{"679199":{"#nid":"679199","#data":{"type":"external_news","title":"New Technology \u0027Sees\u0027 How Cholesterol Causes Heart Attacks","body":[{"value":"\u003Cp\u003EIn an article published in \u003Ca href=\u0022https:\/\/medicalxpress.com\/news\/2024-12-technology-cholesterol-heart.html\u0022\u003E\u003Cem\u003EMedical Xpress\u003C\/em\u003E\u003C\/a\u003E, Georgia Tech researchers from the \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\/\u0022\u003ESchool of Chemistry and Biochemistry\u003C\/a\u003E discussed the cryo-electron microscopy technology behind an important research discovery that could help create new drugs to lower \u0022bad\u0022 cholesterol and hopefully prevent heart attacks and stroke.\u003C\/p\u003E\u003Cp\u003EAssociate Professor \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\/people\/aditi-das\u0022\u003EAditi Das\u003C\/a\u003E and Professor \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\/people\/mg-finn\u0022\u003EMG Finn\u003C\/a\u003E explained in an email that cryo-electron microscopy technology represents a revolution in biology and biochemistry because it allows scientists to determine the structures of biological molecules in great detail.\u003C\/p\u003E\u003Cp\u003E\u0022When we know their structures, we have a big clue as to how they work, how to fix them if they are defective, or how to stop them if they cause harm. Nature is the supreme molecular architect, and we need techniques like cryo-EM to see the details of what she builds,\u0022 Finn explained.\u003C\/p\u003E\u003Cp\u003EResearch with this tool is going to have serious health benefits, the NIH said, because it allowed them for the first time to see how \u0022bad\u0022 cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body, and causes heart attacks and strokes in people who have genetically high LDL cholesterol.\u003C\/p\u003E\u003Cp\u003E(This story also appeared in the \u003Ca href=\u0022https:\/\/www.ajc.com\/news\/health-news\/breakthrough-technology-sees-how-cholesterol-causes-heart-attacks\/D4LU2XQFJFHADHAA5NLTZE5ZGY\/\u0022\u003EAtlanta Journal and Constitution\u003C\/a\u003E.)\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EIn an article published in \u003Ca href=\u0022https:\/\/medicalxpress.com\/news\/2024-12-technology-cholesterol-heart.html\u0022\u003E\u003Cem\u003EMedical Xpress\u003C\/em\u003E\u003C\/a\u003E, Georgia Tech researchers from the \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\/\u0022\u003ESchool of Chemistry and Biochemistry\u003C\/a\u003E discussed the cryo-electron microscopy technology behind an important research discovery that could help create new drugs to lower \u0022bad\u0022 cholesterol and hopefully prevent heart attacks and stroke.\u003C\/p\u003E\u003Cp\u003EAssociate Professor \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\/people\/aditi-das\u0022\u003EAditi Das\u003C\/a\u003E and Professor \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\/people\/mg-finn\u0022\u003EMG Finn\u003C\/a\u003E explained in an email that cryo-electron microscopy technology represents a revolution in biology and biochemistry because it allows scientists to determine the structures of biological molecules in great detail.\u003C\/p\u003E\u003Cp\u003E\u0022When we know their structures, we have a big clue as to how they work, how to fix them if they are defective, or how to stop them if they cause harm. Nature is the supreme molecular architect, and we need techniques like cryo-EM to see the details of what she builds,\u0022 Finn explained.\u003C\/p\u003E\u003Cp\u003EResearch with this tool is going to have serious health benefits, the NIH said, because it allowed them for the first time to see how \u0022bad\u0022 cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body, and causes heart attacks and strokes in people who have genetically high LDL cholesterol.\u003C\/p\u003E\u003Cp\u003E(This story also appeared in the \u003Ca href=\u0022https:\/\/www.ajc.com\/news\/health-news\/breakthrough-technology-sees-how-cholesterol-causes-heart-attacks\/D4LU2XQFJFHADHAA5NLTZE5ZGY\/\u0022\u003EAtlanta Journal and Constitution\u003C\/a\u003E.)\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":"","uid":"36607","created_gmt":"2025-01-06 18:40:18","changed_gmt":"2025-01-08 19:52:25","author":"ls67","boilerplate_text":"","field_publication":"","publication":"Medical Xpress","field_article_url":"","publication_url":"https:\/\/medicalxpress.com\/news\/2024-12-technology-cholesterol-heart.html","dateline":{"date":"2024-12-31T00:00:00-05:00","iso_date":"2024-12-31T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1278","name":"College of Sciences"},{"id":"85951","name":"School of Chemistry and Biochemistry"}],"categories":[{"id":"138","name":"Biotechnology, Health, Bioengineering, Genetics"},{"id":"141","name":"Chemistry and Chemical Engineering"}],"keywords":[{"id":"5926","name":"Molecules"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}