{"690455":{"#nid":"690455","#data":{"type":"event","title":"Southeastern Chemical Biology and Drug Design Symposium","body":[{"value":"\u003Cp\u003EThe Southeastern Chemical Biology and Drug Design Symposium will focus on the research frontiers of chemical biology, drug discovery and development, and molecular medicine, this symposium will include cutting-edge research talks and poster presentations by a diverse group of faculty, post-doctoral scholars, graduate and undergraduate students.\u0026nbsp;\u003C\/p\u003E\u003Ch5\u003E\u003Cstrong\u003ERegistration Deadline\u003C\/strong\u003E\u003C\/h5\u003E\u003Cul\u003E\u003Cli data-list-item-id=\u0022ee04017bf4c6f80bf82d5b9443370c84b\u0022\u003E\u003Cstrong\u003ETuesday, Sept. 8 @ 11:59 ET\u003C\/strong\u003E \u003Cstrong\u003E-\u003C\/strong\u003E \u003Ca href=\u0022https:\/\/epay.gatech.edu\/C20793_ustores\/web\/store_main.jsp?STOREID=624\u0026amp;SINGLESTORE=true\u0022\u003E\u003Cstrong\u003ERegister Here\u003C\/strong\u003E\u003C\/a\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003Cp\u003E\u003Ca href=\u0022https:\/\/epay.gatech.edu\/C20793_ustores\/web\/store_main.jsp?STOREID=624\u0022\u003E\u003Cem\u003E\u003Cstrong\u003EView sponsorship opportunities\u003C\/strong\u003E\u003C\/em\u003E\u003C\/a\u003E\u003C\/p\u003E\u003Ch2\u003E\u003Cstrong\u003ESymposium Agenda\u003C\/strong\u003E\u003C\/h2\u003E\u003Ch6\u003E\u003Cstrong\u003ELocation: Marcus Nanotechnology Building, Rooms 1116-1118\u003C\/strong\u003E \u003Cem\u003E(unless otherwise noted)\u003C\/em\u003E\u003C\/h6\u003E\u003Cul\u003E\u003Cli data-list-item-id=\u0022e4bb53a502bc151eff8d34af0c37755d4\u0022\u003E\u003Cstrong\u003E7:30 a.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp; Check-in | Continental Breakfast\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e0355325167596a1f3c20b5346750a7d4\u0022\u003E\u003Cstrong\u003E8:20 a.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp; Welcome - Adegboyega Oyelere, Symposium Chair, Georgia Tech\u003C\/li\u003E\u003Cli data-list-item-id=\u0022ee758d40ecf247be8b5830fa29a4bd638\u0022\u003E\u003Cstrong\u003E8:25 a.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp; Opening Remarks - Vicki Wysocki, Chair, School of Chemistry and Biochemistry, Georgia Tech\u003C\/li\u003E\u003C\/ul\u003E\u003Ch5\u003E\u003Cstrong\u003ESession I - Oral Presentations\u003C\/strong\u003E\u003C\/h5\u003E\u003Ch6\u003EModerator: Tyler Beyett\u003C\/h6\u003E\u003Cul\u003E\u003Cli data-list-item-id=\u0022e26dfe4f307f632283b5bb456e172d722\u0022\u003E\u003Cstrong\u003E8:30 a.m.\u0026nbsp;\u003C\/strong\u003E \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022Targeting Highly Aggressive Cancers by Uncovering Druggable Vulnerabilities\u0022 \u003C\/em\u003E- Ozgur Sahin, Medical University of South Carolina\u003C\/li\u003E\u003Cli data-list-item-id=\u0022ed119ee5ab1de085bfdd92ea8f2d5950f\u0022\u003E\u003Cstrong\u003E8:50 a.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022Inhibition of Topoisomerase II\u03b1 Activity by Linker Histone H1\u0022\u003C\/em\u003E - Yuhong Fan, Georgia Institute of Technology\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e7428ab0d90a97cbda951484c2b75b862\u0022\u003E\u003Cstrong\u003E9:10 a.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022Neo-Cysteine Molecular Glues for Targeting Mutated SMAD4 Protein\u0022\u003C\/em\u003E - Pooja Kumari, Emory University\u003C\/li\u003E\u003Cli data-list-item-id=\u0022eee1c38858bf4f56cdbfd8a5e27471aae\u0022\u003E\u003Cstrong\u003E9:30 a.