{"670284":{"#nid":"670284","#data":{"type":"external_news","title":"Researchers Discover New Method To Overcome Antimicrobial Resistance","body":[{"value":"\u003Cp\u003EThe World Health Organization has identified antimicrobial resistance as a worldwide concern because most clinical antibiotics are no longer effective against certain pathogenic bacteria.\u0026nbsp;Antibiotics work by targeting specific parts of a bacteria cell, such as the cell wall or its\u0026nbsp;DNA. Bacteria can become resistant to antibiotics in a number of ways, including by developing efflux pumps \u2014 proteins that are located on the surface of the bacteria cell. When an antibiotic enters the cell, the efflux pump pumps it out of the cell before it can reach its target so that the antibiotic is never able to kill the bacteria. However, in a new study published in \u003Ca href=\u0022https:\/\/www.nature.com\/articles\/s41467-023-39615-x\u0022\u003E\u003Cem\u003ENature Communications\u003C\/em\u003E\u003C\/a\u003E,\u0026nbsp;scientists say they\u0027ve found a new class of molecules that inhibit the efflux pump and make the antibiotic effective again. The researchers include \u003Ca href=\u0022https:\/\/www.linkedin.com\/in\/katie-m-kuo-1a9b4351\u0022\u003EKatie M. Kuo\u003C\/a\u003E, Ph.D. scholar in the \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\u0022\u003ESchool of Chemistry and Biochemistry\u003C\/a\u003E, and \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\/people\/james-c-gumbart\u0022\u003EJames C. Gumbart\u003C\/a\u003E, professor in the \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\u0022\u003ESchool of Chemistry and Biochemistry\u003C\/a\u003E with an adjunct appointment in the \u003Ca href=\u0022https:\/\/physics.gatech.edu\u0022\u003ESchool of Physics\u003C\/a\u003E.\u0026nbsp;\u003C\/p\u003E\r\n","summary":"","format":"limited_html"}],"field_subtitle":"","field_summary":[{"value":"\u003Cp\u003EThe World Health Organization has identified antimicrobial resistance as a worldwide concern because most clinical antibiotics are no longer effective against certain pathogenic bacteria.\u0026nbsp;Antibiotics work by targeting specific parts of a bacteria cell, such as the cell wall or its\u0026nbsp;DNA. Bacteria can become resistant to antibiotics in a number of ways, including by developing efflux pumps \u2014 proteins that are located on the surface of the bacteria cell. When an antibiotic enters the cell, the efflux pump pumps it out of the cell before it can reach its target so that the antibiotic is never able to kill the bacteria. However, in a new study published in \u003Ca href=\u0022https:\/\/www.nature.com\/articles\/s41467-023-39615-x\u0022\u003E\u003Cem\u003ENature Communications\u003C\/em\u003E\u003C\/a\u003E,\u0026nbsp;scientists say they\u0027ve found a new class of molecules that inhibit the efflux pump and make the antibiotic effective again. The researchers include \u003Ca href=\u0022https:\/\/www.linkedin.com\/in\/katie-m-kuo-1a9b4351\u0022\u003EKatie M. Kuo\u003C\/a\u003E, Ph.D. scholar in the \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\u0022\u003ESchool of Chemistry and Biochemistry\u003C\/a\u003E, and \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\/people\/james-c-gumbart\u0022\u003EJames C. Gumbart\u003C\/a\u003E, professor in the \u003Ca href=\u0022https:\/\/chemistry.gatech.edu\u0022\u003ESchool of Chemistry and Biochemistry\u003C\/a\u003E with an adjunct appointment in the \u003Ca href=\u0022https:\/\/physics.gatech.edu\u0022\u003ESchool of Physics\u003C\/a\u003E.\u0026nbsp;\u003C\/p\u003E\r\n","format":"limited_html"}],"field_summary_sentence":"","uid":"34434","created_gmt":"2023-10-09 15:10:11","changed_gmt":"2023-10-09 15:10:11","author":"Renay San Miguel","boilerplate_text":"","field_publication":"","publication":"SciTechDaily","field_article_url":"","publication_url":"https:\/\/scitechdaily.com\/researchers-discover-new-method-to-overcome-antimicrobial-resistance\/","dateline":{"date":"2023-10-06T00:00:00-04:00","iso_date":"2023-10-06T00:00:00-04:00","tz":"America\/New_York"},"extras":[],"groups":[{"id":"1278","name":"College of Sciences"},{"id":"85951","name":"School of Chemistry and Biochemistry"},{"id":"126011","name":"School of Physics"}],"categories":[{"id":"141","name":"Chemistry and Chemical Engineering"},{"id":"146","name":"Life Sciences and Biology"},{"id":"134","name":"Student and Faculty"},{"id":"130","name":"Alumni"},{"id":"135","name":"Research"}],"keywords":[{"id":"4896","name":"College of Sciences"},{"id":"166928","name":"School of Chemistry and Biochemistry"},{"id":"166937","name":"School of Physics"},{"id":"193147","name":"James C. Gumbart"},{"id":"193148","name":"Katie M. Kuo"},{"id":"192971","name":"antimicrobial resistance"},{"id":"193149","name":"efflux pumps"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[],"email":[],"slides":[],"orientation":[],"userdata":""}}}