{"685418":{"#nid":"685418","#data":{"type":"external_news","title":"A first of its kind C. elegans study uncovers the diversity and evolution of gene regulation","body":[{"value":"\u003Cp dir=\u0022ltr\u0022\u003EA team of researchers from the\u0026nbsp;\u003Ca href=\u0022https:\/\/biosciences.gatech.edu\/\u0022\u003ESchool of Biological Sciences\u003C\/a\u003E found some answers to the mystery of gene regulation by turning to the trusty roundworm\u0026nbsp;\u003Cem\u003EC. elegans\u003C\/em\u003E, a frequently studied model organism that has contributed to many important discoveries. In their new\u0026nbsp;\u003Ca href=\u0022https:\/\/academic.oup.com\/genetics\/advance-article-abstract\/doi\/10.1093\/genetics\/iyaf110\/8159564?redirectedFrom=fulltext\u0022\u003Estudy\u003C\/a\u003E published in\u0026nbsp;\u003Cem\u003EGENETICS\u003C\/em\u003E, the researchers used a powerful new approach to compare gene activity across several types of wildly diverse worm strains from all over the world to uncover their regulatory structure.\u003C\/p\u003E\u003Cp dir=\u0022ltr\u0022\u003EIn this first of its kind study, the researchers crossed each strain of worm with their standard N2 lab strain to make a hybrid offspring. They then used a modern and powerful technique called allele-specific RNA sequencing to determine how the genes were being used in these new strains, and which parent DNA is driving the gene\u2019s activity.\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp dir=\u0022ltr\u0022\u003EA team of researchers from the\u0026nbsp;\u003Ca href=\u0022https:\/\/biosciences.gatech.edu\/\u0022\u003ESchool of Biological Sciences\u003C\/a\u003E found some answers to the mystery of gene regulation by turning to the trusty roundworm\u0026nbsp;\u003Cem\u003EC. elegans\u003C\/em\u003E, a frequently studied model organism that has contributed to many important discoveries. In their new\u0026nbsp;\u003Ca href=\u0022https:\/\/academic.oup.com\/genetics\/advance-article-abstract\/doi\/10.1093\/genetics\/iyaf110\/8159564?redirectedFrom=fulltext\u0022\u003Estudy\u003C\/a\u003E published in\u0026nbsp;\u003Cem\u003EGENETICS\u003C\/em\u003E, the researchers used a powerful new approach to compare gene activity across several types of wildly diverse worm strains from all over the world to uncover their regulatory structure.\u003C\/p\u003E\u003Cp dir=\u0022ltr\u0022\u003EIn this first of its kind study, the researchers crossed each strain of worm with their standard N2 lab strain to make a hybrid offspring. They then used a modern and powerful technique called allele-specific RNA sequencing to determine how the genes were being used in these new strains, and which parent DNA is driving the gene\u2019s activity.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":"","uid":"36583","created_gmt":"2025-09-30 21:32:54","changed_gmt":"2025-10-01 19:52:24","author":"lvidal7","boilerplate_text":"","field_publication":"","publication":"Genes to Genomes","field_article_url":"","publication_url":"https:\/\/genestogenomes.org\/a-first-of-its-kind-c-elegans-study-uncovers-the-diversity-and-evolution-of-gene-regulation\/","dateline":{"date":"2025-08-15T00:00:00-04:00","iso_date":"2025-08-15T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1278","name":"College of Sciences"},{"id":"1275","name":"School of Biological Sciences"}],"categories":[{"id":"146","name":"Life Sciences and Biology"},{"id":"135","name":"Research"},{"id":"134","name":"Student and Faculty"}],"keywords":[{"id":"4896","name":"College of Sciences"},{"id":"166882","name":"School of Biological Sciences"},{"id":"6335","name":"Gene Regulation"},{"id":"192250","name":"cos-microbial"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}