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022In Vivo Efficacy of Abbapolin Degraders of the PLK1 PBD and Synergy With Androgen Therapy in Prostate Cancer\u0022\u003C\/em\u003E - Shikha Kumari, University of South Carolina\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e8c98d3702413bed30ee86b9f52d9d6b1\u0022\u003E\u003Cstrong\u003E9:50 a.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022Cathepsin Inhibitor Suppresses the Growth of Ectopic Hepatocellular Carcinoma Tumors in Mouse Models\u0022\u003C\/em\u003E - Olamide Crown, Alabama A\u0026amp;M University\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e5fcd3513247352385697643182f13383\u0022\u003E\u003Cstrong\u003E10:10 a.m.\u003C\/strong\u003E \u0026nbsp; Break\u003C\/li\u003E\u003C\/ul\u003E\u003Ch5\u003E\u003Cstrong\u003ESession II - Oral Presentations\u003C\/strong\u003E\u003C\/h5\u003E\u003Ch6\u003EModerator: Campbell McInnes\u003C\/h6\u003E\u003Cul\u003E\u003Cli data-list-item-id=\u0022e49000f27ef449a191942bfae90594afb\u0022\u003E\u003Cstrong\u003E10:30 a.m.\u003C\/strong\u003E \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022Turning \u03b1-Amylase Activity Into Light: Polycyclic 1,2-BN-Heteroarene-Based AIE Supramolecular Nanocapsules for Biosensing\u0022\u003C\/em\u003E - Carl Saint-Louis, Kennesaw State University\u003C\/li\u003E\u003Cli data-list-item-id=\u0022ea5763ed85ace5a88506681284499dd7b\u0022\u003E\u003Cstrong\u003E10:50 a.m.\u0026nbsp;\u003C\/strong\u003E \u0026nbsp;\u003Cem\u003E\u0022Passive and Activatable Targeting of Near-Infrared Fluorophores for Tissue, Bone, Cartilage, and Disease Imaging in Image-Guided Surgery\u0022\u003C\/em\u003E - Maged Henary, Georgia State University \u0026nbsp;\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e711dd3a6014f95847260cf75f59781e0\u0022\u003E\u003Cstrong\u003E11:10 a.m.\u003C\/strong\u003E \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022Application of Natural and Semisynthetic Saponins in Biomedicine\u0022 \u003C\/em\u003E- Pengfei Wang, University of Alabama at Birmingham\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e529875e7c2c07192fcf986c4d3504b2c\u0022\u003E\u003Cstrong\u003E11:30 a.m.\u003C\/strong\u003E \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022FMCAP (DDG-002): A Potent Modified-Nucleotide Analog Against Monkeypox Virus (MPXV)\u0022\u003C\/em\u003E - Uma Singh, University of Georgia\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e596b0929438d3780af6c59edd956267d\u0022\u003E\u003Cstrong\u003E11:50 a.m.\u003C\/strong\u003E \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022Developing Ir(III)\/Ru(II) Bisterpyridine Complexes as Antimicrobial Photodynamic Therapeutic Agents\u0022\u003C\/em\u003E - Wenfang Sun, The University of Alabama\u0026nbsp;\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e8130f0d77b016468dff9db5ea750493a\u0022\u003E\u003Cstrong\u003E12:10 p.m.\u003C\/strong\u003E \u0026nbsp; Lunch - Petit Biotechnology Building (\u0022IBB\u0022) - \u003Cem\u003Enext door to Marcus Nanotech Bldg.\u003C\/em\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003Ch5\u003E\u003Cstrong\u003ESession III - Oral Presentations\u003C\/strong\u003E\u003C\/h5\u003E\u003Ch6\u003EModerator: Y. George Zheng\u003C\/h6\u003E\u003Cul\u003E\u003Cli data-list-item-id=\u0022e0843822f18c70ccc196747f881235eed\u0022\u003E\u003Cstrong\u003E1:20 p.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022Reactive Oxygen Species (ROS) Research: How Much Do We Really Know What Our Tools Are Measuring?\u0022\u003C\/em\u003E - Binghe Wang, Georgia State University\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e9b5327b31d78e71efed571d9a8b567a1\u0022\u003E\u003Cstrong\u003E1:40 p.