{"675198":{"#nid":"675198","#data":{"type":"event","title":"PhD Defense by Aawaz Pokhrel ","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003ESchool of Physics Thesis Dissertation Defense\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EPresenter\u003C\/strong\u003E:\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp; Aawaz Pokhrel\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ETitle\u003C\/strong\u003E:\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp; Biophysical basis of bacterial colony growth\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EDate\u003C\/strong\u003E:\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp; Thursday, June 27, 2024\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ETime\u003C\/strong\u003E:\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp; 10:00 a.m. \u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ELocation\u003C\/strong\u003E:\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp; Howey Physics Building, N201\/202\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EVirtual link\u003C\/strong\u003E:\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp; \u003Ca href=\u0022https:\/\/gatech.zoom.us\/j\/93911211652\u0022\u003Ehttps:\/\/gatech.zoom.us\/j\/93911211652\u003C\/a\u003E\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u0026nbsp;\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003Cstrong\u003ECommittee members\u003C\/strong\u003E:\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EDr. Peter J. Yunker, School of Physics, Georgia Institute of Technology\u0026nbsp; (Advisor)\u003C\/p\u003E\u003Cp\u003EDr. Jennifer Curtis, School of Physics, Georgia Institute of Technology\u003C\/p\u003E\u003Cp\u003EDr. Brian K. Hammer, School of Biological Science, Georgia Institute of Technology\u003C\/p\u003E\u003Cp\u003EDr. Itamar Kolvin, School of Physics, Georgia Institute of Technology\u003C\/p\u003E\u003Cp\u003EDr. Zeb Rocklin, School of Physics, Georgia Institute of Technology\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003E\u0026nbsp;\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EAbstract\u003C\/strong\u003E:\u003C\/p\u003E\u003Cp\u003EBacteria often attach to surfaces and grow densely-packed communities called biofilms. As biofilms grow, they expand across the surface, granting them more access to nutrients. Thus, the overall growth rate of a biofilm is directly dependent on its \u0022range expansion\u0022 rate. While individual-based discrete models and continuum models have provided valuable insights into biofilm development, a quantitative understanding and experimental validation of basic vertical and horizontal growth are still lacking.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\u003Cp\u003EIn this thesis, we address this issue directly by experimentally observing the growth dynamics and morphologies of biofilms using interferometry. The use of interferometry allowed us to measure biofilm topography with nanometer resolution out-of-plane, providing insights into the emergent dynamics and morphologies of microbial colonies. We found that the geometry of the exponentially growing edge of a biofilm can be well described by a spherical-cap-napkin-ring geometry. We present a robust analysis of this geometry, showing the exact expression for the growth of such geometry explaining the growth of a biofilm. We then show that a simple biophysical model connecting vertical and horizontal growth dynamics can reproduce the experimental observations, suggesting that the spherical cap and spherical-cap-napkin-ring shapes emerge due to the biophysical consequences of diffusion-limited growth.\u003C\/p\u003E\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EBiophysical basis of bacterial colony growth\u0026nbsp;\u0026nbsp;\u003C\/p\u003E","format":"limited_html"}],"field_summary_sentence":[{"value":"Biophysical basis of bacterial colony growth  "}],"uid":"27707","created_gmt":"2024-06-24 19:10:51","changed_gmt":"2024-06-24 19:11:20","author":"Tatianna Richardson","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2024-06-27T10:00:00-04:00","event_time_end":"2024-06-27T12:00:00-04:00","event_time_end_last":"2024-06-27T12:00:00-04:00","gmt_time_start":"2024-06-27 14:00:00","gmt_time_end":"2024-06-27 16:00:00","gmt_time_end_last":"2024-06-27 16:00:00","rrule":null,"timezone":"America\/New_York"},"location":"Howey Physics Building, N201\/202","extras":[],"groups":[{"id":"221981","name":"Graduate Studies"}],"categories":[],"keywords":[{"id":"100811","name":"Phd Defense"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1788","name":"Other\/Miscellaneous"}],"invited_audience":[{"id":"78771","name":"Public"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}