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  <title><![CDATA[ISyE Seminar - Sen Na]]></title>
  <body><![CDATA[<h3>Title:</h3>

<p>Practicality meets Optimality: Real-Time Statistical Inference under Complex Constraints</p>

<h3>Abstract:</h3>

<p>Constrained estimation problems are prevalent in statistics, machine learning, and engineering. These problems&nbsp;encompass constrained generalized linear models, constrained deep neural networks, physics-inspired machine&nbsp;learning, algorithmic fairness, and optimal control. However, existing estimation methods under hard constraints&nbsp;rely on either projection or regularization, which may theoretically exhibit optimal efficiency but are impractical&nbsp;or unreasonably fail in reality. This talk aims to bridge the significant gap between practice and theory&nbsp;for constrained estimation problems.</p>

<p>I will begin by introducing the critical methodology used to bridge the gap, called Stochastic Sequential Quadratic&nbsp;Programming. We will see that SQP methods serve as the workhorse for modern scientific machine learning problems&nbsp;and can resolve the failure modes of prevalent regularization-based methods. I will demonstrate how to make&nbsp;SQP adaptive and scalable using various modern techniques, such as stochastic line search, trust region, and dimension&nbsp;reduction.</p>

<p>Additionally, I will show how to further enhance SQP to handle inequality constraints online.<br />
Following the methodology, I will present some selective theories, emphasizing the consistency and efficiency<br />
of the SQP methods. Specifically, I will show that online SQP iterates asymptotically exhibit normal behavior<br />
with a mean of zero and optimal covariance in the Hájek and Le Cam sense. Significantly, the covariance does<br />
not deteriorate even when we apply modern techniques driven by practical concerns. The talk concludes with<br />
experiments on both synthetic and real datasets.</p>

<h3>Bio:</h3>

<p>Sen Na is currently a postdoctoral researcher in the Department of Statistics and the International Computer<br />
Science Institute at UC Berkeley. He received a Ph.D. degree in statistics from the University of Chicago.<br />
Sen Na’s primary research interests lie in the mathematical foundations of data science, encompassing high dimensional&nbsp;statistics, computational statistics, sequential decision-making, and large-scale and stochastic<br />
nonlinear optimization. Additionally, he is passionate about various applications of machine learning methods in&nbsp;scientific fields such as biology, neuroscience, physics, and engineering. Sen Na’s research has been recognized&nbsp;by the prestigious Harper Dissertation Fellowship from UChicago, and he has been selected as one of the&nbsp;Young Researchers in ORIE by Cornell University.</p>
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      <value><![CDATA[<h3>Abstract:</h3>

<p>Constrained estimation problems are prevalent in statistics, machine learning, and engineering. These problems<br />
encompass constrained generalized linear models, constrained deep neural networks, physics-inspired machine<br />
learning, algorithmic fairness, and optimal control. However, existing estimation methods under hard constraints<br />
rely on either projection or regularization, which may theoretically exhibit optimal efficiency but are impractical<br />
or unreasonably fail in reality. This talk aims to bridge the significant gap between practice and theory<br />
for constrained estimation problems.</p>

<p>I will begin by introducing the critical methodology used to bridge the gap, called Stochastic Sequential Quadratic<br />
Programming. We will see that SQP methods serve as the workhorse for modern scientific machine learning problems&nbsp;and can resolve the failure modes of prevalent regularization-based methods. I will demonstrate how to make&nbsp;SQP adaptive and scalable using various modern techniques, such as stochastic line search, trust region, and dimension&nbsp;reduction. Additionally, I will show how to further enhance SQP to handle inequality constraints online.</p>

<p>Following the methodology, I will present some selective theories, emphasizing the consistency and efficiency<br />
of the SQP methods. Specifically, I will show that online SQP iterates asymptotically exhibit normal behavior<br />
with a mean of zero and optimal covariance in the Hájek and Le Cam sense. Significantly, the covariance does<br />
not deteriorate even when we apply modern techniques driven by practical concerns. The talk concludes with<br />
experiments on both synthetic and real datasets.<br />
&nbsp;</p>
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