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022A Compact Tag-Directed Platform Enables Rapid Targeted Protein Degradation\u0022\u003C\/em\u003E - \u0026nbsp;Dongwen Lyu, Augusta University\u003C\/li\u003E\u003Cli data-list-item-id=\u0022ea2feb972ae2c39d6b02919640313c708\u0022\u003E\u003Cstrong\u003E2:00 p.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022Optical Tools for Precisely Controlling Dopamine Receptors\u0022\u003C\/em\u003E - Prashant Donthamsetti, Vanderbilt University \u0026nbsp;\u0026nbsp;\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e3ad3ba5753937b9e3d11c90ab9af01b4\u0022\u003E\u003Cstrong\u003E2:20 p.m.\u0026nbsp;\u003C\/strong\u003E \u0026nbsp; \u0026nbsp;\u003Cem\u003E\u0022Advancing Lead Generation: Overcoming Selectivity Challenges With DNA-Encoded Libraries\u0022\u003C\/em\u003E - Srinivas Chamakuri, Baylor College of Medicine\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e436b8604b40ef6a16ac2c64a4e46f949\u0022\u003E\u003Cstrong\u003E2:40 p.m.\u0026nbsp;\u003C\/strong\u003E \u0026nbsp; \u0026nbsp;\u0026nbsp;\u003Cem\u003E\u0022Chemical Biology of Druggable Bacteria to combate Antibiotic-Resistant Pathogens\u0022\u003C\/em\u003E - Ashfaqul Alam, University of Kentucky\u003C\/li\u003E\u003Cli data-list-item-id=\u0022ea5f5a555ade9d6e943f0411b06b77a47\u0022\u003E\u003Cstrong\u003E3 p.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; Break\u003C\/li\u003E\u003C\/ul\u003E\u003Ch5\u003E\u003Cstrong\u003ESession IV - Keynote Lecture\u003C\/strong\u003E\u003C\/h5\u003E\u003Ch6\u003EModerator: Alex G. Waterson\u003C\/h6\u003E\u003Cul\u003E\u003Cli data-list-item-id=\u0022e14343844a0e5ff445a8bd386e04a1f4d\u0022\u003E\u003Cstrong\u003E3:15 p.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp;\u0026nbsp;\u003Cstrong\u003EKeynote Presentation\u003C\/strong\u003E \u003Cstrong\u003E- \u003C\/strong\u003E\u003Cem\u003E\u003Cstrong\u003E\u0022A Novel Chemical Biology Platform for Deubiquitylases\u0022\u003C\/strong\u003E\u003C\/em\u003E\u003Cstrong\u003E -\u003C\/strong\u003E \u003Ca href=\u0022https:\/\/bcmp.hms.harvard.edu\/faculty-staff\/sara-buhrlage\u0022\u003E\u003Cstrong\u003ESara Buhrlage\u003C\/strong\u003E\u003C\/a\u003E\u003Cstrong\u003E, Harvard Medical School*\u003C\/strong\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003Ch5\u003E\u003Cstrong\u003ESession V - Poster Session and Networking Reception\u003C\/strong\u003E\u003C\/h5\u003E\u003Ch6\u003EModerator: Victor Ogungbe\u003C\/h6\u003E\u003Cul\u003E\u003Cli data-list-item-id=\u0022ed8aabef5353c9d655565bfe1c8f2fbef\u0022\u003E\u003Cstrong\u003E4:30 p.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp; Odd-numbered posters\u003C\/li\u003E\u003Cli data-list-item-id=\u0022e946a1ffca6547f50e98e0690f11245b8\u0022\u003E\u003Cstrong\u003E5:40 p.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp; Even-numbered posters\u003C\/li\u003E\u003Cli data-list-item-id=\u0022ec33f906a750cc5dd84947704f509f010\u0022\u003E\u003Cstrong\u003E6:40 p.m.\u003C\/strong\u003E \u0026nbsp; \u0026nbsp; Adjourn\u003C\/li\u003E\u003C\/ul\u003E\u003Cp\u003E\u003Cem\u003E\u003Cstrong\u003E**********************************\u003C\/strong\u003E\u003C\/em\u003E\u003Cbr\u003E\u003Cbr\u003E\u003Cem\u003E\u003Cstrong\u003E*Keynote Lecture:\u003C\/strong\u003E\u003C\/em\u003E\u003Cbr\u003E\u003Ca href=\u0022https:\/\/labs.dana-farber.org\/buhrlagelab\/\u0022\u003E\u003Cstrong\u003ESara Burlage\u003C\/strong\u003E\u003C\/a\u003E\u003Cbr\u003E\u003Cstrong\u003EAssociate Professor\u003C\/strong\u003E\u003Cbr\u003E\u003Cstrong\u003EDana-Farber Cancer Institute department of Cancer Biology\u003C\/strong\u003E\u003Cbr\u003E\u003Cstrong\u003EDepartment