{"690455":{"#nid":"690455","#data":{"type":"event","title":"Southeastern Chemical Biology and Drug Design Symposium","body":[{"value":"\u003Cp\u003EThe Southeastern Chemical Biology and Drug Design Symposium will focus on the research frontiers of chemical biology, drug discovery and development, and molecular medicine and include cutting-edge research talks and poster presentations by a diverse group of faculty, post-doctoral scholars, graduate and undergraduate students.\u0026nbsp;\u003C\/p\u003E\u003Ch5\u003E\u003Cstrong\u003EImportant Deadlines\u003C\/strong\u003E\u003C\/h5\u003E\u003Cul\u003E\u003Cli data-list-item-id=\u0022eeb647109ce4a1d456299be393a2c2117\u0022\u003E\u003Cstrong\u003EAugust 7\u003C\/strong\u003E: Abstract Submission Deadline for podium and poster presentation consideration - \u003Ca href=\u0022https:\/\/gatech.infoready4.com\/#freeformCompetitionDetail\/2016861\u0022\u003E\u003Cstrong\u003ESubmit Here\u003C\/strong\u003E\u003C\/a\u003E\u003C\/li\u003E\u003Cli data-list-item-id=\u0022ea8fdfcfe2d2024c70c5f2703acb56491\u0022\u003E\u003Cstrong\u003ESeptember 8\u003C\/strong\u003E: Registration Deadline (required for all attendees) - \u003Ca href=\u0022https:\/\/epay.gatech.edu\/C20793_ustores\/web\/store_main.jsp?STOREID=624\u0026amp;SINGLESTORE=true\u0022\u003E\u003Cstrong\u003ERegister Here\u003C\/strong\u003E\u003C\/a\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003Cp\u003E\u003Ca href=\u0022https:\/\/epay.gatech.edu\/C20793_ustores\/web\/store_main.jsp?STOREID=624\u0022\u003E\u003Cem\u003E\u003Cstrong\u003EView sponsorship opportunities\u003C\/strong\u003E\u003C\/em\u003E\u003C\/a\u003E\u003C\/p\u003E\u003Ch5\u003E\u003Cstrong\u003ESymposium Agenda\u003C\/strong\u003E\u003C\/h5\u003E\u003Cul\u003E\u003Cli data-list-item-id=\u0022e889a3da770c38bab0e39ea40d00dfa3b\u0022\u003E7:30 a.m. \u0026nbsp; \u0026nbsp; Registration\/Breakfast\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e9f4521b3e1fa0a8fe94c600b5d895c35\u0022\u003E8:20 a.m. \u0026nbsp; \u0026nbsp; Opening Remarks and Welcome\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e4398f33de1311c27ebd16572c9e2a720\u0022\u003E8:30 a.m. \u0026nbsp; \u0026nbsp; Session One - \u003Cem\u003E5 speakers\u003C\/em\u003E\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e5665fda96e31b5bf0cabea8e01f35b50\u0022\u003E10:10 a.m. \u0026nbsp; Break\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e03faa1335a1c7d2cf4351f197ba773a2\u0022\u003E10:40 a.m. \u0026nbsp; Session Two - \u003Cem\u003E5 speakers\u003C\/em\u003E\u003C\/li\u003E\u003Cli data-list-item-id=\u0022ee1d9158f752dbb46726818325cdbef6a\u0022\u003E12:20 p.m. \u0026nbsp; Lunch\u003C\/li\u003E\u003Cli data-list-item-id=\u0022efe9351369e98ecebff2b3da7cbb61c72\u0022\u003E1:30 p.m. \u0026nbsp; \u0026nbsp; Session Three - \u003Cem\u003E4 speakers\u003C\/em\u003E\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e2935bc254da0726a38dac08e948bab36\u0022\u003E2:50 p.m. \u0026nbsp; \u0026nbsp; Break\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e02d5d05538353a2b93d4b983f4466c11\u0022\u003E3:10 p.m. \u0026nbsp; \u0026nbsp;\u0026nbsp;\u003Cstrong\u003EKeynote Presentation\u003C\/strong\u003E - \u003Cem\u003E\u0022A Novel Chemical Biology Platform for Deubiquitylases\u0022\u003C\/em\u003E - \u003Ca href=\u0022https:\/\/bcmp.hms.harvard.edu\/faculty-staff\/sara-buhrlage\u0022\u003E\u003Cstrong\u003ESara Buhrlage\u003C\/strong\u003E\u003C\/a\u003E, Harvard Medical School\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e73a59164b79746b8427cbedf352a8e83\u0022\u003E4:30 p.m. \u0026nbsp; \u0026nbsp; Poster Session and Networking Reception\u003C\/li\u003E\u003Cli data-list-item-id=\u0022eeed84bf467bc852144636f3524825d38\u0022\u003E6:30 p.m. \u0026nbsp; \u0026nbsp; Adjourn\u003C\/li\u003E\u003C\/ul\u003E\u003Cp\u003E\u003Cem\u003E\u003Cstrong\u003EKeynote