{"674385":{"#nid":"674385","#data":{"type":"external_news","title":"Gene Network Interactions Shed Insight into Breast Cancer Onset and Development","body":[{"value":"\u003Cp\u003EIn a new study, published in \u003Cem\u003EGEN Biotechnology\u003C\/em\u003E titled, \u201cChanges in Gene Network Interactions in Breast Cancer Onset and Development,\u201d researchers from the \u003Ca href=\u0022https:\/\/biosciences.gatech.edu\u0022\u003ESchool of Biological Sciences\u003C\/a\u003E and the \u003Ca href=\u0022https:\/\/icrc.gatech.edu\u0022\u003EIntegrated Cancer Research Center\u003C\/a\u003E\u0026nbsp;(\u003Ca href=\u0022https:\/\/bioinformatics.gatech.edu\/zainab-arshad\u0022\u003EZainab Arshad\u003C\/a\u003E,\u0026nbsp;\u003Ca href=\u0022https:\/\/cos.gatech.edu\/news\/postdoctoral-scientist-named-first-mccallum-early-career-fellow\u0022\u003EStephen N. Housley\u003C\/a\u003E, \u003Ca href=\u0022https:\/\/bioinformatics.gatech.edu\/kara-keun-lee\u0022\u003EKara Keun Lee\u003C\/a\u003E, and \u003Ca href=\u0022https:\/\/biosciences.gatech.edu\/people\/john-mcdonald\u0022\u003EJohn F. McDonald\u003C\/a\u003E) have identified differential gene-network changes characteristic of the three most prevalent molecular subtypes of breast cancer, Luminal A, Luminal B, and the highly metastatic Basal-like subtype. In contrast to previous studies, the authors expanded their analysis beyond genes differentially expressed between normal and cancer samples, as differential gene expression may not be a prerequisite for changes in gene-gene interactions.\u0026nbsp;(This story also appeared at \u003Ca href=\u0022https:\/\/medicalxpress.com\/news\/2024-04-gene-networks-aggressive-breast-cancer.html\u0022\u003EMedical Xpress\u003C\/a\u003E and\u0026nbsp;\u003Ca href=\u0022https:\/\/www.miragenews.com\/novel-gene-networks-linked-to-aggressive-breast-1220891\/\u0022\u003EMirage News\u003C\/a\u003E.)\u003C\/p\u003E\r\n","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EIn a new study, published in \u003Cem\u003EGEN Biotechnology\u003C\/em\u003E titled, \u201cChanges in Gene Network Interactions in Breast Cancer Onset and Development,\u201d researchers from the \u003Ca href=\u0022https:\/\/biosciences.gatech.edu\u0022\u003ESchool of Biological Sciences\u003C\/a\u003E and the \u003Ca href=\u0022https:\/\/icrc.gatech.edu\u0022\u003EIntegrated Cancer Research Center\u003C\/a\u003E\u0026nbsp;(\u003Ca href=\u0022https:\/\/bioinformatics.gatech.edu\/zainab-arshad\u0022\u003EZainab Arshad\u003C\/a\u003E,\u0026nbsp;\u003Ca href=\u0022https:\/\/cos.gatech.edu\/news\/postdoctoral-scientist-named-first-mccallum-early-career-fellow\u0022\u003EStephen N. Housley\u003C\/a\u003E, \u003Ca href=\u0022https:\/\/bioinformatics.gatech.edu\/kara-keun-lee\u0022\u003EKara Keun Lee\u003C\/a\u003E, and \u003Ca href=\u0022https:\/\/biosciences.gatech.edu\/people\/john-mcdonald\u0022\u003EJohn F. McDonald\u003C\/a\u003E) have identified differential gene-network changes characteristic of the three most prevalent molecular subtypes of breast cancer, Luminal A, Luminal B, and the highly metastatic Basal-like subtype. In contrast to previous studies, the authors expanded their analysis beyond genes differentially expressed between normal and cancer samples, as differential gene expression may not be a prerequisite for changes in gene-gene interactions.\u0026nbsp;(This story also appeared at \u003Ca href=\u0022https:\/\/medicalxpress.com\/news\/2024-04-gene-networks-aggressive-breast-cancer.html\u0022\u003EMedical Xpress\u003C\/a\u003E and\u0026nbsp;\u003Ca href=\u0022https:\/\/www.miragenews.com\/novel-gene-networks-linked-to-aggressive-breast-1220891\/\u0022\u003EMirage News\u003C\/a\u003E.)\u003C\/p\u003E\r\n","format":"limited_html"}],"field_summary_sentence":"","uid":"36583","created_gmt":"2024-04-25 18:46:27","changed_gmt":"2024-04-30 17:56:16","author":"lvidal7","boilerplate_text":"","field_publication":"","publication":"GEN - Genetic Engineering and Biotechnology News","field_article_url":"","publication_url":"https:\/\/www.genengnews.com\/topics\/gene-network-interactions-shed-insight-into-breast-cancer-onset-and-development\/","dateline":{"date":"2024-04-18T00:00:00-04:00","iso_date":"2024-04-18T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1278","name":"College of Sciences"},{"id":"1275","name":"School of Biological Sciences"}],"categories":[{"id":"138","name":"Biotechnology, Health, Bioengineering, Genetics"},{"id":"140","name":"Cancer Research"},{"id":"135","name":"Research"},{"id":"134","name":"Student and Faculty"}],"keywords":[{"id":"166882","name":"School of Biological Sciences"},{"id":"4896","name":"College of Sciences"},{"id":"191973","name":"Georgia Tech Integrated Cancer Research Center"},{"id":"187423","name":"go-bio"},{"id":"14455","name":"Breast Cancer"},{"id":"193668","name":"gene network interactions"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}