of Biological Chemistry and Molecular Pharmacology\u003C\/strong\u003E\u003Cbr\u003E\u003Cstrong\u003EHarvard Medical School\u003C\/strong\u003E\u003Cbr\u003E\u003Cbr\u003EABSTRACT\u003Cbr\u003EDeubiquitylases (DUBs) are a large family of enzymes that remove ubiquitin or ubiquitin chains from substrate proteins. Similar to other components of the UPS, DUBs have been associated with disease and pursued as drug targets. Despite enthusiasm around targeting DUBs both with inhibitors as well as DUBTACs, there remain unanswered fundamental questions around substrates and substrate scope as well as how DUBs work at a detailed mechanistic level. The overarching goal of our lab is to develop chemical tools that can be deployed to study basic function and translational potential of DUBs. Our platform integrates DUB library synthesis, medicinal chemistry, biochemistry, high-throughput screening, chemoproteomics, chemical genomics, structural biology, target validation and cancer biology. I will discuss recent discoveries enabled by our platform including new mechanism-of-action ligands for DUBs and their study in rare disease as well as new insights into DUB interplay with other components of the UPS.\u003C\/p\u003E\u003Cp\u003EBIO\u003Cbr\u003ESara Buhrlage is an Associate Professor holding joint appointments in the Dana-Farber Cancer Institute department of Cancer Biology and the Harvard Medical School department of Biological Chemistry and Molecular Pharmacology. Buhrlage is a leader in harnessing deubiquitylases (DUBs) as emergent drug targets, where her lab has pioneered new approaches for interrogating DUB function, new insights into the chemical tractability of DUBs, and mapping the therapeutic potential of DUBs in cancer. In addition to research, she is dedicated to graduate education, holding leadership roles in multiple graduate programs and teaching graduate level courses. More recently, she has become involved in biotech and company creation as a scientific founder of Entact Bio. Buhrlage earned a Doctor of Philosophy in organic chemistry from the University of Michigan and completed a post-doctoral fellowship at the Broad Institute.\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Ch5\u003EFeaturing cutting-edge research talks on the frontiers of chemical biology, drug discovery and development, and molecular medicine.\u003C\/h5\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Featuring cutting-edge research talks on the frontiers of chemical biology, drug discovery and development, and molecular medicine."}],"uid":"35486","created_gmt":"2026-05-22 15:31:45","changed_gmt":"2026-09-14 19:10:58","author":"Christina Wessels","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2026-09-18T08:00:00-04:00","event_time_end":"2026-09-18T18:30:00-04:00","event_time_end_last":"2026-09-18T18:30:00-04:00","gmt_time_start":"2026-09-18 12:00:00","gmt_time_end":"2026-09-18 22:30:00","gmt_time_end_last":"2026-09-18 22:30:00","rrule":null,"timezone":"America\/New_York"},"location":"Marcus Nanotechnology Building - Conference room 1116-118","extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"},{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[{"id":"187423","name":"go-bio"},{"id":"189814","name":"go-researchevents"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1789","name":"Conference\/Symposium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"177814","name":"Postdoc"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:connect@ibb.gatech.edu\u0022\u003Econnect@ibb.gatech.edu\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}