Lecture:\u003C\/strong\u003E\u003C\/em\u003E\u003Cbr\u003E\u003Ca href=\u0022https:\/\/labs.dana-farber.org\/buhrlagelab\/\u0022\u003E\u003Cstrong\u003ESara Burlage\u003C\/strong\u003E\u003C\/a\u003E\u003Cbr\u003E\u003Cstrong\u003EAssociate Professor\u003C\/strong\u003E\u003Cbr\u003E\u003Cstrong\u003EDana-Farber Cancer Institute department of Cancer Biology\u003C\/strong\u003E\u003Cbr\u003E\u003Cstrong\u003EDepartment of Biological Chemistry and Molecular Pharmacology\u003C\/strong\u003E\u003Cbr\u003E\u003Cstrong\u003EHarvard Medical School\u003C\/strong\u003E\u003Cbr\u003E\u003Cbr\u003EABSTRACT\u003Cbr\u003EDeubiquitylases (DUBs) are a large family of enzymes that remove ubiquitin or ubiquitin chains from substrate proteins. Similar to other components of the UPS, DUBs have been associated with disease and pursued as drug targets. Despite enthusiasm around targeting DUBs both with inhibitors as well as DUBTACs, there remain unanswered fundamental questions around substrates and substrate scope as well as how DUBs work at a detailed mechanistic level. The overarching goal of our lab is to develop chemical tools that can be deployed to study basic function and translational potential of DUBs. Our platform integrates DUB library synthesis, medicinal chemistry, biochemistry, high-throughput screening, chemoproteomics, chemical genomics, structural biology, target validation and cancer biology. I will discuss recent discoveries enabled by our platform including new mechanism-of-action ligands for DUBs and their study in rare disease as well as new insights into DUB interplay with other components of the UPS.\u003C\/p\u003E\u003Cp\u003EBIO\u003Cbr\u003ESara Buhrlage is an Associate Professor holding joint appointments in the Dana-Farber Cancer Institute department of Cancer Biology and the Harvard Medical School department of Biological Chemistry and Molecular Pharmacology. Buhrlage is a leader in harnessing deubiquitylases (DUBs) as emergent drug targets, where her lab has pioneered new approaches for interrogating DUB function, new insights into the chemical tractability of DUBs, and mapping the therapeutic potential of DUBs in cancer. In addition to research, she is dedicated to graduate education, holding leadership roles in multiple graduate programs and teaching graduate level courses. More recently, she has become involved in biotech and company creation as a scientific founder of Entact Bio. Buhrlage earned a Doctor of Philosophy in organic chemistry from the University of Michigan and completed a post-doctoral fellowship at the Broad Institute.\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EFeaturing cutting-edge research talks on the frontiers of chemical biology, drug discovery and development, and molecular medicine.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Open to..."}],"uid":"35486","created_gmt":"2026-05-22 15:31:45","changed_gmt":"2026-07-13 14:47:30","author":"Christina Wessels","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2026-09-18T08:00:00-04:00","event_time_end":"2026-09-18T19:00:00-04:00","event_time_end_last":"2026-09-18T19:00:00-04:00","gmt_time_start":"2026-09-18 12:00:00","gmt_time_end":"2026-09-18 23:00:00","gmt_time_end_last":"2026-09-18 23:00:00","rrule":null,"timezone":"America\/New_York"},"location":"Marcus Nanotechnology Building - Conference room 1116-118","extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"},{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[{"id":"187423","name":"go-bio"},{"id":"189814","name":"go-researchevents"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1789","name":"Conference\/Symposium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"177814","name":"Postdoc"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:connect@ibb.gatech.edu\u0022\u003Econnect@ibb.gatech.edu\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}