30:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"related_links":[{"url":"http:\/\/ibb.gatech.edu\/QRB","title":"Quantitative Redox Biology Working Group Discussion"}],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"}],"categories":[],"keywords":[{"id":"1612","name":"BME"},{"id":"14838","name":"Dean Jones"},{"id":"14840","name":"Garry Buettner"},{"id":"248","name":"IBB"},{"id":"5084","name":"Melissa Kemp"},{"id":"14839","name":"Young-Mi Go"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1789","name":"Conference\/Symposium"}],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:melissa.kemp@bme.gatech.edu\u0022\u003EMelissa Kemp\u003C\/a\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}