674385 external_news 1714070787 1714499776 In a new study, published in GEN Biotechnology titled, “Changes in Gene Network Interactions in Breast Cancer Onset and Development,” researchers from the School of Biological Sciences and the Integrated Cancer Research Center (Zainab Arshad, Stephen N. Housley, Kara Keun Lee, and John F. McDonald) have identified differential gene-network changes characteristic of the three most prevalent molecular subtypes of breast cancer, Luminal A, Luminal B, and the highly metastatic Basal-like subtype. In contrast to previous studies, the authors expanded their analysis beyond genes differentially expressed between normal and cancer samples, as differential gene expression may not be a prerequisite for changes in gene-gene interactions. (This story also appeared at Medical Xpress and Mirage News.)

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