{"693305":{"#nid":"693305","#data":{"type":"event","title":"PhD Proposal  by  Sean Healy","body":[{"value":"\u003Cp\u003ESean Healy\u003Cbr\u003EBME PhD Proposal Presentation\u003Cbr\u003E\u003Cbr\u003EDate: 2026-10-28\u003Cbr\u003ETime: 10:00 am\u003Cbr\u003ELocation \/ Meeting Link: MoSE 3201A\u003Cbr\u003E\u003Cbr\u003ECommittee Members:\u003Cbr\u003ERafael Davalos, PhD; Matthew Flavin, PhD; Gary W. Liu, PhD; David R. Myers, PhD\u003Cbr\u003E\u003Cbr\u003E\u003Cbr\u003ETitle: Severable Ingestible Electronics for Facilitated GI Transit and Sensor-Guided Therapeutics\u003Cbr\u003E\u003Cbr\u003EAbstract:\u003Cbr\u003EIngestible electronics enable the unique tracking and treatment of gastrointestinal and systemic diseases. However, bulky batteries, circuit boards, and drug payloads require large capsule sizes that can result in bowel obstruction, a medical emergency. In this thesis, we engineer electronic pill capable of triggered severing into tiny 9 x 15 mm pieces with sizes clinically proven to reduce obstruction risk. Our capsules enable multicomponent circuit boards to connect with separately encapsulated powering elements via conductive, interlocking connections. Heat induced softening of polyethylene glycol\/polycaprolactone channels activates a spring to separate encapsulated components into inert 9 x 15 mm segments, facilitating intestinal passage. Separation triggers included manual activation via Bluetooth low energy, closed-loop sensors and time-delay circuits. In vivo swine studies demonstrate the ability of our capsules to sense luminal oxygen changes via an optoelectronic sensor, release therapeutic payloads on command, and facilitate safe excretion.\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003ESeverable Ingestible Electronics for Facilitated GI Transit and Sensor-Guided Therapeutics\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Severable Ingestible Electronics for Facilitated GI Transit and Sensor-Guided Therapeutics"}],"uid":"27707","created_gmt":"2026-10-19 18:17:12","changed_gmt":"2026-10-19 18:32:50","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2026-10-28T10:00:00-04:00","event_time_end":"2026-10-28T11:00:00-04:00","event_time_end_last":"2026-10-28T11:00:00-04:00","gmt_time_start":"2026-10-28 14:00:00","gmt_time_end":"2026-10-28 15:00:00","gmt_time_end_last":"2026-10-28 15:00:00","rrule":null,"timezone":"America\/New_York"},"location":"MoSE 3201A","extras":[],"groups":[{"id":"221981","name":"Graduate Studies"}],"categories":[],"keywords":[{"id":"102851","name":"Phd proposal"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"78771","name":"Public"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}