{"689230":{"#nid":"689230","#data":{"type":"event","title":"IBB Seminar","body":[{"value":"\u003Cp\u003E\u003Cbr\u003E\u003Ca href=\u0022https:\/\/mbel.snu.ac.kr\/\u0022\u003ENoo Li Jeon\u003C\/a\u003E\u003Cbr\u003E\u003Cstrong\u003EProfessor\u003C\/strong\u003E\u003Cbr\u003E\u003Cstrong\u003EDepartment of Mechanical Engineering\u003C\/strong\u003E\u003Cbr\u003E\u003Cstrong\u003ESeoul National University, Korea\u003C\/strong\u003E\u003Cbr\u003E\u003Cbr\u003ERecent advances in microphysiological systems (MPS) research have enabled the reconstruction of biomimetic 3D cellular microenvironments. However, significant challenges remain in generating reproducible vascularized micro-tissue constructs at scale. This presentation introduces an injection-molded plastic array platform and 3D-printed devices that support diverse MPS applications within a single, universal culture framework, with emphasis on vascularized spheroids and organoids.\u003Cbr\u003E\u003Cbr\u003EThe platform integrates spheroid and vascular network regions within a standard SLAS\/SBS form factor. A novel capillary-based patterning method allows stable, multi-channel loading of cell suspensions or cell-laden hydrogels. We demonstrate the platform\u0027s ability to reconstitute 3D tumor microenvironments, including angiogenesis, vascularized tumor models, and tumor, immune cell migration.\u003Cbr\u003E\u003Cbr\u003ECritically, the platform is designed for high-throughput production of large numbers of near-identical microtissues that closely mimic the human 3D microenvironment. This scalability enables the generation of rich, reproducible datasets \u2014 an important resource for machine learning model training and a foundational axis for AI-driven drug discovery pipelines. The modular design can be rapidly customized to support a range of co-culture configurations, from tumor microenvironment modeling to vascularized organoids, positioning the platform as a key enabler of next-generation, data-intensive therapeutic screening.\u003Cbr\u003E\u003Cbr\u003E\u003Ca href=\u0022mailto:susan.thomas@me.gatech.edu\u0022\u003ESusan Thomas\u003C\/a\u003E, faculty host\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003E\u0022High-throughput Vascularized Organoids for Drug Discovery\u0022 - Noo Li Jeon, Seoul National University, Korea\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"\u0022High-throughput Vascularized Organoids for Drug Discovery\u0022 - Noo Li Jeon, Seoul National University, Korea"}],"uid":"27195","created_gmt":"2026-03-30 14:11:52","changed_gmt":"2026-04-17 11:51:43","author":"Colly Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2026-05-26T11:00:00-04:00","event_time_end":"2026-05-26T12:00:00-04:00","event_time_end_last":"2026-05-26T12:00:00-04:00","gmt_time_start":"2026-05-26 15:00:00","gmt_time_end":"2026-05-26 16:00:00","gmt_time_end_last":"2026-05-26 16:00:00","rrule":null,"timezone":"America\/New_York"},"location":"Petit Biotechnology Building (IBB), 315 Ferst Drive NW, Suddath Seminar Room 1128, Atlanta, GA 30332","extras":[],"groups":[{"id":"1292","name":"Parker H. Petit Institute for Bioengineering and Bioscience (IBB)"},{"id":"1254","name":"Wallace H. Coulter Dept. of Biomedical Engineering"}],"categories":[],"keywords":[{"id":"187423","name":"go-bio"},{"id":"189814","name":"go-researchevents"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"194683","name":"Talk"},{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"194945","name":"Alumni"},{"id":"78761","name":"Faculty\/Staff"},{"id":"177814","name":"Postdoc"},{"id":"78771","name":"Public"},{"id":"174045","name":"Graduate students"},{"id":"78751","name":"Undergraduate students"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:connect@ibb.gatech.edu\u0022\u003Econnect@ibb.gatech.edu\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}