{"680528":{"#nid":"680528","#data":{"type":"event","title":"PhD Proposal by Young Jae Ryu","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EYoung Jae Ryu\u003C\/strong\u003E\u003Cbr\u003E\u003Cstrong\u003EBioE PhD Proposal Presentation\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ETime and Date:\u003C\/strong\u003E 9:30 AM, February 28, 2025\u003Cbr\u003E\u003Cstrong\u003ELocation:\u003C\/strong\u003E CHOA Seminar Room, EBB Building\u003Cbr\u003E\u003Cstrong\u003EMicrosoft Teams Link:\u003C\/strong\u003E \u003Ca href=\u0022https:\/\/teams.microsoft.com\/l\/meetup-join\/19%3ameeting_ODU5M2QwMTUtYTNiMS00YmI4LTlhNWYtY2ExNDYxYTZkMDdi%40thread.v2\/0?context=%7b%22Tid%22%3a%22482198bb-ae7b-4b25-8b7a-6d7f32faa083%22%2c%22Oid%22%3a%22e2da635a-f687-4ed3-8284-7b5201df1a5e%22%7d\u0022 target=\u0022_new\u0022\u003EJoin the Meeting\u003C\/a\u003E\u003Cbr\u003E\u003Cstrong\u003EMeeting ID:\u003C\/strong\u003E 249 794 593 85\u003Cbr\u003E\u003Cstrong\u003EPasscode:\u003C\/strong\u003E F5De2Ch6\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EAdvisor:\u003C\/strong\u003E\u003Cbr\u003EDr. Brandon Dixon, Mechanical Engineering, Georgia Institute of Technology\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EThesis Committee:\u003C\/strong\u003E\u003Cbr\u003EDr. Alexander Alexeev, Mechanical Engineering, Georgia Institute of Technology\u003Cbr\u003EDr. Rudolph Gleason, Mechanical Engineering, Georgia Institute of Technology\u003Cbr\u003EDr. Susan Thomas, Mechanical Engineering, Georgia Institute of Technology\u003Cbr\u003EDr. Joseph Dayan, MD, MBA, Plastic \u0026amp; Reconstructive Surgeon, Board Certified in Plastic Surgery, Institute for Advanced Reconstruction\u003C\/p\u003E\u003Cp\u003E\u003Cbr\u003E\u003Cstrong\u003EModeling Lymphatic System Dynamics: Experimental and Computational Approaches to Lymphedema Treatment\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003ELymphedema is a debilitating condition caused by impaired lymphatic drainage, leading to chronic swelling and tissue damage. Despite its widespread prevalence, effective treatment options remain limited due to an incomplete understanding of the lymphatic system\u2019s physiological responses to injury and treatment interventions. This thesis aims to bridge this knowledge gap by integrating experimental and clinical approaches with computational modeling to explore lymphatic function and remodeling. This work is structured around three specific aims. \u003Cstrong\u003EAim 1\u003C\/strong\u003E focuses on a large-animal study using a sheep model to characterize the growth and remodeling of lymphatic vessels following injury. By combining in-vivo imaging, ex-vivo vessel analysis, and mechanical modeling, this study will provide critical insights into the contractile dynamics and adaptive responses of lymphatic vessels under mechanical stress. \u003Cstrong\u003EAim 2\u003C\/strong\u003E develops a lumped parameter model to simulate lymphaticovenous anastomoses (LVA), a microsurgical intervention for lymphedema, assessing how different configurations influence lymphatic transport efficiency. \u003Cstrong\u003EAim 3\u003C\/strong\u003E integrates growth and remodeling responses into the computational model to predict long-term LVA adaptations under varying mechanical loads. By linking experimental observations with computational simulations, this research aims to advance our understanding of lymphatic adaptation mechanisms and inform the development of LVA treatment for lymphedema. The findings will contribute to the refinement of LVA techniques and provide a foundation for future studies on lymphedema interventions.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003E\u003Cstrong\u003EModeling Lymphatic System Dynamics: Experimental and Computational Approaches to Lymphedema Treatment\u003C\/strong\u003E\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Modeling Lymphatic System Dynamics: Experimental and Computational Approaches to Lymphedema Treatment"}],"uid":"27707","created_gmt":"2025-02-17 15:07:41","changed_gmt":"2025-02-17 15:23:56","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2025-02-28T09:30:55-05:00","event_time_end":"2025-02-28T11:30:00-05:00","event_time_end_last":"2025-02-28T11:30:00-05:00","gmt_time_start":"2025-02-28 14:30:55","gmt_time_end":"2025-02-28 16:30:00","gmt_time_end_last":"2025-02-28 16:30:00","rrule":null,"timezone":"America\/New_York"},"location":"CHOA Seminar Room, EBB Building","extras":[],"groups":[{"id":"221981","name":"Graduate Studies"}],"categories":[],"keywords":[{"id":"102851","name":"Phd proposal"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"78771","name":"Public"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}