{"674269":{"#nid":"674269","#data":{"type":"event","title":"BioE PhD Proposal Presentation- Ana de Pereda","body":[{"value":"\u003Cp\u003ECommittee\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u2022 Dr. Lily Cheung (Ph.D. Advisor, Chemical Engineering, GT )\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u2022 Dr. Hang Lu (Chemical Engineering, GT)\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u2022 Dr. Mark Styczynski (Chemical Engineering, GT)\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u2022 Dr. John Blazeck (Chemical Engineering, GT)\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u2022 Dr. JC Gumbart (Chemistry and Biochemistry, GT)\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cstrong\u003EExploring the Oligomerization of Sugar Transporters for the Advancement in Plant Systems and Synthetic Biology\u0026nbsp;\u003C\/strong\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003EPlant SWEET proteins play a pivotal role as sugar transporters, contributing to crucial processes in plants such as reproduction, stress resistance, and sugar distribution. This thesis proposal will investigate the oligomerization of these key membrane transporter proteins, aiming to unravel their complex\u0026nbsp;emergent functions. By understanding these functions, the goal is to pioneer the engineering of sugar transporters with novel capabilities. Employing advanced characterization techniques, including native mass-spectrometry and fluorescence-based assays, this study aims to accurately quantify the stoichiometry of SWEET oligomers in both \u003Cem\u003EArabidopsis thaliana\u003C\/em\u003E\u0026nbsp;and yeast heterologous expression systems. Furthermore, the research will establish a comprehensive quantitative model to describe sugar transport dynamics for the oligomeric transporters and their individual subunits. Emphasis will\u0026nbsp;be placed on SWEET proteins associated with plant reproduction to create synthetic sugar pumps designed to enhance sugar allocation to endosperm tissues. Through this interdisciplinary approach, the study seeks to delineate the specific impact oligomerization has on sugar transport across plant membranes, thereby informing the intelligent engineering of plant sugar distribution mechanisms for advancements in agricultural productivity and food security.\u0026nbsp;\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u0026nbsp;\u003C\/p\u003E\r\n","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EBioE PhD Proposal Presentation- \u0022Exploring the Oligomerization of Sugar Transporters for the Advancement in Plant Systems and Synthetic Biology \u0022 - Ana de Pereda\u003C\/p\u003E\r\n","format":"limited_html"}],"field_summary_sentence":[{"value":"\u0022Exploring the Oligomerization of Sugar Transporters for the Advancement in Plant Systems and Synthetic Biology \u0022"}],"uid":"27917","created_gmt":"2024-04-18 22:45:39","changed_gmt":"2024-04-18 22:46:42","author":"Laura Paige","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2024-05-03T15:00:00-04:00","event_time_end":"2024-05-03T17:00:00-04:00","event_time_end_last":"2024-05-03T17:00:00-04:00","gmt_time_start":"2024-05-03 19:00:00","gmt_time_end":"2024-05-03 21:00:00","gmt_time_end_last":"2024-05-03 21:00:00","rrule":null,"timezone":"America\/New_York"},"location":"Ford ES\u0026T Room 1387","extras":[],"groups":[{"id":"65448","name":"Bioengineering Graduate Program"}],"categories":[],"keywords":[{"id":"172056","name":"go-BioE"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}