{"674031":{"#nid":"674031","#data":{"type":"event","title":"Special Seminar - Dr. Mykhailo Kopylov (New York Structural Biology Center \u0026 National Center for In-situ Tomographic Ultramicroscopy )","body":[{"value":"\u003Cp\u003E\u003Cspan\u003E\u003Cspan\u003E\u003Cstrong\u003E\u003Cspan\u003E\u003Cspan\u003EBeyond Icosahedra: The Many Faces of Virus-like Particles Revealed by Cryo Electron Microscopy\u003C\/span\u003E\u003C\/span\u003E\u003C\/strong\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cspan\u003E\u003Cspan\u003E\u003Cstrong\u003E\u003Cspan\u003E\u003Cspan\u003EAbstract:\u003C\/span\u003E\u003C\/span\u003E\u003C\/strong\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cspan\u003E\u003Cspan\u003E\u003Cspan\u003E\u003Cspan\u003ESingle particle analysis (SPA) of cryo electron microscopy (cryEM) data is a powerful tool for structural characterization of biomolecules on a nanoscale level. The perfect sample for cryoEM is a monodisperse homogeneous solution of a single molecule of interest, in a single conformation, however it is not always possible. We use modern SPA tools to characterize a highly heterogenous mixture of virus-like particles (VLPs), explore multiple symmetries formed by VLPs, and highlight \u201cthe good, the bad and the ugly\u201d of data processing.\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/span\u003E\u003C\/p\u003E\r\n\r\n\u003Cp\u003E\u003Cspan\u003E\u003Cspan\u003E\u0026nbsp;\u003C\/span\u003E\u003C\/span\u003EAdditionally, I will share insights into our utilization of bacterial surface display and the advancement of PCR techniques for environmental monitoring, highlighting evolutionary biology\u0027s pivotal role in overcoming complex challenges in clinical laboratory science. Information about other activities at NYSBC will also be described, including subcellular proteomics, correlative light\/electron microscopy, and how to apply to the National EM centers for free access and training.\u003C\/p\u003E\r\n","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EOne in the series of the SoCB seminars.\u003C\/p\u003E\r\n","format":"limited_html"}],"field_summary_sentence":[{"value":"School of Chemistry \u0026 Biochemistry -Seminar Series"}],"uid":"36441","created_gmt":"2024-04-05 19:22:34","changed_gmt":"2024-04-05 19:25:50","author":"slawrence67","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2024-04-10T16:00:00-04:00","event_time_end":"2024-04-10T17:00:00-04:00","event_time_end_last":"2024-04-10T17:00:00-04:00","gmt_time_start":"2024-04-10 20:00:00","gmt_time_end":"2024-04-10 21:00:00","gmt_time_end_last":"2024-04-10 21:00:00","rrule":null,"timezone":"America\/New_York"},"location":"MoSE 4202A","extras":[],"groups":[{"id":"85951","name":"School of Chemistry and Biochemistry"}],"categories":[],"keywords":[],"core_research_areas":[],"news_room_topics":[],"event_categories":[{"id":"1795","name":"Seminar\/Lecture\/Colloquium"}],"invited_audience":[{"id":"78761","name":"Faculty\/Staff"},{"id":"174045","name":"Graduate students"},{"id":"177814","name":"Postdoc"}],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003E\u003Cstrong\u003EHost:\u003C\/strong\u003E M. G. Finn, Ph. D.\u003C\/p\u003E\r\n","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}