{"65246":{"#nid":"65246","#data":{"type":"event","title":"CSE DLS Seminar: Linda Petzold","body":[{"value":"\u003Cp\u003E\u003Cstrong\u003EDr. Linda Petzold\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003EUniversity of California Santa Barbara\u003Cstrong\u003E\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003ETitle:\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003ESpatial Stochastic Simulation of Polarization in Yeast Mating\u003Cstrong\u003E\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EAbstract:\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003EIn microscopic systems formed by living cells, the small numbers of some reactant molecules can result in dynamical behavior that is discrete and stochastic rather than continuous and deterministic.\u0026nbsp; Spatio-temporal gradients and patterns play an important role in many of these systems.\u0026nbsp; In this lecture we report on recent progress in the development of computational methods and software for spatial stochastic simulation.\u0026nbsp; Then we describe a spatial stochastic model of polarisome formation in mating yeast.\u0026nbsp; The new model is built on simple mechanistic components, but is able to achieve a highly polarized phenotype with a relatively shallow input gradient, and to track movement in the gradient.\u0026nbsp; The spatial stochastic simulations are able to reproduce experimental observations to an extent that is not possible with deterministic simulation.\u003C\/p\u003E\u003Cp\u003E\u003Cstrong\u003EBio:\u003C\/strong\u003E\u003C\/p\u003E\u003Cp\u003EDr. Linda Petzold is currently Professor in the Department of Computer Science (Chair 2003-2007) and the Department of Mechanical Engineering, and Director of the Computational Science and Engineering Program at the University of California Santa Barbara.\u0026nbsp; She received her Ph.D. in Computer Science in 1978 from the University of Illinois.\u0026nbsp; From 1978-1985 she was a member of the Applied Mathematics Group at Sandia National Laboratories in Livermore, California, from 1985-1991 she was Group Leader of the Numerical Mathematics Group at Lawrence Livermore National Laboratory, and from 1991-1997 she was Professor in the Department of Computer Science at the University of Minnesota.\u0026nbsp; Dr. Petzold is a member of the US National Academy of Engineering.\u0026nbsp; She was recently named the Faculty Research Lecturer for 2011, the highest honor that UCSB bestows to its faculty.\u0026nbsp; She is a Fellow of the ASME,SIAM and AAAS. She was awarded the Wilkinson Prize for Numerical Software in 1991, the Dahlquist Prize in 1999, and the AWM\/SIAM Sonia Kovalevski Prize in 2003.\u0026nbsp; She served as SIAM (Society for Industrial and Applied Mathematics) Vice President at Large from 2000-2001, as SIAM Vice President for Publications from 1993-1998, and as Editor in Chief of the SIAM Journal on Scientific Computing from 1989-1993.\u003C\/p\u003E","summary":null,"format":"limited_html"}],"field_subtitle":"","field_summary":"","field_summary_sentence":[{"value":"Spatial Stochastic Simulation of Polarization in Yeast Mating"}],"uid":"27439","created_gmt":"2011-03-30 13:48:00","changed_gmt":"2016-10-08 01:54:38","author":"Lometa Mitchell","boilerplate_text":"","field_publication":"","field_article_url":"","field_event_time":{"event_time_start":"2011-04-19T12:00:00-04:00","event_time_end":"2011-04-19T13:00:00-04:00","event_time_end_last":"2011-04-19T13:00:00-04:00","gmt_time_start":"2011-04-19 16:00:00","gmt_time_end":"2011-04-19 17:00:00","gmt_time_end_last":"2011-04-19 17:00:00","rrule":null,"timezone":"America\/New_York"},"extras":[],"groups":[{"id":"37041","name":"Computational Science and Engineering"},{"id":"47223","name":"College of Computing"},{"id":"50877","name":"School of Computational Science and Engineering"}],"categories":[],"keywords":[{"id":"7041","name":"computational science \u0026 engineering"},{"id":"12580","name":"CSE DLS"},{"id":"12581","name":"CSE DLS Seminar"}],"core_research_areas":[],"news_room_topics":[],"event_categories":[],"invited_audience":[],"affiliations":[],"classification":[],"areas_of_expertise":[],"news_and_recent_appearances":[],"phone":[],"contact":[{"value":"\u003Cp\u003EEdmond Chow\u003C\/p\u003E\u003Cp\u003E\u003Ca href=\u0022mailto:echow@cc.gatech.edu\u0022\u003Eechow@cc.gatech.edu\u003C\/a\u003E\u003C\/p\u003E","format":"limited_html"}],"email":[],"slides":[],"orientation":[],"userdata":""}}}