{"682433":{"#nid":"682433","#data":{"type":"news","title":"Painting a Target on Cancer to Make Therapy More Effective","body":[{"value":"\u003Cp\u003EBiomedical engineers at Georgia Tech created a treatment that could one day unlock a universal strategy for treating some of the hardest-to-treat cancers \u2014 like those in the brain, breast, and colon \u2014 by teaching the immune system to see what it usually misses.\u003C\/p\u003E\u003Cp\u003ETheir experimental approach worked against those kinds of cancers in lab tests and didn\u2019t damage healthy tissues. Importantly, it also stopped cancer from returning.\u003C\/p\u003E\u003Cp\u003EWhile the therapy is still in early stages of development, it builds on well established, safe technologies, giving the treatment a clearer, quicker path to clinical trials and patient care.\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1038\/s43018-025-00968-5\u0022\u003EReported in May in the journal \u003Cem\u003ENature Cancer\u003C\/em\u003E\u003C\/a\u003E, their technique is a one-two punch that flags tumor cells so they can be recognized and then eliminated by specially enhanced T cells from the patient\u2019s own immune system.\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022https:\/\/coe.gatech.edu\/news\/2025\/05\/painting-target-cancer-make-therapy-more-effective\u0022\u003E\u003Cstrong\u003EGet all the details on the College of Engineering website.\u003C\/strong\u003E\u003C\/a\u003E\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EA BME team is putting a synthetic flag on tumors, then engineering a patient\u2019s immune cells to find and eliminate cancer.\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"A BME team is putting a synthetic flag on tumors, then engineering a patient\u2019s immune cells to find and eliminate cancer."}],"uid":"27446","created_gmt":"2025-05-16 18:09:10","changed_gmt":"2025-05-19 12:10:07","author":"Joshua Stewart","boilerplate_text":"","field_publication":"","field_article_url":"","location":"Atlanta, GA","dateline":{"date":"2025-05-19T00:00:00-04:00","iso_date":"2025-05-19T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"hg_media":{"677086":{"id":"677086","type":"image","title":"Cancer-target-synthetic-antigen-car-t-cell-therapy-3623-h.jpg","body":"\u003Cp\u003EThe combination approach that Lena Gamboa, seated, Gabe Kwong, foreground, and Ali Zamat developed tags the tumors with a synthetic \u0022flag\u0022 then uses specially engineered cells from the patient\u0027s own immune system to attack the cancer. They found their approach worked against hard-to-treat breast, brain, and colon cancers. it also turned the cancer into an immune system training ground, allowing the body to recognize and fight any tumors that regrow. (Photo: Candler Hobbs)\u003C\/p\u003E","created":"1747418961","gmt_created":"2025-05-16 18:09:21","changed":"1747418961","gmt_changed":"2025-05-16 18:09:21","alt":"Lena Gamboa and Gabe Kwong look at colorized cells on a computer monitor while Ali Zamat loads samples into a cell counting device. (Photo: Candler Hobbs)","file":{"fid":"260950","name":"Cancer-target-synthetic-antigen-car-t-cell-therapy-3623-h.jpg","image_path":"\/sites\/default\/files\/2025\/05\/16\/Cancer-target-synthetic-antigen-car-t-cell-therapy-3623-h.jpg","image_full_path":"http:\/\/hg.gatech.edu\/\/sites\/default\/files\/2025\/05\/16\/Cancer-target-synthetic-antigen-car-t-cell-therapy-3623-h.jpg","mime":"image\/jpeg","size":653815,"path_740":"http:\/\/hg.gatech.edu\/sites\/default\/files\/styles\/740xx_scale\/public\/2025\/05\/16\/Cancer-target-synthetic-antigen-car-t-cell-therapy-3623-h.jpg?itok=t1veEuar"}}},"media_ids":["677086"],"groups":[{"id":"1237","name":"College of Engineering"},{"id":"1214","name":"News Room"},{"id":"1188","name":"Research Horizons"}],"categories":[],"keywords":[{"id":"108041","name":"Gabe Kwong"},{"id":"188668","name":"CAR T-Cells"},{"id":"2470","name":"cancer therapy"},{"id":"187423","name":"go-bio"},{"id":"187915","name":"go-researchnews"}],"core_research_areas":[{"id":"39441","name":"Bioengineering and Bioscience"}],"news_room_topics":[{"id":"71891","name":"Health and Medicine"}],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Ca href=\u0022mailto:jstewart@gatech.edu\u0022\u003EJoshua Stewart\u003C\/a\u003E\u003Cbr\u003ECollege of Engineering\u003C\/p\u003E","format":"limited_html"}],"email":["jstewart@gatech.edu"],"slides":[],"orientation":[],"userdata":""}}}