{"693627":{"#nid":"693627","#data":{"type":"event","title":"PhD Defense by Sehyun Park","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003ESehyun Park\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003E(Advisor: Prof. Vladimir Tsukruk)\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003Ewill defend a doctoral thesis entitled,\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EEngineered Nanoscale Interfaces for\u0026nbsp;\u003C\/strong\u003E\u003Cbr\u003E\u003Cstrong\u003EElectrophysiological and Electrochemical Sensing\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cem\u003EOn\u003C\/em\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EThursday, November 12, 2026 at 9:00 a.m.\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EKrone Engineered biosystems building (EBB) 3029 Conference Room\u003C\/strong\u003E\u003Cbr\u003E\u003Cstrong\u003Eand\/or virtually via\u0026nbsp;\u003C\/strong\u003E\u003Ca href=\u0022https:\/\/teams.microsoft.com\/meet\/2487989163932812?p=IBouYh6DEQpQXpuRXx\u0022\u003E\u003Cstrong\u003EMS Teams\u003C\/strong\u003E\u003C\/a\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EAbstract\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003EThe signal quality of a sensing device is largely determined at the interface between the device and its target, a region typically less than a few hundred nm thick. In wearable electrophysiology, this interface must maintain contact with skin that deforms and perspires, whereas in trace-level chemical sensing it must discriminate analytes with few reactive functional groups. In both cases, the thickness and surface chemistry of the interface are usually dictated by the choice of material. This reserach presents two nanoscale interface platforms in which both parameters are defined at the design stage.\u003C\/p\u003E\u003Cp\u003EThe first platform is an ultrathin skin-conformal nano-electrode composed of Ti3C2Tx MXene (50 nm), poly-L-lysine, and parylene (\u2248300 nm), with the parylene thickness determined from a work-of-adhesion analysis of contact with skin texture. The hydrophilic MXene side and hydrophobic parylene side allow the film to be transferred onto skin by water-assisted capillary flow and to remain attached without gel or adhesive. Compared with commercial gel electrodes, the nano-electrode showed approximately 35% lower skin interfacial impedance and up to threefold higher signal-to-noise ratio in ECG and EMG. ECG was recorded in a sauna and a swimming pool, where gel electrodes detached within minutes, and stable recording was maintained over 30 h of continuous wear.\u003C\/p\u003E\u003Cp\u003EThe second platform is an extended-gate field-effect transistor (EGFET) for tertiary amines of the tryptamine family, with gramine as a structural surrogate for \u003Cem\u003EN\u003C\/em\u003E,\u003Cem\u003EN\u003C\/em\u003E\u2011dimethyltryptamine (DMT). Since these molecules have no N\u2013H bond and no useful redox activity, selectivity was introduced through chemical activation. Sequential \u003Cem\u003EN\u003C\/em\u003E\u2011oxidation and Polonovski rearrangement convert the tertiary amine into an amide, which is covalently bound to an amino-terminated self-assembled monolayer on the gold gate by transamidation, and the resulting surface-potential change is read by a commercial MOSFET. The sensor exhibited a limit of detection of 7 nM over four orders of magnitude. In artificial saliva, gramine was still activated in the presence of thiocyanate and urea, and the extraction step of the Polonovski reaction separated the amide from the matrix before surface coupling.\u003C\/p\u003E\u003Cp\u003EIn both platforms, a function normally supplied by an added layer was instead built into the interface itself by controlling its thickness and surface chemistry: water tolerance at the electrode and molecular selectivity at the gate.\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ECommittee\u003C\/strong\u003E\u003C\/p\u003E\u003Cul\u003E\u003Cli data-list-item-id=\u0022ecf0066c9c8cb444b62902592ce6fb300\u0022\u003EProf. Vladimir Tsukruk \u2013 School of Materials Science and Engineering (advisor)\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e37cae127771bd1c229bb17c78a6ce046\u0022\u003EProf. Eric Vogel \u2013 School of Materials Science and Engineering\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e77fee81fd7615019aca1a7f37330bf62\u0022\u003EProf. Shucong Li \u2013 School of Materials Science and Engineering\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e69a2e2467a9e90d76a6eda77f34c0d8d\u0022\u003EProf. Peter Hesketh \u2013\u0026nbsp;School of Mechanical Engineering\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e7e16ae503bf577037516b0e50a1fb882\u0022\u003EProf. Todd Sulchek \u2013 School of Mechanical Engineering\u003C\/li\u003E\u003C\/ul\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EEngineered Nanoscale Interfaces for\u0026nbsp;\u003Cbr\u003EElectrophysiological and Electrochemical Sensing\u003Cbr\u003E\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Engineered Nanoscale Interfaces for  Electrophysiological and Electrochemical Sensing"}],"uid":"27707","created_gmt":"2026-10-29 17:35:36","changed_gmt":"2026-10-29 17:37:54","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2026-11-12T09:00:00-05:00","event_time_end":"2026-11-12T11:00:00-05:00","event_time_end_last":"2026-11-12T11:00:00-05:00","gmt_time_start":"2026-11-12 14:00:00","gmt_time_end":"2026-11-12 16:00:00","gmt_time_end_last":"2026-11-12 16:00:00","rrule":null,"timezone":"America\/New_York"},"location":"Krone Engineered biosystems building (EBB) 3029 Conference Room and\/or virtually via MS Teams","extras":[],"groups":[{"id":"221981","name":"Graduate Studies"}],"categories":[],"keywords":[{"id":"100811","name":"Phd Defense"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"78771","name":"Public"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}