{"678908":{"#nid":"678908","#data":{"type":"external_news","title":"BioDolphin as a comprehensive database of lipid\u2013protein binding interactions","body":[{"value":"\u003Cp\u003ELipid-protein interactions are crucial for virtually all biological processes in living cells. However, existing structural databases focusing on these interactions are limited to integral membrane proteins. A systematic understanding of diverse lipid-protein interactions also encompassing lipid-anchored, peripheral membrane and soluble lipid binding proteins remains to be elucidated.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003ETo address this gap and facilitate the research of universal lipid-protein assemblies, researchers including \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\u0022\u003ESchool of Chemistry and Biochemistry\u003C\/a\u003E Assistant Professor \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\/people\/andrew-mcshan\u0022\u003EAndrew C. McShan\u003C\/a\u003E developed \u003Ca href=\u0022http:\/\/www.biodolphin.chemistry.gatech.edu\u0022\u003EBioDolphin\u003C\/a\u003E \u2014 a curated database with over 127,000 lipid-protein interactions. BioDolphin provides comprehensive annotations, including protein functions, protein families, lipid classifications, lipid-protein binding affinities, membrane association type, and atomic structures.\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003ELipid-protein interactions are crucial for virtually all biological processes in living cells. However, existing structural databases focusing on these interactions are limited to integral membrane proteins. A systematic understanding of diverse lipid-protein interactions also encompassing lipid-anchored, peripheral membrane and soluble lipid binding proteins remains to be elucidated.\u0026nbsp;\u003C\/p\u003E\u003Cp\u003ETo address this gap and facilitate the research of universal lipid-protein assemblies, researchers including \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\u0022\u003ESchool of Chemistry and Biochemistry\u003C\/a\u003E Assistant Professor \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\/people\/andrew-mcshan\u0022\u003EAndrew C. McShan\u003C\/a\u003E developed \u003Ca href=\u0022http:\/\/www.biodolphin.chemistry.gatech.edu\u0022\u003EBioDolphin\u003C\/a\u003E \u2014 a curated database with over 127,000 lipid-protein interactions. BioDolphin provides comprehensive annotations, including protein functions, protein families, lipid classifications, lipid-protein binding affinities, membrane association type, and atomic structures.\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":"","uid":"36583","created_gmt":"2024-12-16 18:20:07","changed_gmt":"2024-12-17 17:28:55","author":"lvidal7","boilerplate_text":"","field_publication":"","publication":"Communications Chemistry ","field_article_url":"","publication_url":"https:\/\/www.nature.com\/articles\/s42004-024-01384-z","dateline":{"date":"2024-12-04T00:00:00-05:00","iso_date":"2024-12-04T00:00:00-05:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1278","name":"College of Sciences"},{"id":"85951","name":"School of Chemistry and Biochemistry"}],"categories":[{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"135","name":"Research"},{"id":"134","name":"Student and Faculty"}],"keywords":[{"id":"4896","name":"College of Sciences"},{"id":"166928","name":"School of Chemistry and Biochemistry"},{"id":"194128","name":"BioDolphin"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}